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Scholar Results 1 - 10 of about 37 citing Kase: Skeletal muscle lipid accumulation in type 2 diabetes may involve the liver X receptor pathway. (0.11 sec) 

Chronic Activation of Liver X Receptor Induces β-Cell Apoptosis Through …

- diabetesjournals.org
SS Choe, AH Choi, JW Lee, KH Kim, JJ Chung, J Park, … - Diabetes, 2007 - Am Diabetes Assoc
Liver X receptor (LXR)α and LXRβ play important roles in fatty acid metabolism and cholesterol
homeostasis. Although the functional roles of LXR in the liver, intestine, fat, and macrophages
are well established, its role in pancreatic β-cells has not been clearly defined. In this ...
Cited by 23 - Related articles - BL Direct - All 6 versions

Activation of liver X receptors promotes lipid accumulation but does not alter insulin …


D Cozzone, C Debard, N Dif, N Ricard, E Disse, J … - Diabetologia, 2006 - Springer
Page 1. Diabetologia (2006) 49: 990–999 DOI 10.1007/s00125-006-0140-8 ARTICLE
D. Cozzone . C. Debard . N. Dif . N. Ricard . E. Disse . J. Vouillarmet . R. Rabasa-Lhoret .
M. Laville . D. Pruneau . J. Rieusset . E. Lefai . H. Vidal ...
Cited by 19 - Related articles - BL Direct - All 2 versions

Oxysterol nuclear receptor LXRβ regulates cholesterol homeostasis and contractile …


K Mouzat, M Prod'Homme, DH Volle, B Sion, P … - Journal of Biological …, 2007 - ASBMB
The uterus is an organ where lipid distribution plays a critical role for its function. Here we show
that nuclear receptor for oxysterols LXRβ prevents accumulation of cholesteryl esters in mouse
myometrium by controlling expression of genes involved in cholesterol efflux and storage ( ...
Cited by 14 - Related articles - All 6 versions

Liver X receptor gene polymorphisms and adipose tissue expression levels in …


I Dahlman, M Nilsson, H Jiao, J Hoffstedt, CM … - Pharmacogenetics …, 2006 - journals.lww.com
Page 1. Original article 881 Liver X receptor gene polymorphisms and adipose tissue expression
levels in obesity Ingrid Dahlman a,* , Maria Nilsson b,* , Hong Jiao b,d , Johan Hoffstedt a , Cecilia
M. Lindgren b,d , Keith Humphreys c , Juha Kere b,d , Jan-A˚ke Gustafsson b , ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Hormonal activity of AIMP1/p43 for glucose homeostasis

- pnas.org
SG Park, YS Kang, JY Kim, CS Lee, YG … - Proceedings of the …, 2006 - National Acad Sciences
AIMP1 (ARS-interacting multifunctional protein 1) was first identified as an auxiliary factor bound
to the multi-ARS (aminoacyl-tRNA synthetase) complex (1–4). AIMP1 interacts with arginyl-tRNA
synthetase to enhance its enzymatic activity (5). AIMP1 is also secreted (6), and its ...
Cited by 11 - Related articles - BL Direct - All 11 versions

Triacylglycerol accumulation is not primarily affected in myotubes established from …


M Gaster, H Beck-Nielsen - BBA-Molecular and Cell Biology of Lipids, 2006 - Elsevier
In the present study, we investigated triacylglycerol (TAG) accumulation, glucose and fatty acid
(FA) uptake, and glycogen synthesis (GS) in human myotubes from healthy, lean, and obese
subjects with and without type 2 diabetes (T2D), exposed to increasing palmitate (PA) ...
Cited by 11 - Related articles - All 4 versions

Liver X receptor antagonist reduces lipid formation and increases glucose …


ET Kase, GH Thoresen, S Westerlund, K Højlund, AC … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Liver X receptors (LXRs) play important roles in lipid and carbohydrate
metabolism. The purpose of the present study was to evaluate effects of the endogenous LXR
agonist 22-R-hydroxycholesterol (22-R-HC) and its stereo- isomer ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Liver X receptor alpha and beta genes have the potential role on loin lean and fat …


M Yu, B Geiger, N Deeb, MF … - Journal of Animal …, 2006 - interscience.wiley.com
Liver X receptor alpha (LXRA) and beta (LXRB) are members of the nuclear receptor subfamily
and are important regulators of genes involved in lipid, fatty acid and glucose metabolism in
liver, and adipose tissue as well as in skeletal muscle. To investigate whether the two ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Physiological differences between human and rat primary hepatocytes in response …

- aspetjournals.org
P Kotokorpi, E Ellis, P Parini, LM Nilsson, S Strom, … - Molecular Pharmacology, 2007 - ASPET
The liver is central to the maintenance of glucose and lipid homeostasis, and liver X receptors
(LXRs) are key regulators of expression of the genes involved. So far, effects of activation of LXR
in human hepatocytes have not been well characterized. Here we show that treatment of ...
Cited by 9 - Related articles - All 4 versions

22-Hydroxycholesterols regulate lipid metabolism differently than T0901317 in …


E Tranheim Kase, B Andersen, HI Nebb, AC Rustan … - BBA-Molecular and Cell …, 2006 - Elsevier
The nuclear liver X receptors (LXRα and β) are regulators of lipid and cholesterol
metabolism. Oxysterols are known LXR ligands, but the functional role of hydroxycholesterols
is at present unknown. In human myotubes, chronic exposure to the LXR ligand ...
Cited by 5 - Related articles - All 4 versions


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