- ►physiology.org SW Ryter, J Alam, AMK Choi - Physiological reviews, 2006 - Am Physiological Soc The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1,
HO-2), catalyze the rate-limiting step in the metabolic conversion of heme to
the bile pigments (ie, biliverdin and bilirubin) and thus constitute a ... Cited by 343 - Related articles - BL Direct - All 6 versions
D An, B Rodrigues - American Journal of Physiology- Heart and Circulatory …, 2006 - Am Physiological Soc In patients with diabetes, an increased risk of symptomatic heart failure
usually develops in the presence of hypertension or ischemic heart disease.
However, a predisposition to heart failure might also reflect the effects ... Cited by 66 - Related articles - BL Direct - All 5 versions
S Das, CG Fraga, DK Das - Free radical research, 2006 - informahealthcare.com Recent studies have demonstrated that resveratrol (trans-3,4′,5-trihydroxy
stilbene), a phytoalexin found in the skin and seeds of grapes, can
pharmacologically precondition (PC) the heart through a nitric oxide (NO)- ... Cited by 43 - Related articles - BL Direct - All 5 versions
- ►physiology.org L Bertrand, A Ginion, C Beauloye, AD Hebert … - American Journal of Physiology- Heart and Circulatory …, 2006 - Am Physiological Soc Diabetic hearts are known to be more susceptible to ischemic disease.
Biguanides, like metformin, are known antidiabetic drugs that lower blood
glucose concentrations by decreasing hepatic glucose production and ... Cited by 32 - Related articles - BL Direct - All 3 versions
L Rodella, BD Lamon, R Rezzani, B Sangras … - Free Radical Biology and Medicine, 2006 - Elsevier Hyperglycemia has been linked to increased oxidative stress, a resultant
endothelial cell dysfunction, and, ultimately, apoptosis. Heme oxygenases
(HO-1/HO-2) and the products of their activity, biliverdin/bilirubin and ... Cited by 30 - Related articles - All 5 versions
- ►asnjournals.org P Katavetin, T Miyata, R Inagi, T Tanaka, R … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Vascular endothelial growth factor (VEGF) is an important survival factor for
endothelial cells in hypoxic environments. High glucose regulates certain
aspects of VEGF expression in various cell types, including proximal ... Cited by 28 - Related articles - BL Direct - All 5 versions
C Di Filippo, S Cuzzocrea, F Rossi, R … - Cardiovascular drug reviews, 2006 - interscience.wiley.com The risk factors, such as hypertension and metabolic syndrome, tend to promote
heart pathology. These risk factors can aggravate concomitant heart insults as
well. Diabetes mellitus represents one of the most important risk factors ... Cited by 18 - Related articles - BL Direct - All 4 versions
- ►physiology.org H Su, X Sun, H Ma, HF Zhang, QJ Yu, C … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc There is a close association between hyperglycemia and increased risk of
mortality after acute myocardial infarction (AMI). However, whether acute
hyperglycemia exacerbates myocardial ischemia/reperfusion (MI/R) injury ... Cited by 16 - Related articles - BL Direct - All 5 versions
G Kewalramani, D An, MS Kim, S Ghosh, D Qi, … - Journal of molecular and cellular cardiology, 2007 - Elsevier Flexibility in substrate selection is essential for the heart to maintain
production of energy and contractile function, and is managed through multiple
mechanisms including PPAR-α and AMP-activated protein kinase (AMPK). Rats ... Cited by 14 - Related articles - All 11 versions
