KV Ramana, A Bhatnagar, S Srivastava, UC … - Journal of Biological Chemistry, 2006 - ASBMB Products of lipid peroxidation such as 4-hydroxy-trans-2-nonenal (HNE) trigger
multiple signaling cascades that variably affect cell growth, differentiation,
and apoptosis. Because glutathiolation is a significant metabolic fate of ... Cited by 37 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org [PDF] KV Ramana, MS Willis, MD White, JW Horton, … - Circulation, 2006 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams &
Wilkins, a division of Wolters ... Inflammation in Mice Is Prevented by Aldose Cited by 30 - Related articles - All 11 versions
- ►jbc.org K Kaiserova, S Srivastava, JD Hoetker, SO … - Journal of Biological Chemistry, 2006 - ASBMB Aldose reductase (AR) reduces cytotoxic aldehydes and glutathione conjugates of
aldehydes derived from lipid peroxidation. Its inhibition has been shown to
increase oxidative injury and abolish the late phase of ischemic ... Cited by 22 - Related articles - BL Direct - All 6 versions
- ►jbc.org KV Ramana, AA Fadl, R Tammali, A Reddy, … - Journal of Biological Chemistry, 2006 - ASBMB Abnormal production of inflammatory cytokines and chemokines is a key feature of
bacterial endotoxin, lipopolysaccharide (LPS)-induced inflammation, and
cytotoxicity; however, the mechanisms regulating production of inflammatory ... Cited by 18 - Related articles - All 7 versions
- ►diabetesjournals.org S Srivastava, KV Ramana, R Tammali, SK … - Diabetes, 2006 - Am Diabetes Assoc The objective of this study was to determine whether the polyol pathway enzyme
aldose reductase mediates diabetes abnormalities in vascular smooth muscle cell
(SMC) growth. Aldose reductase inhibitors (tolrestat or sorbinil) or ... Cited by 18 - Related articles - BL Direct - All 7 versions
- ►aacrjournals.org R Tammali, KV Ramana, SS Singhal, S … - Cancer Research, 2006 - AACR Colon cancer, a complex multistep process involving progressive disruption of
homeostatic mechanisms controlling intestinal epithelial
proliferation/inflammation, differentiation, and programmed cell death, is ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►endojournals.org KV Ramana, R Tammali, A Reddy, A … - Endocrinology, 2007 - Endocrine Soc Diabetes is associated with increased generation of cytokines and tissue
inflammation, but it is unclear how increased cytokine synthesis is causally
related to the development of diabetic complications. Here, we report that ... Cited by 13 - Related articles - BL Direct - All 2 versions
- ►nrc-cnrc.gc.ca [PDF] LA Robertson, AJ Kim, GH Werstuck - Canadian journal of physiology and pharmacology, 2006 - article.pubs.nrc-cnrc.gc.ca Abstract: Recent decades have seen a significant increase in the incidence of
diabetes mellitus. The number of individu- als with diabetes is projected to
reach 300 million by the year 2025. Diabetes is a leading cause of ... Cited by 10 - Related articles - BL Direct - All 8 versions
- ►iovs.org U Yadav, SK Srivastava, KV Ramana - Investigative ophthalmology & visual science, 2007 - ARVO METHODS. EIU was induced by a subcutaneous injection of 200 µg
lipopolysaccharide (LPS) in male Lewis rats treated with the AR inhibitor,
zopolrestat (25 mg/kg body weight, intraperitoneally) or its carrier. The ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►nih.gov KV Ramana, SK Srivastava - Cytokine, 2006 - Elsevier Aldose reductase (AR; AKR1B1) a member of aldo-keto reductase super family, that
we had shown earlier mediates cytotoxic signals induced by high glucose,
cytokines and growth factors, also mediates the inflammatory signals ... Cited by 9 - Related articles - All 5 versions