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Scholar Results 1 - 10 of about 31 citing Johnson: Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from.... (0.12 sec) 

Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles


HA Nasrallah - Molecular psychiatry, 2007 - nature.com
Atypical antipsychotic drugs offer several notable benefits over typical
antipsychotics, including greater improvement in negative symptoms, cognitive
function, prevention of deterioration, and quality of life, and fewer ...
Cited by 44 - Related articles - BL Direct - All 5 versions

Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: implications …


KL Houseknecht, AS Robertson, W Zavadoski … - Neuropsychopharmacology, 2006 - nature.com
Although it is generally accepted that atypical antipsychotics differ in their
risk for diabetic side effects, the underlying pharmacological mechanisms are
unknown. Studies on the mechanisms of antipsychotic-induced hyperglycemia ...
Cited by 35 - Related articles - BL Direct - All 6 versions

Asenapine: a novel psychopharmacologic agent with a unique human receptor signature


M Shahid, GB Walker, SH Zorn, EHF Wong - Journal of Psychopharmacology, 2009 - jop.sagepub.com
Schizophrenia is a highly complex, multidimensional disorder with considerable
unmet medical needs in terms of negative, cognitive and affective symptom
alleviation. A number of potential therapeu- tic molecular targets with ...
Cited by 24 - Related articles - All 3 versions

N-Desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, …


NH Jensen, RM Rodriguiz, MG Caron, WC … - Neuropsychopharmacology, 2007 - nature.com
Quetiapine is an atypical antipsychotic drug that is also US FDA approved for
treating bipolar depression, albeit by an unknown mechanism. To discover the
potential mechanism for this apparently unique action, we screened ...
Cited by 25 - Related articles - All 5 versions

Research on adverse drug events. I. Muscarinic M3 receptor binding affinity could predict the …


JS Silvestre, J Prous - Methods and findings in experimental and clinical …, 2005 - journals.prous.com
SUMMARY Antipsychotics are associated with a wide range of adverse effects,
several of which may represent a serious health risk to patients. There is an
increased concern about metabolic disturbances associated with ...
Cited by 22 - Related articles - All 5 versions

Abnormal glucose metabolism in patients treated with antipsychotics


AJ Scheen, MA De Hert - Diabetes and Metabolism, 2007 - Elsevier
Second-generation (atypical) antipsychotic medications are of great benefit to a
wide variety of people with psychiatric disorders, especially patients with
schizophrenia. However, one constellation of adverse effects is an ...
Cited by 21 - Related articles - BL Direct - All 5 versions

Food intake and reward mechanisms in patients with schizophrenia: implications for …


I Elman, D Borsook, SE Lukas - Neuropsychopharmacology, 2006 - nature.com
Obesity is highly prevalent among patients with schizophrenia and is associated
with detrimental health consequences. Although excessive consumption of fast
food and pharmacotherapy with such second-generation antipsychotic agents ...
Cited by 20 - Related articles - BL Direct - All 6 versions

The early effect of olanzapine and risperidone on insulin secretion in atypical-naive …


CC Chiu, KP Chen, HC Liu, ML Lu - Journal of clinical psychopharmacology, 2006 - journals.lww.com
Abstract: Recently, increasing attention has been drawn to the potential
diabetogenic effect of atypical antipsychotics. The goal of this prospective
study is to evaluate the early effect of olanzapine and risperidone ...
Cited by 17 - Related articles - BL Direct - All 5 versions

Critical role of M3 muscarinic receptor in insulin secretion: implications for …


RD Jindal, MS Keshavan - Journal of clinical psychopharmacology, 2006 - journals.lww.com
The work by Gautam et al 1 published in the June issue of Cell Metabolism has
tremendous implications for clinical pharmacology in general and
psychopharmacology in particular. The authors demonstrated glucose ...
Cited by 7 - Related articles - BL Direct - All 3 versions

The atypical antipsychotic clozapine impairs insulin secretion by inhibiting glucose metabolism …


N Sasaki, M Iwase, Y Uchizono, U Nakamura, … - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis Diabetogenic effects of some atypical antipsychotic
drugs have been reported, although the mechanisms are not fully understood. We
investigated the long-term effects of culturing isolated rat pancreatic ...
Cited by 5 - Related articles - BL Direct - All 4 versions


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