- ►ahajournals.org K Isoda, JL Young, A Zirlik, LA MacFarlane, … - Arteriosclerosis, thrombosis, and vascular biology, 2006 - Am Heart Assoc Methods and Results— Metformin dose-dependently inhibited IL-1ß–induced
release of the pro-inflammatory cytokines IL-6 and IL-8 in ECs, SMCs, and M s.
Investigation of potential signaling pathways demonstrated that metformin ... Cited by 43 - Related articles - All 8 versions
- ►ahajournals.org [PDF] G Ceolotto, A Gallo, I Papparella, L Franco, E … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2007 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams &
Wilkins, a division of Wolters ... Mediated by NAD(P)H Oxidase via Cited by 29 - Related articles - All 7 versions
A Avogaro, GP Fadini, A Gallo, E Pagnin, S … - Nutrition, Metabolism and Cardiovascular Diseases, 2006 - Elsevier We have shown that NADPH oxidase gene expression is increased in circulating
lymphomonocytes from patients with DM, and that this increased gene expression
is dependent upon metabolic control. Hyperglycemia can mediate its adverse ... Cited by 23 - Related articles - All 6 versions
- ►pnas.org P Aguiari, S Leo, B Zavan, V Vindigni, A … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Regeneration of mesenchymal tissues depends on a resident stem cell population,
that in most cases remains elusive in terms of cellular identity and
differentiation signals. We here show that primary cell cultures derived ... Cited by 20 - Related articles - BL Direct - All 10 versions
S Shah, M Iqbal, J Karam, M Salifu, SI … - Antioxidants & redox signaling, 2007 - liebertonline.com D IABETES MELLITUS is a major cardiovascular and renal risk factor and is ranked
as the fifth leading cause of death worldwide (237). The increasing prevalence
of diabetes has led to the increased risk of premature cardiovascular dis- ... Cited by 19 - Related articles - BL Direct - All 4 versions
N Ouslimani, M Mahrouf, J Peynet, D … - Metabolism, 2007 - Elsevier Beyond its antihyperglycemic action, the antidiabetic oral drug metformin
possesses antioxidant properties that may contribute to improve the
cardiovascular deleterious effects of the diabetic disease. We explored ... Cited by 17 - Related articles - All 9 versions
M Mahrouf, N Ouslimani, J Peynet, R Djelidi, … - Biochemical pharmacology, 2006 - Elsevier Oxidative stress plays a major role in the pathogenesis and in the onset of
macrovascular complications of diabetes. We previously reported that the
antihyperglycaemic drug metformin was able to decrease significantly ... Cited by 18 - Related articles - All 4 versions
- Free from Publisher GP Fadini, S Sartore, C Agostini, A Avogaro - Diabetes Care, 2007 - Am Diabetes Assoc Diabetes complications represent a huge burden for patients and health services.
The fight against each single complication has led to significant improvements
in diabetes care, especially for microvascular complications, yet ... Cited by 17 - Related articles - BL Direct - All 6 versions
LE Fridlyand, LH Philipson - Current Diabetes Reviews, 2006 - ingentaconnect.com Abstract: Insulin resistance (IRe) and a failure of insulin secretion are the
major features of the early pathophysiology of type-2 diabetes mellitus (T2D)
but the etiology is still not well understood. We suggest that: 1. The ... Cited by 15 - Related articles - BL Direct - All 2 versions
- ►physiology.org T Matsumoto, E Noguchi, K Ishida, T … - American Journal of Physiology- Heart and Circulatory …, 2008 - Am Physiological Soc We previously reported that in mesenteric arteries from aged Otsuka Long-Evans
Tokushima fatty (OLETF) rats (a type 2 diabetes model) endothelium-derived
hyperpolarizing factor (EDHF)-type relaxation is impaired while endothelium- ... Cited by 11 - Related articles - All 3 versions
