JS Skyler, RS Weinstock, P Raskin, JF Yale, E … - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS—Mean glycosylated hemoglobin (A1C) decreased comparably from baseline in the inhaled and
subcutaneous insulin groups (−0.3 and −0.1%, respectively; adjusted difference −0.16% [CI
−0.34 to 0.01]), with a similar ... Cited by 104 - Related articles - BL Direct - All 10 versions
- ►physiology.org CA DiCostanzo, DP Dardevet, DW Neal, … - American Journal of …, 2006 - Am Physiological Soc Portal glucose delivery enhances net hepatic glucose uptake (NHGU) relative to peripheral glucose
delivery. We hypothesize that the sympathetic nervous system normally restrains NHGU, and portal
glucose delivery relieves the ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org PA Hollander, A Krasner, S Klioze, P Schwartz, W … - Diabetes Care, 2007 - Am Diabetes Assoc Weight gain is commonly seen when patients are started on subcutaneous (SC) insulin. In the UK
Prospective Diabetes Study, those assigned insulin gained 4 kg more than those assigned conventional
therapy at 10 years (1). Given that ... Cited by 10 - Related articles - BL Direct - All 5 versions
SE Fineberg - Expert Opin. Investig. Drugs, 2006 - Informa Pharma Science Administration of insulin by inhalation was first attempted > 50 years ago. At that time, little was
known concerning effective delivery systems and insulin formulations. The recent development of
pulmonary delivery systems for the ... Cited by 9 - Related articles - BL Direct - All 5 versions
- ►shouxi.net DS Edgerton, AD Cherrington, P Williams, DW Neal, M … - Diabetes, 2006 - Am Diabetes Assoc This study assessed the site of increased glucose uptake resulting from insulin inhalation,
quantified its effect under steady-state glucose concentrations, and identified the time to onset of
effect. Human insulin was ... Cited by 6 - Related articles - BL Direct - All 6 versions
JH DeVries - Diabetologia, 2005 - Springer To the Editor: Recently, two Phase 3 Exubera inhaled insulin trials in type 1 diabetes and a Phase 2
AERx inhaled insulin trial in type 2 diabetes were reported. No overall difference in HbA 1 c was
noted, but fasting plasma glucose ... Cited by 5 - Related articles - BL Direct - All 3 versions
ZT Bloomgarden - Diabetes Care, 2006 - Am Diabetes Assoc Malcolm Nattrass (Birmingham, UK) discussed basal insulin analogs, noting that the ideal approach
will lead to “a flat profile that is reproducible.” The development of basal insulin began with
protamine zinc insulin in 1936, ... Cited by 5 - Related articles - All 4 versions
- ►aspetjournals.org DS Edgerton, KM Stettler, DW Neal, M Scott, L … - Journal of Pharmacology …, 2006 - ASPET This study compared the effects of endogenous (portal) insulin secretion versus peripheral insulin
administration with subcutaneous or inhaled human insulin [INH; Exubera, insulin human (rDNA origin)
inhalation powder] on glucose ... Cited by 3 - Related articles - BL Direct - All 5 versions
M Hompesch, A Kollmeier, K Rave, L … - Diabetes Technology …, 2009 - liebertonline.com Page 1. Glycemic Exposure Is Affected Favorably by Inhaled Human Insulin (Exubera) as Compared
with Subcutaneous Insulin Glargine (Lantus) in Patients with Type 2 Diabetes Marcus Hompesch,
MD, 1 Alexa Kollmeier, MD, 1 Klaus Rave, MD, 2 Lutz Heinemann, Ph.D., 2 ... Cited by 1 - Related articles - All 3 versions