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Scholar Results 1 - 10 of about 20 citing Riedel: Saturated and cis/trans unsaturated acyl CoA esters differentially regulate wild-type.... (0.09 sec) 

A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic …

- jbc.org
YW Lin, C MacMullen, A Ganguly, CA Stanley … - Journal of Biological Chemistry, 2006 - ASBMB
The -cell ATP-sensitive potassium (K ATP ) channel controls insulin secretion by
linking glucose metabolism to membrane excitability. Loss of K ATP channel
function due to mutations in ABCC8 or KCNJ11, genes that encode the ...
Cited by 34 - Related articles - BL Direct - All 6 versions

Type 2 diabetes–associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S …

- diabetesjournals.org
JC Florez, KA Jablonski, SE Kahn, PW … - Diabetes, 2007 - Am Diabetes Assoc
The common polymorphisms KCNJ11 E23K and ABCC8 A1369S have been consistently
associated with type 2 diabetes. We examined whether these variants are also
associated with progression from impaired glucose tolerance (IGT) to ...
Cited by 32 - Related articles - BL Direct - All 4 versions

Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: …


JC Florez - Diabetologia, 2008 - Springer
Abstract Although type 2 diabetes has been traditionally understood as a
metabolic disorder initiated by insulin resistance, it has recently become
apparent that an impairment in insulin secretion contributes to its mani- ...
Cited by 31 - Related articles - BL Direct - All 3 versions

ABCC8 and ABCC9: ABC transporters that regulate K+ channels

- pubget.com [PDF] 
J Bryan, A Muñoz, X Zhang, M Düfer, G Drews … - Pflügers Archiv European Journal of Physiology, 2007 - Springer
Abstract The sulfonylurea receptors (SURs) ABCC8/ SUR1 and ABCC9/SUR2 are
members of the C-branch of the transport adenosine triphosphatase superfamily.
Unlike their brethren, the SURs have no identified transport function; ...
Cited by 31 - Related articles - BL Direct - All 6 versions

Metabolic regulation of sodium–calcium exchange by intracellular acyl CoAs


MJ Riedel, I Baczkó, GJ Searle, N Webster, M … - The EMBO Journal, 2006 - pubmedcentral.nih.gov
The sodium–calcium exchanger (NCX) is a critical mediator of calcium
homeostasis. In the heart, NCX1 predominantly operates in forward mode to
extrude Ca 2+ ; however, reverse-mode NCX1 activity during ...
Cited by 11 - Related articles - BL Direct - All 8 versions

Nitro-fatty Acid Metabolome: Saturation, Desaturation,{beta}-Oxidation, and Protein …


V Rudolph, FJ Schopfer, NKH Khoo, TK … - Journal of Biological Chemistry, 2009 - ASBMB
Nitrated derivatives of fatty acids (NO 2 -FA) are pluripotent cell-signaling
mediators that display anti-inflammatory properties. Current understanding of NO
2 -FA signal transduction lacks insight into how or if NO 2 -FA are ...
Cited by 9 - Related articles - All 3 versions

Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid …

- uc.pt [PDF] 
E Nunes, F Peixoto, T Louro, CM Sena, MS … - Acta Diabetologica, 2007 - Springer
Abstract We investigated the effect of sub-chronic soy- bean oil (SO) treatment
on the insulin secretion and fatty acid composition of islets of Langerhans
obtained from Goto-Kakizaki (GK), a model of type 2 diabetes, and nor- mal ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Glucose-induced de novo synthesis of fatty acyls causes proportional increases in INS-1E …


HK Nyblom, LI Nord, R Andersson, L Kenne, … - NMR in biomedicine, 2008 - interscience.wiley.com
Raised concentrations of glucose for extended periods of time have detrimental
effects on the insulin-producing -cell. As de novo synthesis of lipids has been
observed under such conditions, it was hypothesized that newly formed ...
Cited by 4 - Related articles - BL Direct - All 2 versions

Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations …

- nih.gov
YW Lin, JD Bushman, FF Yan, S Haidar, C … - Journal of Biological Chemistry, 2008 - ASBMB
The inwardly rectifying potassium channel Kir6.2 is the pore-forming subunit of
the ATP-sensitive potassium (K ATP ) channel, which controls insulin secretion
by coupling glucose metabolism to membrane potential in β-cells. Loss of ...
Cited by 4 - Related articles - All 4 versions

Modulation of hSlo BK current inactivation by fatty acid esters of CoA


X Sun, H Yao, D Zhou, X Gu, GG Haddad - Journal of Neurochemistry, 2008 - interscience.wiley.com
Lipid metabolism influences membrane proteins, including ion channels, in health
and disease. Fatty acid esters of CoA are important intermediates in fatty acid
metabolism and lipid biosynthesis. In the present study, we examined the ...
Cited by 3 - Related articles - BL Direct - All 3 versions


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