- ►diabetesjournals.org GK Bandyopadhyay, JG Yu, J Ofrecio, JM … - Diabetes, 2006 - Am Diabetes Assoc Increased accumulation of fatty acids and their derivatives can impair
insulin-stimulated glucose disposal by skeletal muscle. To characterize the
nature of the defects in lipid metabolism and to evaluate the effects of ... Cited by 78 - Related articles - BL Direct - All 5 versions
- Free from Publisher A Basu, MD Jensen, F McCann, D … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—Pioglitazone increased (P < 0.001 from baseline) total body water
(+2.4 ± 0.5 l) accounting for 75% of the total weight gain (+3.1 ± 2.0 kg) but
did not alter vascular endothelial growth factor concentrations. Total ... Cited by 54 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org VR Vaidyula, AK Rao, M Mozzoli, C Homko, … - Diabetes, 2006 - Am Diabetes Assoc Individuals with chronically elevated glucose and/or insulin levels, ie, most
patients with type 2 diabetes, have accelerated atherosclerosis and are prone to
acute vascular events. We have tested the hypothesis that hyperglycemia ... Cited by 46 - Related articles - BL Direct - All 6 versions
G Boden, M Zhang - Expert Opin. Investig. Drugs, 2006 - Informa Pharma Science Thiazolidinediones (TZDs) are peroxisomal proliferator-activated receptor
(PPAR)-γ agonists. They increase insulin action through several mechanisms
including: stimulation of the expression of genes that increase fat ... Cited by 45 - Related articles - BL Direct - All 5 versions
- ►endojournals.org E Hondares, O Mora, P Yubero, MR de la … - Endocrinology, 2006 - Endocrine Soc Thiazolidinediones (TZDs) are insulin-sensitizing drugs currently used to treat
type 2 diabetes. They are activators of peroxisome proliferator-activated
receptor (PPAR)- , and adipose tissue constitutes a major site for their ... Cited by 42 - Related articles - BL Direct - All 3 versions
M Laplante, WT Festuccia, G Soucy, Y … - Diabetes, 2006 - Am Diabetes Assoc In this study, we aimed to establish the mechanisms whereby peroxisome
proliferator–activated receptor γ (PPARγ) agonism brings about
redistribution of fat toward subcutaneous depots and away from visceral ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►ajcn.org MP Corcoran, S Lamon-Fava, RA Fielding - American Journal of Clinical Nutrition, 2007 - Am Soc Nutrition Mounting evidence indicates that elevated intramyocellular triacylglycerol
concentrations are associated with diminished insulin sensitivity in skeletal
muscle. This lipid accumulation is most likely due to enhanced fatty acid ... Cited by 36 - Related articles - BL Direct - All 12 versions
- ►diabetesjournals.org I Dahlman, M Forsgren, A Sjögren, EA … - Diabetes, 2006 - Am Diabetes Assoc Impaired oxidative phosphorylation is suggested as a factor behind insulin
resistance of skeletal muscle in type 2 diabetes. The role of oxidative
phosphorylation in adipose tissue was elucidated from results of Affymetrix ... Cited by 29 - Related articles - BL Direct - All 5 versions
JP Wilding - Diabetic Medicine, 2007 - interscience.wiley.com The recent increase in the prevalence of obesity has been associated with a
coincident rise in the prevalence of Type 2 diabetes, whereas weight loss has
been shown to decrease the risk of Type 2 diabetes. The pathophysiological ... Cited by 28 - Related articles - BL Direct - All 4 versions
T Cadoudal, JM Blouin, M Collinet, F Fouque, … - Diabetologia, 2007 - Springer Page 1. ARTICLE Acute and selective regulation of glyceroneogenesis and
cytosolic phosphoenolpyruvate carboxykinase in adipose tissue ... Cited by 19 - Related articles - BL Direct - All 4 versions
