- ►ccf.org [PDF] AJ McCullough - Journal of Clinical Gastroenterology, 2006 - journals.lww.com Abstract: Nonalcoholic fatty liver disease (NAFLD) affects ap- proximately 30% of adults and
20% of children in the United States. Nonalcoholic steatohepatitis (NASH) is its most severe
histologic form and progresses to cirrhosis in 20% of these patients. Once developed, ... Cited by 97 - Related articles - BL Direct - All 5 versions
DR Sell, KM Biemel, O Reihl, MO Lederer, CM … - Journal of Biological …, 2005 - ASBMB The extracellular matrix in most tissues is characterized by progressive age-related stiffening
and loss of proteolytic digestibility that are accelerated in diabetes and can be duplicated by
the nonenzymatic reaction of reducing sugars and extracellular matrix proteins. However, ... Cited by 44 - Related articles - All 5 versions
RA Kowluru, V Kowluru, Y Xiong, YS Ho - Free Radical Biology and Medicine, 2006 - Elsevier The retina experiences mitochondrial dysfunction in diabetes, superoxide levels are
elevated, and mitochondrial superoxide dismutase (MnSOD) activity is decreased. Inhibition
of superoxide accumulation in diabetes prevents mitochondrial dysfunction, apoptosis of ... Cited by 40 - Related articles - All 5 versions
- ►diabetesjournals.org AG Huebschmann, JG Regensteiner, H Vlassara, … - Diabetes Care, 2006 - Am Diabetes Assoc The morbidity caused by diabetes has traditionally been classified into macro- and microvascular
complications. Although macrovascular complications have received greater attention, microvascular
complications are unique to diabetes, and hyperglycemia contributes to their ... Cited by 41 - Related articles - All 6 versions
HL Li, Y Huang, CN Zhang, G Liu, YS Wei, AB … - Free Radical Biology and …, 2006 - Elsevier Cardiac hypertrophy is a major cause of morbidity and mortality worldwide. Recent in vitro and
in vivo studies have suggested that reactive oxygen species (ROS) may play an important role
in cardiac hypertrophy. It was therefore thought to be of particular value to examine the ... Cited by 34 - Related articles - All 4 versions
- ►iovs.org M Kanwar, PS Chan, TS Kern, RA Kowluru - Investigative ophthalmology & visual …, 2007 - ARVO RESULTS. Retinal mitochondria had twofold increase in superoxide levels in nontransgenic
(wild-type [WT]) diabetic mice compared with WT nondiabetic mice. In the same retina, diabetes
decreased mitochondrial GSH levels by 40% and complex III activity by approximately ... Cited by 34 - Related articles - BL Direct - All 3 versions
- ►jacn.org S Wolfram - Journal of the American College of Nutrition, 2007 - Am Coll Nutrition Since ancient times green tea has been considered a health-promoting beverage. In recent
years, scientists throughout the world have investigated the potential benefits of green tea and
its most abundant catechin, epigallocatechin gallate (EGCG). The anti-cancer effects of ... Cited by 31 - Related articles - BL Direct - All 5 versions
RA Kowluru, PS Chan - Exp Diabetes Res, 2007 - downloads.hindawi.com Oxygen metabolism is essential for sustaining aerobic life, and normal cellular homeostasis works
on a fine balance between the formation and elimination of reactive oxygen species (ROS). Oxidative
stress, a cytopathic consequence of excessive production of ROS and the suppression of ... Cited by 30 - Related articles - View as HTML - All 13 versions
- ►aspetjournals.org Y Minamiyama, Y Bito, S Takemura, Y Takahashi, S … - Journal of Pharmacology …, 2007 - ASPET Uncoupling protein 2 (UCP2) is an important regulator of intracellular reactive oxygen species
(ROS) production. We determined the effects of calorie restriction (CR) on the dynamic aspects
of mitochondrial ROS production, UCP2, and the nitric oxide (NO)-cGMP pathway in the ... Cited by 24 - Related articles - All 4 versions