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Scholar Results 1 - 10 of about 28 citing Suh: Pyruvate administered after severe hypoglycemia reduces neuronal death and cognitive impairment. (0.09 sec) 

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of …

- nih.gov
SW Suh, ET Gum, AM Hamby, PH Chan, RA … - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig
Hypoglycemic coma and brain injury are potential complications of insulin
therapy. Certain neurons in the hippocampus and cerebral cortex are uniquely
vulnerable to hypoglycemic cell death, and oxidative stress is a key event ...
Cited by 49 - Related articles - BL Direct - All 9 versions

NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and …


W Ying - Antioxidants & redox signaling, 2008 - liebertonline.com
III. Introduction III. Metabolism of NAD and NADP A. General information about
NAD and NADP B. NAD synthesis C. NADP synthesis D. Catabolism of NAD and NADP E.
Relationships between NAD and NADP F. NAD transport across mitochondrial ...
Cited by 35 - Related articles - BL Direct - All 2 versions

Hypoglycemia, brain energetics, and hypoglycemic neuronal death


SW Suh, AM Hamby, RA Swanson - Glia, 2007 - interscience.wiley.com
Hypoglycemia is a common and serious problem among diabetic patients receiving
treatment with insulin or other glucose-lowering drugs. Moderate hypoglycemia
impairs neurological function, and severe hypoglycemia leads to death of ...
Cited by 12 - Related articles - BL Direct - All 2 versions

Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway


AL Cai, GJ Zipfel, CT Sheline - Eur J Neurosci, 2006 - interscience.wiley.com
Zinc neurotoxicity has been demonstrated in ischemic, seizure, hypoglycemic, and
trauma-induced neuronal death where Zn 2+ is thought to be synaptically released
and taken up in neighbouring neurons, reaching toxic concentrations. We ...
Cited by 8 - Related articles - BL Direct - All 6 versions

Acute effects of isolated and combined L-alanine and L-glutamine on hepatic …


V Gazola, RF Garcia, R Curi, TC Pithon- … - Cell Biochemistry and Function, 2007 - interscience.wiley.com
The acute effects of isolated and combined L-alanine (L-Ala) and L-glutamine
(L-Gln) on liver gluconeogenesis, ureagenesis and glycaemic recovery during
short-term insulin-induced hypoglycaemia (IIH) were investigated. For this ...
Cited by 7 - Related articles - BL Direct - All 2 versions

Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and …

- nih.gov
S Kahraman, G Fiskum - Neurochemical research, 2007 - Springer
Abstract NAD(P)H autofluorescence was used to verify establishment of metabolic
anoxia using primary cultures of cortical neurons and astrocytes. Cells on cover
slips were placed in a chamber and O ... Keywords Mitochondria Á ...
Cited by 5 - Related articles - BL Direct - All 9 versions

The contribution of the blood glutamate scavenging activity of pyruvate to its neuroprotective …

- weizmann.ac.il [PDF] 
A Zlotnik, B Gurevich, E Cherniavsky, S … - Neurochemical Research, 2008 - Springer
Abstract The removal of excess glutamate from brain fluids after acute insults
such as closed head injury (CHI) and stroke is expected to prevent
excitotoxicity and the ensuing long lasting neurological deficits. Since ...
Cited by 4 - Related articles - BL Direct - All 6 versions

Pyruvate enhances neurological recovery following cardiopulmonary arrest and …

- nih.gov
AB Sharma, MA Barlow, SH Yang, JW … - Resuscitation, 2007 - Elsevier
Neurological deficit score (NDS), evaluated at 2-day recovery, was sharply
increased in NaCl-treated dogs (10.3 ± 3.5) versus shams (1.2 ± 0.4), but
pyruvate treatment mitigated neurological deficit (NDS = 3.3 ± 1.2; P < ...
Cited by 2 - Related articles - All 49 versions

Insulin treatment in intensive care patients


S Derde, I Vanhorebeek, G Van den Berghe - Horm Res, 2009 - content.karger.com
Hyperglycemia is a major risk factor for increased morbidity and mortality in
the intensive care unit. In two large randomized controlled single-center
studies, the maintenance of strict normoglycemia with intensive insulin ...
Cited by 2 - Related articles - All 5 versions

Dual effect of pyruvate in isolated nerve terminals: generation of reactive oxygen species …


L Tretter, B Liktor, V Adam-Vizi - Neurochemical Research, 2005 - Springer
Generation of reactive oxygen species (ROS) in synaptosomes was investigated in
the presence of different substrates. When pyruvate was used as a substrate an
increased rate of hydrogen peroxide formation was detected by the Amplex ...
Cited by 2 - Related articles - BL Direct - All 3 versions


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