H Noguchi, S Matsumoto - Acta Medica Okayama, 2006 - lib.okayama-u.ac.jp The direct intracellular delivery of proteins has, until recently, been
difficult to achieve, due primar- ily to the bioavailability barrier of the
plasma membrane. During the past 15 years, a variety of peptides called ... Cited by 49 - Related articles - View as HTML - BL Direct - All 8 versions
- ►nih.gov A Chauhan, A Tikoo, AK Kapur, M Singh - Journal of Controlled Release, 2007 - Elsevier Protein transduction with cell penetrating peptides over the past several years
has been shown to be an effective way of delivering proteins in vitro and now
several reports have also shown valuable in vivo applications in correcting ... Cited by 49 - Related articles - All 4 versions
SL Samson, L Chan - Trends in Endocrinology & Metabolism, 2006 - Elsevier A cure for type 1 (insulin dependent) diabetes might be found in generating
surrogate insulin-producing cells to replace β cells. A gene therapy strategy
using constructs designed to allow glucose-regulated insulin transcription ... Cited by 25 - Related articles - All 3 versions
- ►duke.edu [PDF] LT Lock, ES Tzanakakis - Tissue Engineering, 2007 - liebertonline.com Patients with diabetes experience decreased insulin secretion that is linked to
a significant reduction in the number of islet cells. Reversal of diabetes can
be achieved through islet transplantation, but the scarcity of donor islets ... Cited by 14 - Related articles - BL Direct - All 5 versions
H Noguchi, S Matsumoto - Journal of Hepato-Biliary-Pancreatic Surgery, 2006 - Springer 1 Diabetes Research Institute Kyoto, Kyoto, Japan 2 Research Fellow of the Japan
Society for the Promotion of Science (SPD), Kyoto, Japan 3 Department of
Transplantation and Immunology, Kyoto University Graduate School of ... Cited by 13 - Related articles - BL Direct - All 4 versions
M Liu, ZC Han - J Cell Mol Med, 2008 - interscience.wiley.com Mesenchymal stem cells (MSCs) can be derived from adult bone marrow, fat and
several foetal tissues. In vitro, MSCs have the capacity to differentiate into
multiple mesodermal and non-mesodermal cell lineages. Besides, MSCs possess ... Cited by 13 - Related articles - All 3 versions
S Efrat - Advanced drug delivery reviews, 2008 - Elsevier Beta-cell replacement is considered the optimal treatment for type 1 diabetes,
however, it is hindered by a shortage of human organ donors. Given the
difficulty of expanding adult beta cells in vitro, stem/progenitor cells, ... Cited by 12 - Related articles - All 4 versions
- ►psu.edu [PDF] S Matsumoto, H Noguchi, Y Yonekawa, T … - Expert Opin. Biol. Ther., 2006 - informahealthcare.com Pancreatic islet transplantation is one of the options for treating diabetes and
has been shown to improve the quality of life of severe diabetic patients. Since
the Edmonton protocol was announced, islet transplantation have advanced ... Cited by 12 - Related articles - BL Direct - All 8 versions
V Dror, V Nguyen, P Walia, TB Kalynyak, JA … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis The pathogenesis of diabetes and the success of islet
transplantation depend on the control of pancreatic beta cell fate. The Notch
signalling pathway is essential for normal prenatal pancreatic development, ... Cited by 10 - Related articles - BL Direct - All 2 versions
- ►alphamedpress.org CA Fraker, S Alvarez, P Papadopoulos, J … - Stem Cells, 2007 - AlphaMed Press Despite progress in our knowledge about pancreatic islet specification, most
attempts at differentiating stem/progenitor cells into functional,
transplantable β cells have met only with moderate success thus far. A ... Cited by 11 - Related articles - BL Direct - All 6 versions
