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Scholar Results 1 - 10 of about 21 citing McCurdy: Akt2 is essential for the full effect of calorie restriction on insulin-stimulated.... (0.07 sec) 

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging …


JL Barger, T Kayo, JM Vann, EB Arias, J … - PLoS One, 2008 - pubmedcentral.nih.gov
Resveratrol in high doses has been shown to extend lifespan in some studies in
invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed
mice from middle age (14-months) to old age (30-months) either a control ...
Cited by 40 - Related articles - All 6 versions

Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose …


GD Cartee, JFP Wojtaszewski - Applied Physiology, Nutrition, and Metabolism, 2007 - article.pubs.nrc-cnrc.gc.ca
Abstract: Insulin and exercise, the most important physiological stimuli to
increase glucose transport in skeletal muscle, trigger a redistribution of GLUT4
glucose transporter proteins from the cell interior to the cell surface, ...
Cited by 26 - Related articles - Cached - BL Direct - All 4 versions

AS160 phosphorylation is associated with activation of {alpha} 2beta2 {gamma} 1-but not { …

- physiology.org
JT Treebak, JB Birk, AJ Rose, B Kiens, EA … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
We investigated time- and intensity-dependent effects of exercise on
phosphorylation of Akt substrate of 160 kDa (AS160) in human skeletal muscle.
Subjects performed cycle exercise for 90 min (67% O 2 peak , n = 8), 20 min ...
Cited by 26 - Related articles - BL Direct - All 4 versions

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

- physiology.org
K Sakamoto, GD Holman - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
Vesicular traffic of the glucose transporter GLUT4 occurs in response to
insulin, muscle contraction, and metabolic stimuli that lead to changes in the
energy status of the cell. These stimuli are associated with linked kinase ...
Cited by 22 - Related articles - All 6 versions

Role of Akt2 in contraction-stimulated cell signaling and glucose uptake in skeletal muscle

- physiology.org
K Sakamoto, DE Arnolds, N Fujii, HF Kramer, … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
The serine/threonine kinase Akt/PKB plays diverse roles in cells, and genetic
studies have indicated distinct roles for the three Akt isoforms expressed in
mammalian cells and tissues. Akt2 is a key signaling intermediate for ...
Cited by 14 - Related articles - BL Direct - All 3 versions

Serum-and glucocorticoid-inducible kinase 1 mediates salt sensitivity of glucose tolerance

- shouxi.net
KM Boini, AM Hennige, DY Huang, B Friedrich, … - Diabetes, 2006 - Am Diabetes Assoc
Excess salt intake decreases peripheral glucose uptake, thus impairing glucose
tolerance. Stimulation of cellular glucose uptake involves
phosphatidylinositide-3-kinase (PI-3K)–dependent activation of protein ...
Cited by 13 - Related articles - BL Direct - All 6 versions

Evidence for adipose-muscle cross talk: opposing regulation of muscle proteolysis by …

- endojournals.org
Q Zhou, J Du, Z Hu, K Walsh, XH Wang - Endocrinology, 2007 - Endocrine Soc
Illnesses associated with insulin resistance exhibit increases in whole-body
protein degradation and amino acid oxidation. However, the mechanisms
stimulating muscle catabolism under these conditions are not clear. Because ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory …

- physiology.org
CE McCurdy, RT Davidson, GD Cartee - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc
Calorie restriction [CR; 60% of ad libitum (AL) intake] improves
insulin-stimulated glucose transport, concomitant with enhanced phosphorylation
of Akt. The mechanism(s) for the CR-induced increase in Akt phosphorylation ...
Cited by 10 - Related articles - All 6 versions

Hyrtiosal, a PTP1B inhibitor from the marine sponge Hyrtios erectus, shows extensive …


T Sun, Q Wang, Z Yu, Y Zhang, Y Guo, K Chen … - Chembiochem: a European journal of chemical biology, 2007 - ncbi.nlm.nih.gov
Protein tyrosine phosphatase 1B (PTP1B) negatively regulates insulin signaling,
and PTP1B inhibitors have been seen as promising therapeutic agents against
obesity and type 2 diabetes. Here we report that the marine natural product ...
Cited by 8 - Related articles - BL Direct - All 2 versions

Perturbed skeletal muscle insulin signaling in the adult female intrauterine growth-restricted …

- physiology.org
SA Oak, C Tran, G Pan, M Thamotharan, SU … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
To determine the molecular mechanism(s) linking fetal adaptations in
intrauterine growth restriction (IUGR) to adult maladaptations of type 2
diabetes mellitus, we investigated the effect of prenatal seminutrient ...
Cited by 6 - Related articles - BL Direct - All 3 versions


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