- ►nas.edu [PDF] JP Mordes, P Poussier, AR Rossini, EP … - Animal Models of Diabetes: Frontiers in Research - books.google.com 2 Animal Models of Diabetes BBDR Rats and Translational Modeling Fidelity 19
Immunological Perturbation and Diabetes Induction in Other Rat Strains 20
TLRLigation 20 Viral Infection 21 A Working Hypothesis of Autoimmune ... Cited by 43 - Related articles - BL Direct - All 4 versions
N van der Werf, FG Kroese, J Rozing, JL … - Diabetes/Metabolism Reviews - interscience.wiley.com During the last decades, the incidence of type 1 diabetes (T1D) has increased
significantly, reaching percentages of 3% annually worldwide. This increase
suggests that besides genetical factors environmental perturbations ... Cited by 40 - Related articles - BL Direct - All 3 versions
CH June, BR Blazar - Seminars in immunology, 2006 - Elsevier A central goal immunologists has been to develop targeted therapies that will
induce or maintain immunologic tolerance in the absence of potentially harmful
immunosuppression. The ability to isolate and expand regulatory T-cell ... Cited by 35 - Related articles - All 3 versions
- ►shouxi.net D Bruder, AM Westendorf, W Hansen, S … - Diabetes, 2005 - Am Diabetes Assoc Targeting of antigens to immature dendritic cells has been shown to result in
antigen-specific T-cell tolerance in vivo. In the INS-HA/TCR-HA transgenic mouse
model for type 1 diabetes, we tested the potential of the dendritic cell– ... Cited by 33 - Related articles - BL Direct - All 7 versions
- ►jimmunol.org TN Golovina, T Mikheeva, MM Suhoski, NA Aqui … - The Journal of Immunology, 2008 - Am Assoc Immnol The costimulatory requirements required for peripheral blood T regulatory cells
(Tregs) are unclear. Using cell-based artificial APCs we found that CD28 but not
ICOS, OX40, 4-1BB, CD27, or CD40 ligand costimulation maintained high ... Cited by 23 - Related articles - All 5 versions
- ►oxfordjournals.org D Tischner, A Weishaupt, J Brandt, N Muller, … - Brain, 2006 - Oxford Univ Press Recruitment of naturally occurring CD4 + CD25 + regulatory T (T reg ) cells is a
highly promising approach for the treatment of experimental autoimmune
encephalomyelitis (EAE), a widely used model of multiple sclerosis. Here, ... Cited by 15 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org JL Hillebrands, B Whalen, JTJ Visser, J … - The Journal of Immunology, 2006 - Am Assoc Immnol Biobreeding (BB) rats model type 1 autoimmune diabetes (T1D). BB diabetes-prone
(BBDP) rats develop T1D spontaneously. BB diabetes-resistant (BBDR) rats develop
T1D after immunological perturbations that include regulatory T cell (Treg) ... Cited by 13 - Related articles - BL Direct - All 6 versions
S Glisic-Milosavljevic, J Waukau, P Jailwala … - PLoS One, 2007 - pubmedcentral.nih.gov Other: Principal investigator and corresponding author, was instrumental in
study design, analysis guidance, interpretation and writing the manuscript: SG.
Actively participated in study design, experimental execution, analysis of ... Cited by 10 - Related articles - All 4 versions
S Barath, M Aleksza, T Tarr, S Sipka, G … - Lupus, 2007 - lup.sagepub.com Abnormalities of regulatory T cells may play an important role in the loss of
self-tolerance, which is a major characteristic of lupus. The objective of this
study was to determine the ratio and the number of natural CD4 CD25 high ... Cited by 10 - Related articles - BL Direct - All 2 versions
T Orban, J Kis, L Szereday, P Engelmann, K … - Journal of Autoimmunity, 2007 - Elsevier Type 1 diabetes mellitus (T1DM) in humans is characterized by the
T-cell-dependent destruction of the insulin producing pancreatic beta cells;
however, the precise pathogenesis of the disease, especially the initiation ... Cited by 10 - Related articles - All 5 versions
