- ►endojournals.org J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ... Cited by 61 - Related articles - BL Direct - All 4 versions
- ►biologists.org F Chimienti, S Devergnas, F Pattou, F Schuit … - Journal of cell science, 2006 - jcs.biologists.org Insulin-secreting pancreatic beta cells are exceptionally rich in zinc. In these
cells, zinc is required for zinc-insulin crystallization within secretory
vesicles. Secreted zinc has also been proposed to be a paracrine and ... Cited by 50 - Related articles - BL Direct - All 9 versions
- ►endojournals.org HL Olsen, S Theander, K Bokvist, K Buschard … - Endocrinology, 2005 - Endocrine Soc In isolated rat pancreatic -cells, glucose, arginine, and the sulfonylurea
tolbutamide stimulated glucagon release. The effect of glucose was abolished by
the K ATP -channel opener diazoxide as well as by mannoheptulose and azide, ... Cited by 43 - Related articles - BL Direct - All 5 versions
JJ Meier, A Gethmann, O Götze, B Gallwitz, … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: Diabetic dyslipidaemia con- tributes to the excess
morbidity and mortality in patients with type 2 diabetes. Exogenous
glucagon-like peptide 1 (GLP-1) lowers postprandial glycaemia predominantly ... Cited by 36 - Related articles - BL Direct - All 3 versions
- ►endojournals.org BE Dunning, JE Gerich - Endocrine reviews, 2007 - Endocrine Soc The hyperglycemic activity of pancreatic extracts was encountered some 80 yr ago
during efforts to optimize methods for the purification of insulin. The
hyperglycemic substance was named "glucagon," and it was subsequently ... Cited by 32 - Related articles - BL Direct - All 5 versions
- ►pubget.com [PDF] J Bryan, A Muñoz, X Zhang, M Düfer, G Drews … - Pflügers Archiv European Journal of Physiology, 2007 - Springer Abstract The sulfonylurea receptors (SURs) ABCC8/ SUR1 and ABCC9/SUR2 are
members of the C-branch of the transport adenosine triphosphatase superfamily.
Unlike their brethren, the SURs have no identified transport function; ... Cited by 32 - Related articles - BL Direct - All 6 versions
PE MacDonald, YZ De Marinis, R Ramracheya, … - PLoS Biol, 2007 - biology.plosjournals.org Glucagon, secreted from pancreatic islet α cells, stimulates gluconeogenesis
and liver glycogen breakdown. The mechanism regulating glucagon release is
debated, and variously attributed to neuronal control, paracrine control by ... Cited by 26 - Related articles - Cached - All 7 versions
- ►jbc.org AV Gyulkhandanyan, SC Lee, G Bikopoulos, … - Journal of Biological Chemistry, 2006 - ASBMB In pancreatic -cells Zn 2+ is crucial for insulin biosynthesis and exocytosis.
Despite this, little is known about mechanisms of Zn 2+ transport into -cells or
the regulation and compartmentalization of Zn 2+ within this cell type. ... Cited by 25 - Related articles - BL Direct - All 4 versions
C Devirgiliis, PD Zalewski, G Perozzi, C … - … Research-Fundamental and Molecular Mechanisms of …, 2007 - Elsevier The group IIb metal zinc (Zn) is an essential dietary component that can be
found in protein rich foods such as meat, seafood and legumes. Thousands of
genes encoding Zn binding proteins were identified, especially after the ... Cited by 24 - Related articles - All 3 versions
A Salehi, E Vieira, E Gylfe - Diabetes, 2006 - Am Diabetes Assoc Hypersecretion of glucagon contributes to the dysregulation of glucose
homeostasis in diabetes. To clarify the underlying mechanism, glucose-regulated
glucagon secretion was studied in mouse pancreatic islets and clonal ... Cited by 24 - Related articles - BL Direct - All 5 versions
