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Scholar Results 1 - 10 of about 18 citing Edgerton: Inhalation of insulin (Exubera) is associated with augmented disposal of portally.... (0.08 sec) 

Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects


JS Skyler, RS Weinstock, P Raskin, JF Yale, E … - Diabetes Care, 2005 - Am Diabetes Assoc
RESULTS—Mean glycosylated hemoglobin (A1C) decreased comparably from baseline in the inhaled and
subcutaneous insulin groups (−0.3 and −0.1%, respectively; adjusted difference −0.16% [CI
−0.34 to 0.01]), with a similar ...
Cited by 104 - Related articles - BL Direct - All 10 versions

Role of the hepatic sympathetic nerves in the regulation of net hepatic glucose …

- physiology.org
CA DiCostanzo, DP Dardevet, DW Neal, … - American Journal of …, 2006 - Am Physiological Soc
Portal glucose delivery enhances net hepatic glucose uptake (NHGU) relative to peripheral glucose
delivery. We hypothesize that the sympathetic nervous system normally restrains NHGU, and portal
glucose delivery relieves the ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Body Weight Changes Associated With Insulin Therapy

- diabetesjournals.org
PA Hollander, A Krasner, S Klioze, P Schwartz, W … - Diabetes Care, 2007 - Am Diabetes Assoc
Weight gain is commonly seen when patients are started on subcutaneous (SC) insulin. In the UK
Prospective Diabetes Study, those assigned insulin gained 4 kg more than those assigned conventional
therapy at 10 years (1). Given that ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Diabetes therapy trials with inhaled insulin


SE Fineberg - Expert Opin. Investig. Drugs, 2006 - Informa Pharma Science
Administration of insulin by inhalation was first attempted > 50 years ago. At that time, little was
known concerning effective delivery systems and insulin formulations. The recent development of
pulmonary delivery systems for the ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Inhalation of human insulin (exubera) augments the efficiency of muscle glucose …

- shouxi.net
DS Edgerton, AD Cherrington, P Williams, DW Neal, M … - Diabetes, 2006 - Am Diabetes Assoc
This study assessed the site of increased glucose uptake resulting from insulin inhalation,
quantified its effect under steady-state glucose concentrations, and identified the time to onset of
effect. Human insulin was ...
Cited by 6 - Related articles - BL Direct - All 6 versions

Mealtime inhaled insulin lowers fasting glucose: a look at possible explanations


JH DeVries - Diabetologia, 2005 - Springer
To the Editor: Recently, two Phase 3 Exubera inhaled insulin trials in type 1 diabetes and a Phase 2
AERx inhaled insulin trial in type 2 diabetes were reported. No overall difference in HbA 1 c was
noted, but fasting plasma glucose ...
Cited by 5 - Related articles - BL Direct - All 3 versions

Insulin treatment and type 1 diabetes topics


ZT Bloomgarden - Diabetes Care, 2006 - Am Diabetes Assoc
Malcolm Nattrass (Birmingham, UK) discussed basal insulin analogs, noting that the ideal approach
will lead to “a flat profile that is reproducible.” The development of basal insulin began with
protamine zinc insulin in 1936, ...
Cited by 5 - Related articles - All 4 versions

Inhaled insulins: the present and future of diabetes therapy


S Del Prato - Current Medical Research and Opinion®, 2006 - informahealthcare.com
0300-7995 doi:10.1185/030079906X132703 All rights reserved: reproduction in whole or part not
permitted ... Current MediCAL reSeArCh And OpiniOn® VOL. 22, Suppl. 3, 2006, S13-S19 © 2006
LibrAphArM LiMited
Cited by 3 - Related articles - All 4 versions

Inhalation of human insulin is associated with improved insulin action compared …

- aspetjournals.org
DS Edgerton, KM Stettler, DW Neal, M Scott, L … - Journal of Pharmacology …, 2006 - ASPET
This study compared the effects of endogenous (portal) insulin secretion versus peripheral insulin
administration with subcutaneous or inhaled human insulin [INH; Exubera, insulin human (rDNA origin)
inhalation powder] on glucose ...
Cited by 3 - Related articles - BL Direct - All 5 versions

Glycemic Exposure Is Affected Favorably by Inhaled Human Insulin (Exubera) as …


M Hompesch, A Kollmeier, K Rave, L … - Diabetes Technology …, 2009 - liebertonline.com
Page 1. Glycemic Exposure Is Affected Favorably by Inhaled Human Insulin (Exubera) as Compared
with Subcutaneous Insulin Glargine (Lantus) in Patients with Type 2 Diabetes Marcus Hompesch,
MD, 1 Alexa Kollmeier, MD, 1 Klaus Rave, MD, 2 Lutz Heinemann, Ph.D., 2 ...
Cited by 1 - Related articles - All 3 versions


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