- ►jlr.org BW Wattenberg, SM Pitson, DM Raben - The Journal of Lipid Research, 2006 - ASBMB The sphingosine and diacylglycerol kinases form a superfamily of structurally related lipid
signaling kinases. One of the striking features of these kinases is that although they are clearly
involved in agonist-mediated ... Cited by 39 - Related articles - BL Direct - All 6 versions
- ►jbc.org CM Sutherland, PAB Moretti, NM Hewitt, CJ Bagley, … - Journal of Biological …, 2006 - ASBMB Sphingosine kinases catalyze the formation of sphingosine 1-phosphate, a bioactive lipid involved in
many aspects of cellular regulation, including the fundamental biological processes of cell growth
and survival. A diverse range of ... Cited by 24 - Related articles - BL Direct - All 7 versions
- ►endojournals.org SG Laychock, SM Sessanna, MH Lin, LD Mastrandrea - Endocrinology, 2006 - Endocrine Soc Cytokines mediate pancreatic islet ß-cell apoptosis and necrosis, leading to loss of insulin
secretory capacity and type 1 diabetes mellitus. The cytokines, IL-1ß and interferon- , induced
terminal deoxynucleotidyl ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►auburn.edu [PDF] AE Alewijnse, SLM Peters - European Journal of Pharmacology, 2008 - Elsevier Sphingolipids are biologically active lipids that play important roles in various cellular processes
and the sphingomyelin metabolites ceramide, sphingosine and sphingosine-1-phosphate can act as
signalling molecules in most cell ... Cited by 13 - Related articles - All 4 versions
- ►endojournals.org DJ Jun, JH Lee, BH Choi, TK Koh, DC Ha, MW Jeong, … - Endocrinology, 2006 - Endocrine Soc Sphingosine-1-phosphate (S1P) is a pluripotent lipid mediator that transmits signals through a
family of G protein-coupled receptors to control diverse biological processes. Here, we investigated
the effects of S1P on the levels of ... Cited by 9 - Related articles - BL Direct - All 6 versions
JM Francy, A Nag, EJ Conroy, JA Hengst, JK Yun - BBA-Gene Structure and …, 2007 - Elsevier Sphingosine kinase 1 (SphK1) is a lipid kinase implicated in mitogenic signaling pathways in
vascular smooth muscle cells. We demonstrate that human coronary artery smooth muscle (HCASM) cells
require SphK1 for growth and that ... Cited by 6 - Related articles - All 3 versions
R Kacimi, DA Vessey, N Honbo, JS Karliner - Journal of molecular and cellular …, 2007 - Elsevier Cardiac fibroblasts are critical for the maintenance of extracellular matrix deposition and turnover
in the normal heart and are key mediators of inflammatory and fibrotic myocardial remodeling in the
injured and failing heart. ... Cited by 5 - Related articles - All 8 versions
S Jang, JH Lee, KR Choi, D Kim, HS Yoo, S Oh - Neurochemical Research, 2007 - Springer Abstract LPS-induced inflammation and changes in protein phosphorylation and the JAK-STAT pathway
accompanying glial activation after LPS treatment, were followed by analyzing secreted
proinflammatory cytokine levels. ... Cited by 4 - Related articles - BL Direct - All 4 versions
A Martino, E Volpe, G Auricchio, V Izzi, F … - Scandinavian …, 2007 - interscience.wiley.com Sphingosine 1-phosphate (S1P) is a lipidic messenger known to exert several physiological functions
within the cell. We tested here whether the stimulation of human monocytes with different doses of
S1P might interfere with their ... Cited by 4 - Related articles - BL Direct - All 5 versions
