AC Rutledge, K Adeli - Nutrition reviews, 2007 - ingentaconnect.com Emerging evidence suggests that increased dietary consumption of fructose in
Western society may be a potentially important factor in the growing rates of
obesity and the metabolic syndrome. This review will discuss ... Cited by 31 - Related articles - BL Direct - All 4 versions
M Vinciguerra, M Foti - Archives of physiology and biochemistry, 2006 - informahealthcare.com Insulin resistance in peripheral tissues is the primary cause responsible for
onset of type II diabetes mellitus. Recently, the genetic and biochemical
dissection of intracellular signalling pathways transducing the metabolic ... Cited by 23 - Related articles - BL Direct - All 8 versions
M Vinciguerra, C Veyrat–Durebex, MA Moukil, … - Gastroenterology, 2007 - Elsevier Background & Aims: Phosphatase and tensin homologue deleted on chromosome 10
(PTEN) is a tumor suppressor and a regulator of insulin sensitivity in
peripheral tissues. In the liver, PTEN deletion increases insulin ... Cited by 19 - Related articles - All 26 versions
A Suzuki, T Nakano, TW Mak, T Sasaki - Cancer Science, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 20 - Related articles - BL Direct - All 3 versions
D Blero, B Payrastre, S Schurmans, C Erneux - Pflügers Archiv European Journal of Physiology, 2007 - Springer Abstract Phosphoinositide phosphatases dephosphorylate the three positions (D-3,
4 and 5) of the inositol ring of the poly-phosphoinositides. They belong to
different families of enzymes. The PtdIns(3,4)P 2 4-phosphatase family, the ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►nih.gov FM Smith, LJ Holt, AS Garfield, M … - Molecular and Cellular Biology, 2007 - Am Soc Microbiol The Grb10 adapter protein is capable of interacting with a variety of receptor
tyrosine kinases, including, notably, the insulin receptor. Biochemical and cell
culture experiments have indicated that Grb10 might act as an inhibitor of ... Cited by 9 - Related articles - BL Direct - All 10 versions
T Rowe, C Hale, A Zhou, RJM Kurzeja, A Ali, … - Assay and Drug Development Technologies, 2006 - liebertonline.com Abstract: SH2 domain-containing inositol 5-phosphatase 2 (SHIP2) is a potential
drug target for the treatment of type 2 diabetes. This enzyme serves as a
negative regulator of insulin-mediated signal transduction by catalyzing ... Cited by 6 - Related articles - BL Direct - All 3 versions
S Onnockx, J De Schutter, M Blockmans, J Xie … - Journal of Cellular Physiology, 2008 - interscience.wiley.com SHIP2 (SH2-containing inositol polyphosphate 5-phosphatase 2) is a
phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P 3 ) 5-phosphatase
containing various motifs susceptible to mediate protein-protein ... Cited by 6 - Related articles - BL Direct - All 2 versions
- ►nih.gov T Ijuin, YE Yu, K Mizutani, A Pao, S Tateya, … - Molecular and Cellular Biology, 2008 - Am Soc Microbiol Insulin controls glucose homeostasis and lipid metabolism, and insulin
impairment plays a critical role in the pathogenesis of diabetes mellitus. Human
skeletal muscle and kidney enriched inositol polyphosphate phosphatase ... Cited by 6 - Related articles - All 6 versions
J Zhang, Z Liu, J Rasschaert, D Blero, L … - Cellular Signalling, 2007 - Elsevier Reactive oxygen species (ROS) are known to be involved in redox signalling
pathways that may contribute to normal cell function as well as disease
progression. The tumour suppressor PTEN and the inositol 5-phosphatase ... Cited by 4 - Related articles - All 3 versions
