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Scholar Results 1 - 10 of about 81 citing Krady: Minocycline reduces proinflammatory cytokine expression, microglial activation, and.... (0.12 sec) 

Retinal angiogenesis in development and disease


RF Gariano, TW Gardner - Nature, 2005 - nature.com
The retina has long been regarded as 'an approachable part of the brain' for investigating neurosensory
processes. Cell biologists are now capitalizing on the accessibility of the retina to investigate
important aspects of developmental angiogenesis, including how it relates to neuronal ...
Cited by 115 - Related articles - BL Direct - All 7 versions

Diabetic retinopathy


DA Antonetti, AJ Barber, SK Bronson, WM Freeman, … - Diabetes, 2006 - Am Diabetes Assoc
Diabetic retinopathy remains a frightening prospect to patients and frustrates physicians. Destruction
of damaged retina by photocoagulation remains the primary treatment nearly 50 years after its
introduction. The diabetes pandemic requires new approaches to understand the ...
Cited by 73 - Related articles - BL Direct - All 9 versions

The Ins2Akita mouse as a model of early retinal complications in diabetes

- iovs.org
AJ Barber, DA Antonetti, TS Kern, CEN Reiter, RS … - … ophthalmology & visual …, 2005 - ARVO
RESULTS. The mean blood glucose of Ins2 Akita mice was significantly elevated, whereas the
body weight at death was reduced compared with that of control animals. Compared with sibling
control mice, the Ins2 Akita mice had increased retinal vascular permeability after 12 ...
Cited by 61 - Related articles - All 4 versions

Diabetes is related to cerebral infarction but not to AD pathology in older persons


Z Arvanitakis, JA Schneider, RS Wilson, Y Li, SE Arnold … - Neurology, 2006 - AAN Enterprises
Methods: Subjects were 233 older Catholic clergy in the Religious Orders Study, who underwent
detailed annual evaluations, including neuropsychological testing, and brain autopsy at time
of death (mean age 86 years, 45% men). Diabetes was identified by annual direct ...
Cited by 44 - Related articles - BL Direct - All 3 versions

[PDF] Contributions of inflammatory processes to the development of the early stages of …


TS Kern - Exp Diabetes Res, 2007 - hindawi.com
Diabetes causes metabolic and physiologic abnormalities in the retina, and these changes suggest
a role for inflammation in the development of diabetic retinopathy. These changes include upregulation
of iNOS, COX-2, ICAM-1, caspase 1, VEGF, and NF-κB, increased production of nitric ...
Cited by 34 - Related articles - View as HTML - All 12 versions

Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease …


BW Festoff, S Ameenuddin, PM Arnold, A … - Journal of …, 2006 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 33 - Related articles - BL Direct - All 5 versions

High glucose increases angiopoietin-2 transcription in microvascular endothelial …

- jbc.org
D Yao, T Taguchi, T Matsumura, R Pestell, D … - Journal of Biological …, 2007 - ASBMB
Methylglyoxal is a highly reactive dicarbonyl degradation product formed from triose phosphates
during glycolysis. Methylglyoxal forms stable adducts primarily with arginine residues of intracellular
proteins. The biologic role of this covalent modification in regulating cell function is not ...
Cited by 28 - Related articles - All 6 versions

Tumor Necrosis Factor-{alpha} Mediates Diabetes-Enhanced Apoptosis of Matrix- …

- amjpathol.org
R Liu, HS Bal, T Desta, Y Behl, DT Graves - American Journal of Pathology, 2006 - ASIP
Diabetics suffer increased infection followed by increased apoptosis of fibroblasts and
bone-lining cells during the healing process. To investigate a potential mechanism, we inoculated
Porphyromonas gingivalis into the scalp of type 2 diabetic (db/db) or control mice and ...
Cited by 19 - Related articles - BL Direct - All 8 versions

Inhibition of caspase-1/interleukin-1β signaling prevents degeneration of retinal …


JA Vincent, S Mohr - Diabetes, 2007 - Am Diabetes Assoc
The proinflammatory cytokine, interleukin (IL)-1β, is known to induce vascular dysfunction and
cell death. We investigated the role of IL-1β and caspase-1 (the enzyme that produces it) in
diabetes-induced degeneration of retinal capillaries. Caspase-1 activity is increased in ...
Cited by 19 - Related articles - BL Direct - All 5 versions

Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat …

- iovs.org
MJ Gastinger, RSJ Singh, AJ Barber - Investigative ophthalmology & visual …, 2006 - ARVO
RESULTS. The number of TUNEL-positive nuclei increased from 29 ± 4 in controls to 72 ± 9
in the STZ-diabetic rat retinas after only 2 weeks of diabetes. In rats, CM-1-immunoreactive
(IR) cells were found primarily in the inner nuclear and ganglion cell layers after 2, 8, and ...
Cited by 18 - Related articles - BL Direct - All 4 versions


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