- ►ahajournals.org JD Brown, J Plutzky - Circulation, 2007 - Am Heart Assoc Peroxisome proliferator–activated receptors (PPARs) are ligand-activated
transcription factors involved in the transcriptional regulation of key
metabolic pathways such as lipid metabolism, adipogenesis, and insulin ... Cited by 102 - Related articles - All 8 versions
- ►cell.com H Zhang, P Gao, R Fukuda, G Kumar, B … - Cancer Cell, 2007 - Elsevier Many cancer cells are characterized by increased glycolysis and decreased
respiration, even under aerobic conditions. The molecular mechanisms underlying
this metabolic reprogramming are unclear. Here we show that ... Cited by 99 - Related articles - All 18 versions
AE Civitarese, S Carling, LK Heilbronn, MH … - PLoS medicine, 2007 - pubmedcentral.nih.gov The current study was undertaken to examine muscle mitochondrial bioenergetics
in response to caloric restriction alone or in combination with exercise in 36
young (36.8 ± 1.0 y), overweight (body mass index, 27.8 ± 0.7 kg/m 2 ) ... Cited by 97 - Related articles - All 7 versions
FF Samaha, PO Szapary, N Iqbal, MM … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 - Am Heart Assoc Methods and Results— We performed a prospective, double-blinded,
placebo-controlled study of 60 nondiabetic subjects with low high-density
lipoprotein cholesterol (HDL-C) level and metabolic syndrome to ... Cited by 85 - Related articles - All 9 versions
- ►nih.gov AE Civitarese, B Ukropcova, S Carling, M … - Cell metabolism, 2006 - Elsevier Insulin resistance is associated with impaired skeletal muscle oxidation
capacity and reduced mitochondrial number and function. Here, we report that
adiponectin signaling regulates mitochondrial bioenergetics in skeletal ... Cited by 55 - Related articles - All 15 versions
- ►ahajournals.org J Kim, Y Wei, JR Sowers - Circulation research, 2008 - Am Heart Assoc Insulin resistance is characteristic of obesity, type 2 diabetes, and components
of the cardiometabolic syndrome, including hypertension and dyslipidemia, that
collectively contribute to a substantial risk for cardiovascular disease. ... Cited by 49 - Related articles - All 6 versions
- ►endojournals.org I Bogacka, B Ukropcova, M McNeil, JM Gimble … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Results: The treatment of adipocytes with forskolin increased mitochondrial copy
number and the expression of genes involved in mitochondrial biogenesis (PPAR
coactivator 1 and transcriptional factor A) and fatty acid oxidation (PPAR ... Cited by 50 - Related articles - BL Direct - All 5 versions
- ►endojournals.org E Hondares, O Mora, P Yubero, MR de la … - Endocrinology, 2006 - Endocrine Soc Thiazolidinediones (TZDs) are insulin-sensitizing drugs currently used to treat
type 2 diabetes. They are activators of peroxisome proliferator-activated
receptor (PPAR)- , and adipose tissue constitutes a major site for their ... Cited by 42 - Related articles - BL Direct - All 3 versions
M Laplante, WT Festuccia, G Soucy, Y … - Diabetes, 2006 - Am Diabetes Assoc In this study, we aimed to establish the mechanisms whereby peroxisome
proliferator–activated receptor γ (PPARγ) agonism brings about
redistribution of fat toward subcutaneous depots and away from visceral ... Cited by 42 - Related articles - BL Direct - All 4 versions
T Allen, F Zhang, SA Moodie, LE Clemens, A … - Diabetes, 2006 - Am Diabetes Assoc Halofenate has been shown previously to lower triglycerides in dyslipidemic
subjects. In addition, significant decreases in fasting plasma glucose were
observed but only in type 2 diabetic patients. We hypothesized that ... Cited by 37 - Related articles - BL Direct - All 9 versions
