- ►rayandterry.com [PDF] M Lagouge, C Argmann, Z Gerhart-Hines, H Meziane, … - Cell, 2006 - Elsevier Diminished mitochondrial oxidative phosphorylation and aerobic capacity are associated with
reduced longevity. We tested whether resveratrol (RSV), which is known to extend lifespan, impacts
mitochondrial function and metabolic homeostasis. Treatment of mice with RSV ... Cited by 416 - Related articles - All 20 versions
- ►uc.pt [PDF] AP Rolo, CM Palmeira - Toxicology and applied pharmacology, 2006 - Elsevier Hyperglycemia resulting from uncontrolled glucose regulation is widely recognized as the causal
link between diabetes and diabetic complications. Four major molecular mechanisms have been
implicated in hyperglycemia-induced tissue damage: activation of protein kinase C (PKC) ... Cited by 120 - Related articles - All 7 versions
- ►cell.com TR Koves, JR Ussher, RC Noland, D Slentz, M … - Cell metabolism, 2008 - Elsevier Previous studies have suggested that insulin resistance develops secondary to diminished fat
oxidation and resultant accumulation of cytosolic lipid molecules that impair insulin
signaling. Contrary to this model, the present study used targeted metabolomics to find ... Cited by 120 - Related articles - All 9 versions
- ►aspetjournals.org NG Abraham, A Kappas - Pharmacological reviews, 2008 - ASPET This review is intended to stimulate interest in the effect of increased expression of heme
oxygenase-1 (HO-1) protein and increased levels of HO activity on normal and pathological
states. The HO system includes the heme catabolic pathway, comprising HO and ... Cited by 89 - Related articles - All 6 versions
- ►nih.gov R Boushel, E Gnaiger, P Schjerling, M Skovbro, R … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Insulin resistance and type 2 diabetes are associated with mitochondrial
dysfunction. The aim of the present study was to test the hypothesis that oxidative phosphorylation
and electron transport capacity are dimin- ished in the skeletal muscle of type 2 diabetic ... Cited by 80 - Related articles - BL Direct - All 9 versions
- ►nih.gov A Valerio, A Cardile, V Cozzi, R Bracale, L … - Journal of Clinical …, 2006 - Am Soc Clin Investig 1 Integrated Laboratories Network, Center for Study and Research on Obesity, Department of
Pharmacology, School of Medicine, University of Milan, Milan, Italy. 2 Department of Preclinical
Sciences, University of Milan, Milan, Italy. 3 CEINGE Biotecnologie Avanzate, Naples, ... Cited by 63 - Related articles - BL Direct - All 9 versions
N Turner, CR Bruce, SM Beale, KL Hoehn, T So, MS … - Diabetes, 2007 - Am Diabetes Assoc A reduced capacity for mitochondrial fatty acid oxidation in skeletal muscle has been proposed
as a major factor leading to the accumulation of intramuscular lipids and their subsequent deleterious
effects on insulin action. Here, we examine markers of mitochondrial fatty acid oxidative ... Cited by 63 - Related articles - BL Direct - All 5 versions
C Bonnard, A Durand, S Peyrol, E … - The Journal of …, 2008 - pubmedcentral.nih.gov Mitochondrial dysfunction in skeletal muscle has been implicated in the development of type
2 diabetes. However, whether these changes are a cause or a consequence of insulin resistance
is not clear. We investigated the structure and function of muscle mitochondria during the ... Cited by 53 - Related articles - BL Direct - All 8 versions
KJ Bough, J Wetherington, B Hassel, JF Pare, … - Annals of …, 2006 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 46 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org E Nisoli, E Clementi, MO Carruba, S Moncada - Circulation research, 2007 - Am Heart Assoc The metabolic syndrome is a group of risk factors of metabolic origin that are accompanied by
increased risk for type 2 diabetes mellitus and cardiovascular disease. These risk factors include
atherogenic dyslipidemia, elevated blood pressure and plasma glucose, and a ... Cited by 47 - Related articles - All 6 versions
