- ►cardiovascres.org S Collot-Teixeira, J Martin, C McDermott-Roe … - Cardiovascular research, 2007 - cardiovascres.org CD36 is a multi-ligand scavenger receptor present on the surface of a number of
cells such as platelets, monocytes/macrophages, endothelial and smooth muscle
cells. Monocyte/macrophage CD36 has been shown to play a critical role in ... Cited by 35 - Related articles - All 7 versions
- ►diabetesjournals.org JB Flowers, ME Rabaglia, KL Schueler, MT … - Diabetes, 2007 - Am Diabetes Assoc The lipogenic gene stearoyl-CoA desaturase (SCD)1 appears to be a promising new
target for obesity-related diabetes, as mice deficient in this enzyme are
resistant to diet- and leptin deficiency–induced obesity. The BTBR mouse ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►shouxi.net A Munteanu, M Taddei, I Tamburini, E … - Journal of Biological Chemistry, 2006 - ASBMB Vitamin E deficiency increases expression of the CD36 scavenger receptor,
suggesting specific molecular mechanisms and signaling pathways modulated by
α-tocopherol. We show here that α-tocopherol down-regulated CD36 ... Cited by 18 - Related articles - BL Direct - All 6 versions
M Andersen, B Lenhard, C Whatling, P … - BMC Molecular Biology, 2006 - biomedcentral.com CD36 is a membrane glycoprotein involved in a variety of cellular processes such
as lipid transport, immune regulation, hemostasis, adhesion, angiogenesis and
atherosclerosis. It is expressed in many tissues and cell types, with a ... Cited by 18 - Related articles - Cached - All 7 versions
SC Martinez, K Tanabe, C Cras-Méneur, NA … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Increasing fatty acid concentrations (100–400 μmol/l palmitate or
oleate) led to early Jun NH 2 -terminal kinase (JNK) activation that preceded
induction of ER stress markers and apoptosis. Foxo1 activity was increased ... Cited by 15 - Related articles - BL Direct - All 4 versions
DPY Koonen, RL Jacobs, M Febbraio, ME … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—The etiology of type 2 diabetes often involves diet-induced obesity
(DIO), which is associated with elevated plasma fatty acids and lipoprotein
associated triglycerides. Since aberrant hepatic fatty acid uptake may ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►nih.gov M Kebede, T Alquier, MG Latour, M Semache, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The G-protein–coupled receptor GPR40 is expressed in pancreatic
β-cells and is activated by long-chain fatty acids. Gene deletion studies have
shown that GPR40 mediates, at least in part, fatty acid–amplification of ... Cited by 13 - Related articles - All 4 versions
- ►diabetesjournals.org T Kato, H Shimano, T Yamamoto, M Ishikawa, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Incubation of C57BL/6 islets with palmitate caused inhibition of both
glucose- and potassium-stimulated insulin secretion, but addition of
eicosapentaenoate (EPA) restored both inhibitions. Concomitantly, palmitate ... Cited by 10 - Related articles - All 6 versions
- ►unige.ch [PDF] F Frigerio, G Chaffard, M Berwaer, P Maechler - Biochemical pharmacology, 2006 - Elsevier Topiramate (Topamax), primarily prescribed against epilepsy, was reported to
reduce body weight and to ameliorate glycemic control in obese patients with
diabetes. In rodent models of obesity and diabetes, topiramate treatment ... Cited by 8 - Related articles - All 5 versions
- ►endocrinology-journals.org H Ghanaat-Pour, Z Huang, M Lehtihet, A … - Journal of molecular endocrinology, 2007 - Soc Endocrinology The spontaneously diabetic Goto-Kakizaki (GK) rat is frequently used as a model
for human type 2 diabetes. Selective loss of glucose-sensitive insulin secretion
is an early pathogenetic event in human type 2 diabetes, and such a defect ... Cited by 6 - Related articles - All 3 versions
