L Agius - Biochemical Journal, 2008 - eng.auburn.edu Conversion of glucose into glycogen is a major pathway that contributes to the removal of glucose
from the portal vein by the liver in the postprandial state. It is regulated in part by the increase
in blood-glucose concentration in the portal vein, which activates glucokinase, the first ... Cited by 10 - Related articles - View as HTML - All 5 versions
LJ Hampson, C Arden, L Agius, M Ganotidis, MN … - Bioorganic & medicinal …, 2006 - Elsevier Various ligand binding sites have been identified from crystallography of either rabbit muscle
or human liver phosphorylase that bind physiological or pharmacological ligands, they include
the catalytic site, an allosteric AMP-activator site, a purine nucleoside inhibitor site ... Cited by 9 - Related articles - All 4 versions
JG McCormack - Biochemical Society Transactions, 2006 - biochemsoctrans.org Abstract Scientists and science in the pharmaceutical industry rely heavily on the more academically
orientated basic research carried out at Universities, for first of all training, but also as a source
of new ideas and approaches to drug discovery. Progress in the discovery and ... Cited by 5 - Related articles - View as HTML - BL Direct - All 8 versions
G Dailey - Diabetes Obes Metab, 2008 - interscience.wiley.com The management of type 2 diabetes mellitus (T2DM) typically focuses on correcting dysglycaemia
to reduce risk for microvascular and macrovascular complications, possibly by reducing
glucose-mediated oxidative stress. However, other cardiometabolic risk factors, including ... Cited by 5 - Related articles - All 4 versions
- ►fudan.edu.cn [PDF] MH Jiang, J Fei, MS Lan, ZP Lu, M Liu, WW Fan, X Gao … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Hepatic glucokinase (GCK) is a key enzyme in glucose utilisation. Downregulation
of its activity is associated with insulin resistance and type 2 diabetes mellitus. However, it is
unknown whether hepatic Gck expression is influenced by age and is involved in ageing- ... Cited by 2 - Related articles - All 3 versions
LJ Hampson, P Mackin, L Agius - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Intraportal infusion of serotonin (5- hydroxytryptamine, 5-HT) or inhibitors
of its cellular uptake stimulate hepatic glucose uptake in vivo by either direct or indirect
mechanisms. The aims of this study were to determine the direct effects of 5-HT in ... Related articles - BL Direct - All 4 versions
PS Timiras - Physiological Basis of Aging and Geriatrics, 2007 - books.google.com 13 The Endocrine Pancreas, Obesity, and Diffuse Endocrine and Chemical Mediators Paola
S. Timiras Department of Molecular and Cell Biology, University of California, Berkeley,
Berkeley, California, USA • INTRODUCTION The well-established regulatory action of ... Related articles - All 2 versions
- ►vanderbilt.edu [PDF] CA DiCostanzo - 2005 - etd.library.vanderbilt.edu Page 1. THE REGULATION OF NET HEPATIC GLUCOSE UPTAKE IN VIVO By Catherine
Anne DiCostanzo Dissertation Submitted to the Faculty of the Graduate School of Vanderbilt
University in partial fulfillment of the requirements for the degree of ... Related articles - View as HTML - All 3 versions
张蔓， 刘小雷 - newdrug.cn [Abstract] Glucokinase gene is a candidate gene of maturity onset of diabetes in young II
(MODY2), its mutations and the impairment of activity of mutant GCK proteins cause MODY2.
Therefore, penetrative studies on GCK mutations will be useful in the prevence and ... Related articles - View as HTML
ІІ Частина - vitapol.com.ua О жиріння є однією зі складових метаболічного синдрому, який формується на тлі синдрому
інсу лінорезистентності (ІР) [23]. Коли індекс маси тіла (ІМТ), який визначають за
формулою: маса тіла (кг)/квадрат зросту (м), перевищує 30, це вказує на ожиріння і є ... Related articles - View as HTML - All 3 versions