- ►ucla.edu [PDF] JJ MEIER, A BHUSHAN, PC BUTLER - Pediatric research, 2006 - journals.lww.com Both type 1 and type 2 diabetes are characterized by a marked deficit in beta-cell mass causing
insufficient insulin secretion. Beta-cell replacement strategies may eventually provide a cure
for diabetes. Current therapeutic approaches include pancreas and islet transplantation, ... Cited by 33 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org G Parnaud, E Hammar, DG Rouiller, M Armanet, PA … - Diabetes, 2006 - Am Diabetes Assoc When attached on a matrix produced by a rat bladder carcinoma cell line (804G matrix), rat pancreatic
β-cells spread in response to glucose and secrete more insulin compared with cells attached
on poly-l-lysine. The aim of this study was to determine whether laminin-5 and its ... Cited by 22 - Related articles - BL Direct - All 5 versions
… , RT Rodriguez, GW McLean, SK Kim - Proceedings of the …, 2007 - National Acad Sciences Prospective isolation and characterization of progenitor cells is a paradigmatic strategy for studies
of organ development. However, extraction of viable cells, fractionation of lineages, and in vitro
analysis of progenitors from the fetal pancreas in experimental organisms like mice has ... Cited by 24 - Related articles - BL Direct - All 8 versions
JG Lees, SA Lim, T Croll, G Williams, S Lui, J … - Regenerative …, 2007 - Future Medicine Figure 1.3D cell culturing and transplantation procedure. ... (A) Alkaline phosphatase staining
of hESC colonies. (B)Stage-specific embryonic antigen-4 immunostaining of hESC colony.
(C–D) Scanning electron microscopy (SEM) images of unseeded PLGA scaffolds. (E) ... Cited by 17 - Related articles - BL Direct - All 4 versions
BM Lyttle, J Li, M Krishnamurthy, F Fellows, MB … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Morphological changes that occur during pancreatic endocrine cell
differentiation have been shown in rodent systems to be dependent on sequential alterations
in transcription factor expression. However, similar data for humans have been limited. ... Cited by 11 - Related articles - BL Direct - All 2 versions
K Brands, E Colvin, LJ Williams, R Wang, RB Lock, BE … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The use of human fetal pancreatic tissue may provide a potential source of transplantable
β-cells as a therapy for type 1 diabetes. Human fetal pancreas has a remarkable capacity to grow
and differentiate in vivo and has been shown to reverse diabetes in rodents. However, it ... Cited by 7 - Related articles - BL Direct - All 4 versions
I Virtanen, M Banerjee, J Palgi, O Korsgren, A Lukinius, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Based on mouse study findings, pancreatic islet cells are supposed
to lack basement membrane (BM) and interact directly with vascular endothelial BM. Until
now, the BM composition of human islets has remained elusive. Methods ... Cited by 7 - Related articles - BL Direct - All 3 versions
- ►physiology.org J Li, J Quirt, HQ Do, K Lyte, F Fellows, CG … - American Journal of …, 2007 - Am Physiological Soc The receptor, c-Kit, and its ligand, stem cell factor (SCF), are critical for hematopoietic stem cell
differentiation and have been implicated in the development, function, and survival of rodent
islets. Previously, we reported that exogenous SCF treatments of cultured human fetal ... Cited by 6 - Related articles - BL Direct - All 5 versions
- ►nih.gov LM Weber, KS Anseth - Matrix Biology, 2008 - Elsevier The individual and synergistic effects of extracellular matrix interactions on isolated islet function
in culture were investigated within a three-dimensional poly(ethylene glycol) (PEG) hydrogel
encapsulation environment. First, we observed similar glucose-stimulated insulin ... Cited by 3 - Related articles - All 3 versions
- ►nih.gov M Krishnamurthy, J Li, M Al-Masri, R Wang - Journal of Cell Communication …, 2008 - Springer Abstract Integrin-extracellular matrix interactions are im- portant determinants of beta cell
behaviours. The β1 integrin is a well-known regulator of beta cell activities; however, little is known
of its associated α subunits. In the present study, αβ1 integrin expression was examined ... Cited by 2 - Related articles - All 3 versions
