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Scholar Results 1 - 10 of about 25 citing Shibuya: N-acetyl-seryl-aspartyl-lysyl-proline prevents renal insufficiency and mesangial.... (0.06 sec) 

Physiology of local renin-angiotensin systems

- physiology.org
M Paul, P Mehr… - Physiological reviews, 2006 - Am Physiological Soc
Cited by 167 - Related articles - BL Direct - All 4 versions

Renoprotective effect of COMP-angiopoietin-1 in db/db mice with type 2 diabetes

- oxfordjournals.org
S Lee, W Kim, SO Moon, MJ Sung, DH Kim, KP … - Nephrology Dialysis …, 2007 - ERA-EDTA
Results. COMP-Ang1 reduced albuminuria and decreased mesangial expansion, thickening
of the glomerular basement membrane and podocyte foot process broadening and
effacement. COMP-Ang1 suppressed both renal expression of intercellular adhesion ...
Cited by 18 - Related articles - BL Direct - All 9 versions

Decreased endogenous levels of Ac-SDKP promote organ fibrosis

- ahajournals.org
MA Cavasin, TD Liao, XP Yang, JJ Yang, OA Carretero - Hypertension, 2007 - Am Heart Assoc
There is convincing evidence that chronic treatment with N-acetyl-seryl-aspartyl-lysyl-proline
(Ac-SDKP), a peptide normally found in tissues and biological fluids, reduces collagen deposition
in the heart and kidneys of hypertensive rats and rats with myocardial infarction. However, ...
Cited by 11 - Related articles - All 6 versions

N-acetyl-seryl-aspartyl-lysyl-proline ameliorates the progression of renal …

- asnjournals.org
M Omata, H Taniguchi, D Koya, K Kanasaki, R … - Journal of the American …, 2006 - Am Soc Nephrol
N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), which is hydrolyzed by angiotensin-converting
enzyme, is a natural regulator of hematopoiesis. Here it is shown that Ac-SDKP inhibits TGF-
action in mesangial cells. Because TGF- is thought to play a pivotal role in the ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Recent insights into experimental mouse models of diabetic nephropathy


GH Tesch, DJ Nikolic-Paterson - Nephron Exp Nephrol, 2006 - content.karger.com
Background/Aims: Mouse models are an essential experimental tool for investigating the role
of molecular mechanisms and genetic susceptibility in the development of diabetic
nephropathy. Methods: The most widely used inbred strain, the C57BL/6 mouse, is ...
Cited by 8 - Related articles - BL Direct - All 4 versions

Role of N-acetyl-seryl-aspartyl-lysyl-proline in the antifibrotic and anti-inflammatory …

- ahajournals.org
H Peng, OA Carretero, TD Liao, EL Peterson, NE … - Hypertension, 2007 - Am Heart Assoc
Angiotensin-converting enzyme inhibitors (ACEis) are known to have antifibrotic effects on the
heart and kidney in both animal models and humans. N-acetyl-seryl-aspartyl-lysyl-proline is
a natural inhibitor of proliferation of hematopoietic stem cells and a natural substrate of ...
Cited by 9 - Related articles - All 8 versions

High glucose activates PKC-{zeta} and NADPH oxidase through autocrine TGF-{ …

- physiology.org [PDF] 
L Xia, H Wang, S Munk, J Kwan, HJ … - American Journal of …, 2008 - Am Physiological Soc
Page 1. 1 High glucose activates PKC-ζ and NADPH oxidase through autocrine TGF-β1 signaling
in mesangial cells Ling Xia 1,3 , Hong Wang 1,3 , Snezana Munk 1,3 , Janice Kwan 1,3 , Howard
J Goldberg 2,3 , I George Fantus 2,3 and Catharine I Whiteside 1,3 ...
Cited by 9 - Related articles - All 3 versions

N-acetyl-seryl-aspartyl-lysyl-proline inhibits DNA synthesis in human mesangial …


K Kanasaki, M Haneda, T Sugimoto, K Shibuya, M … - … and biophysical research …, 2006 - Elsevier
N-Acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) was originally reported as a natural inhibitor
of the proliferation of stem cells. To elucidate whether Ac-SDKP inhibits the proliferation of human
mesangial cells, we examined the effect of Ac-SDKP on fetal calf serum (FCS)- or platelet- ...
Cited by 8 - Related articles - All 5 versions

Modulation of glomerulosclerosis


LJ Ma, AB Fogo - Seminars in Immunopathology, 2007 - Springer
Abstract Regardless of the initial injury, the long-term consequence for the patient depends upon
the ensuing balance of profibrotic vs reparative modulators activated. The glomerulus has some
capacity for repair. Even when sclerosis has developed with accumulation of extracellular ...
Cited by 5 - Related articles - BL Direct - All 2 versions

TGF-β/Smads 信号通路与糖尿病肾病


肖炜, 马云, 魏连波 - 国外医学: 泌尿系统分册, 2005 - cqvip.com
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维普资讯 中文期刊·专业文章. 维普专业检索Google学术. 临床医学 >> 国外医学:泌尿系统分册 >>
2005年25卷5期 >> 摘要. TGF-β/Smads信号通路与糖尿病肾病. 评论推荐. 下载全文. ...
Cited by 3 - Related articles - All 2 versions


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