T Staeva-Vieira, M Peakman, M Von Herrath - Clinical and Experimental Immunology, 2007 - pubmedcentral.nih.gov Type 1 diabetes (T1D) is often considered the prototype organ-specific
autoimmune disease in clinical immunology circles. The key disease features −
precise destruction of a single endocrine cell type occurring on a distinct ... Cited by 47 - Related articles - BL Direct - All 5 versions
MJ Haller, MA Atkinson, D Schatz - The Pediatric Clinics of North America, 2005 - Elsevier Type 1 diabetes mellitus (T1D) is a heterogeneous disorder characterized by
autoimmune-mediated destruction of pancreatic beta cells that culminates in
absolute insulin deficiency. T1D is most commonly diagnosed in children and ... Cited by 35 - Related articles - All 17 versions
- ►bjmu.edu.cn [PDF] Å Lernmark, CD Agardh - TRENDS in Immunology, 2005 - Elsevier The loss of β cells in type 1 diabetes is the consequence of a T cell-dependent
autoimmune attack. Autoantibodies against GAD65 (Mr 65.000 isoform of glutamic
acid decarboxylase), IA-2 (insulinoma-associated protein IA-2) or insulin, ... Cited by 16 - Related articles - All 6 versions
JS Skyler - Jama, 2007 - Am Med Assoc The immunologic nature of the type 1 DM disease process was firmly established
in humans by studies in the late 1980s and early 1990s demonstrating that immune
intervention in patients with newly diagnosed type 1 DM resulted in a ... Cited by 13 - Related articles - BL Direct - All 4 versions
LC Stene, E Witsø, PA Torjesen, T … - Journal of Autoimmunity, 2007 - Elsevier We describe the design of the MIDIA study and present serial islet autoantibody
data from 3 months of age in the 526 first enrolled children from the general
population carrying the type 1 diabetes high-risk HLA-DRB1*0401-DQA1*03-DQB1 ... Cited by 10 - Related articles - All 4 versions
MA Atkinson, CJ Rhodes - Diabetologia, 2005 - Springer It is easy to see that Meier and colleagues have set out to gain our collective
attention with their report in this issue of Diabetologia [1]. Many notions
concerning the pathogen- esis of type 1 diabetes have been repeated so ... Cited by 8 - Related articles - BL Direct - All 2 versions
X Wang, Z He, S Ghosh - Mathematical biosciences, 2006 - Elsevier The heterogeneity between young- and adult-onset type 1 diabetes (T1D) is well
known, but not well understood. We approach this question through mathematical
formulation and analysis of the dynamic interactions between the immune ... Cited by 2 - Related articles - All 4 versions
J Sherr, E Cengiz, WV Tamborlane - Drug Discovery Today, 2009 - Elsevier Treatment options for pediatric patients living with type 1 diabetes mellitus
(T1DM) have drastically changed over the past 30 years. Technological advances
including the development of continuous subcutaneous insulin infusion ... Cited by 1 - Related articles - All 2 versions
HF Al-Mutairi, AM Mohsen, ZM Al-Mazidi - Kuwait Medical Journal, 2007 - kma.org.kw INTRODUCTION Type 1 diabetes (T1D) is a multi-factorial autoimmune disease
characterized by insulin deficiency, due to the T-cell mediated destruction of
pancreatic β-cells[1,2]. The disease accounts for about 10% of all cases ... Cited by 1 - Related articles - View as HTML - BL Direct - All 2 versions
