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Scholar Results 1 - 10 of about 33 citing Gaster: Differential Utilization of Saturated Palmitate and Unsaturated Oleate. (0.08 sec) 

Ceramides in insulin resistance and lipotoxicity


SA Summers - Progress in Lipid Research, 2006 - Elsevier
Obesity predisposes individuals to the development of insulin resistance in skeletal muscle and the
liver, and researchers have recently proposed two mechanisms by which excess adiposity antagonizes
insulin action in peripheral ...
Cited by 114 - Related articles - All 3 versions

Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of …

- physiology.org
JS Lee, SK Pinnamaneni, SJ Eo, IH Cho, … - Journal of applied …, 2006 - Am Physiological Soc
Consumption of a Western diet rich in saturated fats is associated with obesity and insulin
resistance. In some insulin-resistant phenotypes this is associated with accumulation of skeletal
muscle fatty acids. We examined the ...
Cited by 60 - Related articles - BL Direct - All 9 versions

Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid- …


SK Pinnamaneni, RJ Southgate, MA Febbraio, MJ Watt - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis Stearoyl CoA desaturase 1 (SCD1) is implicated in mediating obesity and
insulin resistance. Paradoxically, SCD1 converts saturated fatty acids, the lipid species implicated
in mediating insulin resistance, to ...
Cited by 26 - Related articles - BL Direct - All 4 versions

Saturated, but not unsaturated, fatty acids induce apoptosis of human coronary …

- diabetesjournals.org
K Staiger, H Staiger, C Weigert, C Haas, HU Häring, M … - Diabetes, 2006 - Am Diabetes Assoc
High nonesterified fatty acid (NEFA) concentrations, as observed in the metabolic syndrome, trigger
apoptosis of human umbilical vein endothelial cells. Since endothelial apoptosis may contribute to
atherothrombosis, we studied the ...
Cited by 21 - Related articles - BL Direct - All 6 versions

Muscular diacylglycerol metabolism and insulin resistance


S Timmers, P Schrauwen, J de Vogel - Physiology & Behavior, 2008 - Elsevier
Failure of insulin to elicit an increase in glucose uptake and metabolism in target tissues such as
skeletal muscle is a major characteristic of non-insulin dependent type 2 diabetes mellitus. A
strong correlation between ...
Cited by 21 - Related articles - All 2 versions

Effects of fatty acid regulation on visfatin gene expression in adipocytes


WEN Yu, W Hong-wei, WU Jing, LU Hui-ling, HU Xiu- … - Chinese medical journal, 2006 - cmj.org
Background The levels of long-term elevated serum or intracellular free fatty acid (FFA) induce
insulin resistance associated with central obesity. The insulin-mimetic protein visfatin is
preferentially produced by visceral ...
Cited by 20 - Related articles - Cached - BL Direct - All 7 versions

Eicosapentaenoic acid (20: 5 n-3) increases fatty acid and glucose uptake in …

- jlr.org
V Aas, MH Rokling-Andersen, ET Kase, GH … - The Journal of Lipid …, 2006 - ASBMB
This study was conducted to evaluate the chronic effects of eicosapentaenoic acid (EPA) on fatty
acid and glucose metabolism in human skeletal muscle cells. Uptake of [ 14 C]oleate was increased
>2-fold after preincubation of ...
Cited by 18 - Related articles - BL Direct - All 6 versions

Fatty acid-induced defects in insulin signalling, in myotubes derived from children, …


MA Sabin, CE Stewart, EC Crowne, SJ … - Journal of cellular …, 2007 - interscience.wiley.com
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functional. We recommend using the ...
Cited by 15 - Related articles - BL Direct - All 5 versions

Globular adiponectin resistance develops independently of impaired insulin- …

- physiology.org
KL Mullen, AC Smith, KA Junkin, DJ … - American Journal of …, 2007 - Am Physiological Soc
High-fat (HF) diets induce insulin resistance and alter lipid metabolism, although controversy
exists regarding the impact of saturated vs. polyunsaturated fats. Adiponectin (Ad) stimulates fatty
acid (FA) oxidation and improves ...
Cited by 13 - Related articles - BL Direct - All 6 versions

Triacylglycerol accumulation is not primarily affected in myotubes established from …


M Gaster, H Beck-Nielsen - BBA-Molecular and Cell Biology of Lipids, 2006 - Elsevier
In the present study, we investigated triacylglycerol (TAG) accumulation, glucose and fatty acid
(FA) uptake, and glycogen synthesis (GS) in human myotubes from healthy, lean, and obese subjects
with and without type 2 diabetes ...
Cited by 11 - Related articles - All 4 versions


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