SA Summers - Progress in Lipid Research, 2006 - Elsevier Obesity predisposes individuals to the development of insulin resistance in
skeletal muscle and the liver, and researchers have recently proposed two
mechanisms by which excess adiposity antagonizes insulin action in ... Cited by 114 - Related articles - All 3 versions
- ►physoc.org P Newsholme, EP Haber, SM Hirabara, ELO … - The Journal of Physiology, 2007 - Physiological Soc It is now widely accepted, given the current weight of experimental evidence,
that reactive oxygen species (ROS) contribute to cell and tissue dysfunction and
damage caused by glucolipotoxicity in diabetes. The source of ROS in the ... Cited by 60 - Related articles - BL Direct - All 8 versions
- ►nih.gov VR Drel, P Pacher, MJ Stevens, IG Obrosova - Free Radical Biology and Medicine, 2006 - Elsevier Both increased aldose reductase (AR) activity and oxidative/nitrosative stress
have been implicated in the pathogenesis of diabetic nephropathy, but the
relation between the two factors remains a subject of debate. This study ... Cited by 34 - Related articles - All 6 versions
- ►molbiolcell.org NM Borradaile, KK Buhman, LL Listenberger, … - Molecular biology of the cell, 2006 - Am Soc Cell Biol The deleterious consequences of fatty acid (FA) and neutral lipid accumulation
in nonadipose tissues, such as the heart, contribute to the pathogenesis of type
2 diabetes. To elucidate mechanisms of FA-induced cell death, or ... Cited by 30 - Related articles - BL Direct - All 6 versions
- ►endojournals.org WL Holland, SA Summers - Endocrine Reviews, 2008 - Endocrine Soc Obesity and dyslipidemia are risk factors for metabolic disorders including
diabetes and cardiovascular disease. Sphingolipids such as ceramide and
glucosylceramides, while being a relatively minor component of the lipid ... Cited by 29 - Related articles - All 7 versions
TA Miller, NK LeBrasseur, GM Cote, MP … - Biochemical and Biophysical Research …, 2005 - Elsevier The cytotoxicity of saturated fatty acids has been implicated in the
pathophysiology of cardiovascular disease, though their effects on cardiac
myocytes are incompletely understood. We examined the effects of palmitate ... Cited by 25 - Related articles - All 4 versions
- ►ahajournals.org [PDF] N Clavreul, MM Bachschmid, X Hou, C Shi, A … - Arteriosclerosis, thrombosis, and vascular biology, 2006 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams &
Wilkins, a division of Wolters ... S-Glutathiolation of p21ras by ... Cited by 25 - Related articles - All 9 versions
- ►physiology.org W Guo, S Wong, W Xie, T Lei, Z Luo - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Although fatty acids enhance preadipocyte differentiation in the presence of
adequate hormone cocktails, little is known regarding their effects in the
absence of these hormones. We have now shown that palmitate, a common ... Cited by 24 - Related articles - BL Direct - All 4 versions
L Li, G Renier - Metabolism, 2006 - Elsevier Increasing evidence indicates that advanced glycation end products (AGEs)
promote retinal alterations through oxidative stress. However, the pathways
involved in AGE-induced generation of reactive oxygen species (ROS) in ... Cited by 23 - Related articles - All 6 versions
