- ►shouxi.net X Shen, S Zheng, NS Metreveli, PN Epstein - Diabetes, 2006 - Am Diabetes Assoc We previously reported damage and elevated biogenesis in cardiac mitochondria of
a type 1 diabetic mouse model and proposed that mitochondria are one of the
major targets of oxidative stress. In this study, we targeted ... Cited by 54 - Related articles - BL Direct - All 5 versions
H Kaneto, N Katakami, D Kawamori, T … - Antioxidants & redox signaling, 2007 - liebertonline.com F AILURE OF PANCREATIC cells is the common characteris- tic of type 1 and type 2
diabetes. Type 1 diabetes melli- tus is induced by destruction of pancreatic
cells, which is mediated by an autoimmune mechanism and the consequent ... Cited by 47 - Related articles - BL Direct - All 4 versions
K Maiese, SD Morhan, ZZ Chong - Current neurovascular research, 2007 - pubmedcentral.nih.gov Diabetes mellitus (DM) affects approximately 170 million individuals worldwide
and is expected to alter the lives of at least 366 million individuals within a
future span of 25 years. Of even greater concern is the premise that these ... Cited by 46 - Related articles - BL Direct - All 6 versions
RP Robertson, H Zhou, T Zhang, JS Harmon - Cell biochemistry and biophysics, 2007 - Springer Abstract Type 2 diabetes is characterized by a relentless decline in pancreatic
islet beta cell function and worsening hyperglycemia despite optimal medical
treatment. Our central hypothesis is that residual hyperglycemia, espe- ... Cited by 27 - Related articles - BL Direct - All 4 versions
K Maiese, ZZ Chong, YC Shang - Current medicinal chemistry, 2007 - pubmedcentral.nih.gov Diabetes mellitus (DM) is a significant healthcare concern worldwide that
affects more than 165 million individuals leading to cardiovascular disease,
nephropathy, retinopathy, and widespread disease of both the peripheral and ... Cited by 27 - Related articles - BL Direct - All 6 versions
H Kaneto, T Matsuoka, N Katakami, D … - Current Molecular Medicine, 2007 - ingentaconnect.com Department of Internal Medicine and Therapeutics, Osaka University Graduate
School of Medicine, 2-2 Ya- madaoka, Suita, Osaka 565-0871, Japan Abstract:
Failure of pancreatic -cells is the common characteristic of type 1 and ... Cited by 21 - Related articles - BL Direct - All 2 versions
- ►pnas.org Y Emre, C Hurtaud, M Karaca, T Nubel, F … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Infiltration of inflammatory cells into pancreatic islets of Langerhans and
selective destruction of insulin-secreting β-cells are characteristics of type
1 diabetes. Uncoupling protein 2 (UCP2) is a mitochondrial protein ... Cited by 18 - Related articles - BL Direct - All 9 versions
- ►shouxi.net X Li, H Chen, PN Epstein - Diabetes, 2006 - Am Diabetes Assoc It is widely proposed that reactive oxygen species (ROS) contribute to β-cell
death in type 1 diabetes. We tested this in nonobese diabetic (NOD) mice using
β-cell–specific overexpression of three antioxidant proteins: ... Cited by 15 - Related articles - BL Direct - All 6 versions
C McCabe, A Samali, TO'Brien - Biochemical and Biophysical Research …, 2006 - Elsevier Cytokine-induced β cell destruction may be mediated by the generation of nitric
oxide and/or reactive oxygen species. The relative importance of NO and ROS in
cytokine-induced β cell pathophysiology remains unclear. This ... Cited by 12 - Related articles - All 5 versions
XD Wang, MZ Vatamaniuk, SK Wang, CA … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis We previously observed hyperglycaemia,
hyperinsulinaemia, insulin resistance and obesity in Gpx1- overexpressing mice
(OE). Here we determined whether these phenotypes were eliminated by diet ... Cited by 6 - Related articles - All 3 versions
