AW Stitt - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2005 - interscience.wiley.com Abstract: Diabetes and age-related eye disorders remain leading causes of blindness
worldwide. While defined pathogenic mechanisms for many of these diseases remain
elusive, there is increasing evidence that products of the Maillard reaction may play an ... Cited by 35 - Related articles - BL Direct - All 6 versions
O Konopatskaya, AJ Churchill, SJ Harper, DO Bates, … - Mol Vis, 2006 - molvis.org Purpose: Hypoxia driven ocular angiogenesis occurs in a range of ischemic retinopathies including
proliferative diabetic retinopathy and retinopathy of prematurity. These conditions are initiated
and sustained by hypoxia dependent vascular endothelial growth factor (VEGF) ... Cited by 35 - Related articles - Cached - All 3 versions
T Shoji, H Koyama, T Morioka, S Tanaka, A Kizu, K … - Diabetes, 2006 - Am Diabetes Assoc Angiogenic response is impaired in diabetes. Here, we examined the involvement of receptor
for advanced glycation end products (RAGE) in diabetes-related impairment of angiogenesis
in vivo. Angiogenesis was determined in reconstituted basement membrane protein ( ... Cited by 27 - Related articles - BL Direct - All 5 versions
H Koyama, H Yamamoto, Y Nishizawa - Molecular Medicine, 2007 - pubmedcentral.nih.gov Receptor for advanced glycation end-products (RAGE) is known to be involved in microvascular
complications in diabetes. RAGE is also profoundly associated with macrovascular complications
in diabetes through regulation of atherogenesis, angiogenic response, vascular injury, ... Cited by 29 - Related articles - BL Direct - All 6 versions
AW Stitt, TM Curtis - Pharmacological Reports, 2005 - rabbit.if-pan.krakow.pl Abstract: Of all microvascular complications of diabetes mellitus, retinopathy remains the most
common. This disease presents major therapeutic problems for the ophthalmologist and despite
many decades of intense research it still constitutes a major cause of blindness in the ... Cited by 16 - Related articles - View as HTML - BL Direct - All 10 versions
RY Yang, GA Rabinovich, FT Liu - Expert Reviews in Molecular …, 2008 - Cambridge Univ Press Galectins are a family of animal lectins that bind b-galactosides. Outside the cell,
galectinsbindtocell-surfaceandextracellularmatrixglycansandtherebyaffecta
varietyofcellularprocesses.However,galectinsarealsodetectableinthecytosol and nucleus, ... Cited by 17 - Related articles - All 2 versions
P Canning, JV Glenn, DK Hsu, FT Liu, TA Gardiner, AW … - Exp Diabetes Res, 2007 - hindawi.com Breakdown of the inner blood-retinal barrier (iBRB) occurs early in diabetes and is central to
the development of sight-threatening diabetic macular edema (DME) as retinopathy
progresses. In the current study, we examined how advanced glycation end prod- ucts ( ... Cited by 11 - Related articles - View as HTML - All 15 versions
- ►nih.gov AM Goodwin - Microvascular research, 2007 - Elsevier Blood vessels, either in insufficient numbers or in excess, contribute to the pathogenesis of many
diseases. Agents that stimulate angiogenesis can improve blood flow in patients with ischemic
diseases, whereas anti-angiogenic agents are used to treat disorders ranging from ... Cited by 13 - Related articles - All 4 versions
- ►fasebj.org JV Glenn, JR Beattie, L Barrett, N Frizzell, SR Thorpe, … - The FASEB Journal, 2007 - FASEB The modification of proteins by nonenzymatic glycation leading to accumulation of advanced
glycation end products (AGEs) is a well-established phenomenon of aging. In the eyes of elderly
patients, these adducts have been observed in retinal pigment epithelium (RPE), ... Cited by 9 - Related articles - BL Direct - All 5 versions
- ►bjmu.edu.cn [PDF] AL Wang, ACH Yu, QH He, XA Zhu, MOM Tso - Experimental eye research, 2007 - Elsevier Diabetic retinopathy induces an inflammatory response in the retina characterized by an increase
in inflammatory cytokines and the activation of microglia. The degree of microglia activation may
influence the extent of retina injury following retinal metabolic stress. We have previously ... Cited by 8 - Related articles - All 4 versions
