- ►physiology.org SW Ryter, J Alam, AMK Choi - Physiological reviews, 2006 - Am Physiological Soc The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1,
HO-2), catalyze the rate-limiting step in the metabolic conversion of heme to
the bile pigments (ie, biliverdin and bilirubin) and thus constitute a ... Cited by 343 - Related articles - BL Direct - All 6 versions
- ►nih.gov M Thirunavukkarasu, SV Penumathsa, S Koneru … - Free Radical Biology and Medicine, 2007 - Elsevier Excessive oxidative stress has been implicated in the pathology and
complications of diabetes, which leads to myocardial ischemia reperfusion
injury. The present study was designed to examine whether resveratrol ... Cited by 48 - Related articles - All 5 versions
S Das, CG Fraga, DK Das - Free radical research, 2006 - informahealthcare.com Recent studies have demonstrated that resveratrol (trans-3,4′,5-trihydroxy
stilbene), a phytoalexin found in the skin and seeds of grapes, can
pharmacologically precondition (PC) the heart through a nitric oxide (NO)- ... Cited by 43 - Related articles - BL Direct - All 5 versions
GG Camici, M Schiavoni, P Francia, M … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Increased production of reactive oxygen species (ROS) and loss of endothelial NO
bioavailability are key features of vascular disease in diabetes mellitus. The
p66 Shc adaptor protein controls cellular responses to oxidative stress. ... Cited by 44 - Related articles - BL Direct - All 10 versions
J Deshane, M Wright, A Agarwal - ACTA BIOCHIMICA POLONICA-ENGLISH EDITION-, 2005 - actabp.pl Heme oxygenase-1 (HO-1) is an enzyme which catalyzes the rate-limiting step in
heme degrada- tion resulting in the formation of iron, carbon monoxide and
biliverdin, which is subsequent- ly converted to bilirubin by biliverdin ... Cited by 30 - Related articles - View as HTML - BL Direct - All 6 versions
L Rodella, BD Lamon, R Rezzani, B Sangras … - Free Radical Biology and Medicine, 2006 - Elsevier Hyperglycemia has been linked to increased oxidative stress, a resultant
endothelial cell dysfunction, and, ultimately, apoptosis. Heme oxygenases
(HO-1/HO-2) and the products of their activity, biliverdin/bilirubin and ... Cited by 30 - Related articles - All 5 versions
- ►aspetjournals.org AL Kruger, SJ Peterson, ML Schwartzman, H … - Journal of Pharmacology and Experimental …, 2006 - ASPET Heme oxygenase (HO) plays a critical role in the regulation of cellular
oxidative stress. The effects of the reactive oxygen species scavenger ebselen
and the HO inducers cobalt protoporphyrin and stannous chloride (SnCl 2 ) ... Cited by 29 - Related articles - BL Direct - All 6 versions
R Öllinger, H Wang, K Yamashita, B Wegiel, … - Antioxidants & Redox Signaling, 2007 - liebertonline.com Bilirubin is the end product of heme catabolism by heme oxygenases. The
inducible form of these enzymes is heme oxygenase-1 (HO-1), which is the
rate-limiting enzyme that can degrade heme into equimolar quanti- ties of ... Cited by 21 - Related articles - All 3 versions
- ►critcaremed.com S Muravchick, RJ Levy - Anesthesiology, 2006 - journals.lww.com Mitochondria produce metabolic energy, serve as biosensors for oxidative stress,
and eventually become effector organelles for cell death through apoptosis. The
extent to which these manifold mitochondrial functions are altered by ... Cited by 17 - Related articles - BL Direct - All 11 versions
