WF Marshall, S Nonaka - Curr Biol, 2006 - cell.com Cilia are microtubule-based organelles that project like antennae from the
surface of most cells in the body. Motile cilia move fluid past cells, for
example mucus in the airway. Non-motile primary cilia, however, transduce a ... Cited by 75 - Related articles - Cached - All 11 versions
- ►biologists.org BW Bisgrove, HJ Yost - Development, 2006 - dev.biologists.org Cilia are highly conserved organelles that have diverse motility and sensory
functions. Recent discoveries have revealed that cilia also have crucial roles
in cell signaling pathways and in maintaining cellular homeostasis. As ... Cited by 76 - Related articles - BL Direct - All 4 versions
- ►nih.gov JT Eggenschwiler, KV Anderson, 2007 - Annual Reviews Recent studies have revealed unexpected connections between the mammalian
Hedgehog (Hh) signal transduction pathway and the primary cilium, a
microtubule-based organelle that protrudes from the surface of most ... Cited by 69 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org F Hildebrandt, W Zhou - Journal of the American Society of Nephrology, 2007 - Am Soc Nephrol Nephronophthisis (NPHP), an autosomal recessive cystic kidney disease,
represents the most frequent genetic cause of end-stage kidney disease in the
first three decades of life. Contrary to polycystic kidney disease, NPHP ... Cited by 66 - Related articles - All 6 versions
- ►cell.com PN Inglis, KA Boroevich, MR Leroux - Trends in Genetics, 2006 - Elsevier Cilia are slender microtubule-based appendages that emanate from the surfaces of
a large proportion of eukaryotic cells. The motile and non-motile forms of cilia
represent bona fide organelles comprising distinct repertoires of proteins ... Cited by 56 - Related articles - All 8 versions
- ►mcponline.org Q Liu, G Tan, N Levenkova, T Li, EN Pugh Jr, … - Molecular & Cellular Proteomics, 2007 - ASBMB Primary cilia play critical roles in many aspects of biology. Specialized
versions of primary cilia are involved in many aspects of sensation. The single
photoreceptor sensory cilium (PSC) or outer segment elaborated by each rod ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org GB Collin, E Cyr, R Bronson, JD Marshall, EJ … - Human molecular genetics, 2005 - Oxford Univ Press Mutations in the human ALMS1 gene cause Alström syndrome (AS), a progressive
disease characterized by neurosensory deficits and by metabolic defects
including childhood obesity, hyperinsulinemia and Type 2 diabetes. Other ... Cited by 32 - Related articles - All 6 versions
G Li, R Vega, K Nelms, N Gekakis, C … - PLoS Genet, 2007 - genetics.plosjournals.org Premature truncation alleles in the ALMS1 gene are a frequent cause of human
Alström syndrome. Alström syndrome is a rare disorder characterized by early
obesity and sensory impairment, symptoms shared with other genetic diseases ... Cited by 32 - Related articles - Cached - All 11 versions
M Adams, UM Smith, CV Logan, CA Johnson - British Medical Journal, 2008 - jmg.bmj.com Primary cilia have a broad tissue distribution and are present on most cell
types in the human body. Until recently, they were considered to be redundant
organelles, but progress over the past 5 years has led to an understanding ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►molbiolcell.org OE Blacque, C Li, PN Inglis, MA Esmail, G Ou … - Molecular biology of the cell, 2006 - Am Soc Cell Biol The assembly and maintenance of cilia require intraflagellar transport (IFT), a
microtubule-dependent bidirectional motility of multisubunit protein complexes
along ciliary axonemes. Defects in IFT and the functions of motile or ... Cited by 25 - Related articles - BL Direct - All 11 versions
