JT Treebak, S Glund, A Deshmukh, DK Klein, YC Long, … - Diabetes, 2006 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) is a heterotrimeric protein that regulates glucose transport
mediated by cellular stress or pharmacological agonists such as 5-aminoimidazole-4-carboxamide
1 β-d-ribonucleoside (AICAR). AS160, a Rab GTPase-activating protein, provides a ... Cited by 83 - Related articles - BL Direct - All 7 versions
A Natali, E Ferrannini - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: Insulin resistance, which manifests itself as endogenous glucose overproduction
and reduced insulin-mediated glucose uptake, is a core defect in type 2 diabetes. Metformin
and the peroxisome proliferator-activated receptor-γ agonists, the thiazolidi- nediones ... Cited by 56 - Related articles - BL Direct - All 3 versions
T Fritz, DK Krämer, HKR Karlsson, D Galuska, … - Diabetes/Metabolism … - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 41 - Related articles - BL Direct - All 4 versions
- ►uidaho.edu [PDF] DJ O'Gorman, HKR Karlsson, S McQuaid, O Yousif, Y … - Diabetologia, 2006 - Springer Page 1. ARTICLE Exercise training increases insulin-stimulated glucose disposal and GLUT4
(SLC2A4) protein content in patients with type 2 diabetes DJ O'Gorman & HKR Karlsson &
S. McQuaid & O. Yousif & Y. Rahman & D. Gasparro & S. Glund & ... Cited by 40 - Related articles - BL Direct - All 4 versions
S Ishikura, PJ Bilan, A Klip - Biochemical and biophysical research …, 2007 - Elsevier Insulin causes translocation of glucose transporter GLUT4 to the membrane of muscle and fat
cells, a process requiring Akt activation. The Rab GTPase-activating protein (Rab-GAP) AS160
is inhibited upon phosphorylation by insulin-activated Akt, thereby allowing GLUT4 ... Cited by 37 - Related articles - All 4 versions
EB Taylor, D An, HF Kramer, H Yu, NL Fujii, KSC … - Journal of Biological …, 2008 - ASBMB The Akt substrate of 160 kDa (AS160) is phosphorylated on Akt substrate (PAS) motifs in response
to insulin and contraction in skeletal muscle, regulating glucose uptake. Here we discovered
a dissociation between AS160 protein expression and apparent AS160 PAS ... Cited by 34 - Related articles - All 6 versions
- ►nih.gov TD King, L Song, RS Jope - Biochemical pharmacology, 2006 - Elsevier AMP-activated protein kinase (AMPK) is a key cellular sensor of reduced energy supply that
is activated by increases in the cellular ratio of AMP/ATP. Phenformin and
5-aminoimidazole-4-carboxamide riboside (AICAR) are two drugs widely used to activate ... Cited by 28 - Related articles - All 5 versions
RT Watson, JE Pessin - Cellular Signalling, 2007 - Elsevier Insulin regulates circulating glucose levels by suppressing hepatic glucose production and increasing
glucose transport into muscle and adipose tissues. Defects in these processes are associated
with elevated vascular glucose levels and can lead to increased risk for the development ... Cited by 29 - Related articles - All 4 versions
KM Geraghty, S Chen, JE Harthill, AF … - The Biochemical …, 2007 - pubmedcentral.nih.gov AS160 (Akt substrate of 160 kDa) mediates insulin-stimulated GLUT4 (glucose transporter 4)
translocation, but is widely expressed in insulin-insensitive tissues lacking GLUT4. Having isolated
AS160 by 14-3-3-affinity chromatography, we found that binding of AS160 to 14-3-3 ... Cited by 28 - Related articles - BL Direct - All 6 versions
- ►physiology.org JT Treebak, JB Birk, AJ Rose, B Kiens, EA … - American Journal of …, 2007 - Am Physiological Soc We investigated time- and intensity-dependent effects of exercise on phosphorylation of Akt substrate
of 160 kDa (AS160) in human skeletal muscle. Subjects performed cycle exercise for 90 min
(67% O 2 peak , n = 8), 20 min (80% O 2 peak , n = 11), 2 min (110% of peak work rate, n ... Cited by 26 - Related articles - BL Direct - All 4 versions
