IC Gaemers, AK Groen - Current opinion in lipidology, 2006 - journals.lww.com Recent findings: In the last few years many connections between carbohydrate and triglyceride
homeostasis, as well as inflammation, have surfaced. These seemingly unrelated metabolic
pathways are linked by the action of diverse nuclear receptors. Many intermediates in ... Cited by 24 - Related articles - BL Direct - All 6 versions
J Ciapaite, SJL Bakker, M Diamant, G van Eikenhorst, … - FEBS Journal - interscience.wiley.com Inhibition of the mitochondrial adenine nucleotide translocator (ANT) by long-chain acyl-CoA
esters has been proposed to contribute to cellular dysfunction in obesity and type 2 diabetes
by increasing formation of reactive oxygen species and adenosine via effects on the ... Cited by 11 - Related articles - BL Direct - All 4 versions
JE Carré, M Singer - BBA-Bioenergetics, 2008 - Elsevier Sepsis is a complex pathophysiological disorder arising from a systemic inflammatory response
to infection. Patients are clinically classified according to the presence of signs of inflammation
alone, multiple organ failure (MOF), or organ failure plus hypotension (septic shock). The ... Cited by 8 - Related articles
J Ciapaite, J van Bezu, G van Eikenhorst, SJL … - BBA-Molecular and Cell …, 2007 - Elsevier Free fatty acids may create a state of continuous and progressive damaging to the vascular wall
manifested by endothelial dysfunction. In this study we determine the mechanisms by which
fatty acids palmitate (C16:0) and oleate (C18:1) affect intracellular long chain acyl-CoA ( ... Cited by 6 - Related articles - All 4 versions
J Ciapaite, SJL Bakker, G Van Eikenhorst, MJ … - BBA-Molecular Basis of …, 2007 - Elsevier We proposed that inhibition of mitochondrial adenine nucleotide translocator (ANT) by long chain
acyl-CoA (LCAC) underlies the mechanism associating obesity and type 2 diabetes. Here we
test that after long-term exposure to a high-fat diet (HFD): (i) there is no adaptation of the ... Cited by 8 - Related articles - All 3 versions
- ►nih.gov AC Haagsma, R Abdillahi-Ibrahim, MJ … - Antimicrobial agents …, 2009 - aac.highwire.org The diarylquinoline TMC207 kills Mycobacterium tuberculosis by specifically inhibiting ATP
synthase. We show here that human mitochondrial ATP synthase (50% inhibitory concentration
[IC 50 ] of >200 µM) displayed more than 20,000-fold lower sensitivity for TMC207 ... Cited by 4 - Related articles - All 6 versions
L Acerenza, F Ortega - FEBS journal, 2007 - interscience.wiley.com Deciphering the laws that govern metabolic responses of complex systems is essential to understand
physiological functioning, pathological conditions and the outcome of experimental manipulations
of intact cells. To this aim, a theoretical and experimental sensitivity analysis, called ... Cited by 4 - Related articles - BL Direct - All 4 versions
N Riksen, M Bosselaar, S Bakker, R Heine, G … - Clinical Science, 2007 - submit.clinsci.org Plasma NEFA (non-esterified fatty acid) concentrations are elevated in patients with obesity.
In the present study we first aimed to provide an integral haemodynamic profile of elevated plasma
NEFAs by the simultaneous assessment of blood pressure, pulse wave velocity, FBF ( ... Cited by 2 - Related articles - Cached - BL Direct - All 10 versions
FJ BRUGGEMAN, S ROSSELL, K VAN EUNEN, J … - Springer 1. Systems Biology ................................................................ 240 1.1. Introduction..............................
.................................. 240 1.2. Two Approaches to Systems Biology .................................... 241
1.3. Two Historical Origins of Systems Biology ........... ... ... E. Bertrand and M. Faupel ... Cited by 1 - Related articles - All 4 versions
