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Scholar Results 1 - 10 of about 74 citing Abate: ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes. (0.08 sec) 

[PDF] The human obesity gene map: the 2005 update


T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel, G … - Obesity, 2006 - pbrc.edu
Abstract RANKINEN, TUOMO, AAMIR ZUBERI, YVON C. CHAGNON, S. JOHN
WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, LOUIS PE´RUSSE, AND CLAUDE
BOUCHARD. The human obesity gene map: the 2005 update. Obesity. 2006;14: ...
Cited by 335 - Related articles - View as HTML - All 6 versions

NPP-type ectophosphodiesterases: unity in diversity

- kuleuven.be [PDF] 
C Stefan, S Jansen, M Bollen - Trends in biochemical sciences, 2005 - Elsevier
Nucleotide pyrophosphatase/phosphodiesterase (NPP)-type ectophosphodiesterases are found
at the cell surface as type-I or type-II transmembrane proteins, but are also found extracellularly
as secreted or shedded enzymes. They hydrolyze pyrophosphate or phosphodiester ...
Cited by 57 - Related articles - All 8 versions

The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin …


S Bacci, O Ludovico, S Prudente, YY Zhang, R Di … - Diabetes, 2005 - Am Diabetes Assoc
Insulin resistance (IR) is pathogenic for type 2 diabetes and coronary artery disease (CAD). The
K121Q polymorphism of the ENPP1/PC-1 gene is associated with IR. Our aim was to investigate
the role of the 121Q variant on the risk of type 2 diabetes and CAD. Nondiabetic control ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Genetics of human obesity


K Clément - Comptes rendus-Biologies, 2006 - Elsevier
• several genetic variants interact with an 'at-risk' environment in common obesities (polygenic
obesities). Here each susceptibility gene, taken individually, would only have a slight effect on
weight. The cumulative contribution of these genes would become significant when there ...
Cited by 47 - Related articles - BL Direct - All 12 versions

Common variants in the ENPP1 gene are not reproducibly associated with …

- diabetesjournals.org
HN Lyon, JC Florez, T Bersaglieri, R Saxena, W … - Diabetes, 2006 - Am Diabetes Assoc
The common missense single nucleotide polymorphism (SNP) K121Q in the ectoenzyme nucleotide
pyrophosphate phosphodiesterase (ENPP1) gene has recently been associated with type 2
diabetes in Italian, US, and South-Asian populations. A three-SNP haplotype, including ...
Cited by 48 - Related articles - BL Direct - All 7 versions

Type-2 diabetes: a cocktail of genetic discovery

- oxfordjournals.org
H Freeman, RD Cox - Human molecular genetics, 2006 - Oxford Univ Press
Diabetes is one of the most challenging health problems of the 21st century with an alarming
increase in the prevalence of type-2 diabetes mellitus (T2DM) and associated conditions such
as hypertension, dyslipidemias and obesity. T2DM is a complex genetic disease ...
Cited by 48 - Related articles - BL Direct - All 8 versions

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 …

- pubget.com [PDF] 
N Grarup, SA Urhammer, J Ek, A Albrechtsen, C … - Diabetologia, 2006 - Springer
Page 1. ARTICLE Studies of the relationship between the ENPP1 K121Q
polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish
white subjects N. Grarup & SA Urhammer & J. Ek & A. Albrechtsen & ...
Cited by 41 - Related articles - BL Direct - All 5 versions

[PDF] Epidemiology of type 2 diabetes: Indian scenario


V Mohan, S Sandeep, R Deepa, B Shah, C … - Indian Journal of …, 2007 - medind.nic.in
India leads the world with largest number of diabetic subjects earning the dubious distinction
of being termed the “diabetes capital of the world”. According to the Diabetes Atlas 2006 published
by the International Diabetes Federation, the number of people with diabetes in India ...
Cited by 40 - Related articles - View as HTML - BL Direct - All 4 versions

New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 …

- diabetesjournals.org
J Bochenski, G Placha, K Wanic, M Malecki, J Sieradzki … - Diabetes, 2006 - Am Diabetes Assoc
The K121Q polymorphism in ectonucleotide pyrophosphatase/phosphodiesterase 1
(ENPP1) is associated with type 2 diabetes and obesity. The possibility of other ENPP1 polymorphisms
influencing these phenotypes has received little attention. Our aim was to examine the ...
Cited by 35 - Related articles - BL Direct - All 6 versions

Role of Genetic Polymorphism Peroxisome Proliferator–Activated Receptor-γ2 …

- diabetesjournals.org
V Radha, KS Vimaleswaran, HNS Babu, N Abate, … - Diabetes care, 2006 - Am Diabetes Assoc
RESULTS—The Caucasian diabetic subjects had significantly lower prevalence of PPAR-γ 12Ala
when compared with the Caucasian nondiabetic subjects (20 vs. 9%, P = 0.006). However, there
were no significant differences between diabetic and nondiabetic subjects with reference ...
Cited by 34 - Related articles - BL Direct - All 5 versions


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