K Srinivasan, P Ramarao - Indian Journal of Medical Research, 2007 - icmr.nic.in Type 2 diabetes is a complex and heterogeneous disorder presently affecting more
than 100 million people worldwide and causing serious socio-economic problems.
Appropriate experimental models are essential tools for understanding the ... Cited by 25 - Related articles - View as HTML - BL Direct - All 3 versions
- ►genetics.org X Cui, J Affourtit, KR Shockley, Y Woo, GA … - Genetics, 2006 - Genetics Soc America Genetic analysis of transcriptional regulation is a rapidly emerging field of
investigation that promises to shed light on the regulatory networks that
control gene expression. Although a number of such studies have been ... Cited by 15 - Related articles - BL Direct - All 8 versions
- ►endojournals.org EH Leiter, PC Reifsnyder, W Zhang, H Pan, Q … - Endocrinology, 2006 - Endocrine Soc Polygenic mouse models for obesity-induced type 2 diabetes (T2D) more accurately
reflect the most common manifestations of the human disease. Two inbred mouse
strains (NON/Lt and NZO/HlLt) separately contributed T2D susceptibility- ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►jbc.org RB Sher, C Aoyama, KA Huebsch, S Ji, J … - Journal of Biological Chemistry, 2006 - ASBMB Muscular dystrophies include a diverse group of genetically heterogeneous
disorders that together affect 1 in 2000 births worldwide. The diseases are
characterized by progressive muscle weakness and wasting that lead to ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►nutrition.org CS Hartz, KM Nieman, RL Jacobs, DE Vance, … - Journal of Nutrition, 2006 - Am Soc Nutrition Phosphatidylcholine is an essential phospholipid that is synthesized by 2
different pathways, the CDP-choline pathway and the methylation of
phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase ... Cited by 8 - Related articles - BL Direct - All 5 versions
- ►theclinics.com JH Henriksen, H Ring-Larsen - Journal of Hepatology, 2008 - Elsevier We conducted an unplanned interim analysis of a randomized, multicenter,
open-label, noninferiority trial involving 4447 patients with type 2 diabetes
who had inadequate glycemic control while receiving metformin or ... Cited by 8 - Related articles - All 15 versions
- ►jbc.org DE Vance, Z Li, RL Jacobs - Journal of Biological Chemistry, 2007 - ASBMB In 1961, when Bremer and Greenberg (1) characterized the methylation reactions
that convert phosphatidylethanolamine (PE) 4 to phosphatidylcholine (PC), it is
unlikely that they would have predicted the physiological impact of this ... Cited by 7 - Related articles - All 4 versions
O Šeda, L Šedová, O Oliyarnyk, L Kazdová, … - Pharmacogenomics, 2008 - Future Medicine * These authors contributed equally to this work. ... Introduction:
Thiazolidinediones are increasingly used drugs for the treatment of Type 2
diabetes. The individual response to thiazolidinedione therapy, ranging ... Cited by 3 - Related articles - BL Direct - All 4 versions
- ►nih.gov HJ Pan, DS Agate, BL King, MK Wu, SL … - FEBS letters, 2006 - Elsevier New Zealand obese (NZO/HlLt) male mice develop polygenic diabetes and altered
phosphatidylcholine metabolism. The gene encoding phosphatidylcholine transfer
protein (PC-TP) is sited within the support interval for Nidd3, a recessive ... Cited by 3 - Related articles - All 12 versions
BC Fam, S Andrikopoulos - Animal models of diabetes: frontiers in research, 2007 - books.google.com 6 The New Zealand Obese Mouse: Polygenic Model of Obesity, Glucose Intolerance,
and the Metabolic Syndrome Barbara C. Fam and Sofianos Andrikopoulos CONTENTS
Background 140 Obesity and Metabolic Characteristics of the NZO Mouse 141 ... Cited by 3 - Related articles
