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Scholar Results 1 - 10 of about 25 citing Li: Low-dose poly (ADP-ribose) polymerase inhibitor-containing combination therapies reverse.... (0.12 sec) 

Diabetes and advanced glycoxidation end products

- diabetesjournals.org
… JG Regensteiner, H Vlassara, JEB Reusch - Diabetes Care, 2006 - Am Diabetes Assoc
The morbidity caused by diabetes has traditionally been classified into macro-
and microvascular complications. Although macrovascular complications have
received greater attention, microvascular complications are unique to ...
Cited by 41 - Related articles - All 6 versions

The role of advanced glycation end products in progression and complications of diabetes

- endojournals.org
SY Goh, ME Cooper - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc
Evidence Synthesis: In this review we report on how these AGEs may exert
deleterious effects in diabetes, as well as address current strategies to
interrupt the formation or action of AGEs. First, AGEs act directly to ...
Cited by 42 - Related articles - BL Direct - All 4 versions

Oxidative-Nitrosative Stress and Poly (ADP-Ribose) Polymerase (PARP) Activation in …

- nih.gov
IG Obrosova, VR Drel, P Pacher, O Ilnytska, … - Diabetes, 2005 - Am Diabetes Assoc
Poly(ADP-ribose) polymerase (PARP) activation, an important factor in the
pathogenesis of diabetes complications, is considered a downstream effector of
oxidative-nitrosative stress. However, some recent findings suggest that it ...
Cited by 37 - Related articles - BL Direct - All 11 versions

Poly (ADP-ribose) polymerase inhibitors ameliorate nephropathy of type 2 diabetic Leprdb/ …

- diabetesjournals.org
C Szabó, A Biser, R Benkő, E Böttinger, K … - Diabetes, 2006 - Am Diabetes Assoc
The activation of the poly(ADP-ribose) polymerase (PARP) plays an important role
in the pathophysiology of various diseases associated with oxidative stress. We
found increased amounts of poly(ADP) ribosylated proteins in diabetic ...
Cited by 35 - Related articles - BL Direct - All 6 versions

Poly (ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory …

- nih.gov
O Ilnytska, VV Lyzogubov, MJ Stevens, VR … - Diabetes, 2006 - Am Diabetes Assoc
Poly(ADP-ribose) polymerase (PARP) activation is emerging as a fundamental
mechanism in the pathogenesis of diabetes complications including diabetic
neuropathy. This study evaluated the role of PARP in diabetic sensory ...
Cited by 26 - Related articles - BL Direct - All 10 versions

Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats

- aspetjournals.org
MJ Stevens, F Li, VR Drel, OI Abatan, H Kim, … - Journal of Pharmacology and Experimental …, 2007 - ASPET
In diabetes, activation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP)
is an important effector of oxidative-nitrosative injury, which contributes to
the development of experimental diabetic peripheral neuropathy (DPN). ...
Cited by 21 - Related articles - All 7 versions

Diabetes mellitus and the peripheral nervous system: manifestations and mechanisms


DW Zochodne - Muscle and Nerve, 2007 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 15 - Related articles - BL Direct - All 4 versions

A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin- …


VR Drel, P Pacher, I Vareniuk, I Pavlov, O … - European journal of pharmacology, 2007 - pubmedcentral.nih.gov
Whereas an important role of free radicals and oxidants in peripheral diabetic
neuropathy is well established, the contribution of nitrosative stress and, in
particular, of the highly reactive oxidant peroxynitrite, has not been ...
Cited by 13 - Related articles - All 6 versions

Mechanisms of disease: the oxidative stress theory of diabetic neuropathy


C Figueroa-Romero, M Sadidi, EL Feldman - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer
Abstract Diabetic neuropathy is the most common com- plication of diabetes,
affecting 50% of diabetic patients. Currently, the only treatment for diabetic
neuropathy is glucose control and careful foot care. In this review, we ...
Cited by 11 - Related articles - All 2 versions

Inhibition of NOS-2 induction in LPS-stimulated J774. 2 cells by 1, 5-isoquinolinediol, an …


R Olszanecki, A Gebska, J Jawien, A … - Journal of physiology and pharmacology, 2006 - jpp.krakow.pl
Activation of both poly (ADP-ribose) polymerase (PARP) and inducible nitric
oxide synthase (NOS-2) have been implicated in the pathogenesis of various forms
of inflammation, therefore compounds which may simultaneously inhibit both ...
Cited by 9 - Related articles - Cached - BL Direct - All 7 versions


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