- ►nih.gov [PDF] TA Kinard, G De Vries, A Sherman, LS Satin - Biophysical journal, 1999 - Elsevier Glucose triggers bursting activity in pancreatic islets, which mediates the Ca 2+ uptake that triggers
insulin secretion. Aside from the channel mechanism responsible for bursting, which remains
unsettled, it is not clear whether bursting is an endogenous property of individual β-cells ... Cited by 58 - Related articles - BL Direct - All 12 versions
- ►rupress.org M Braun, A Wendt, J Karanauskaite, J … - Journal of General …, 2007 - jgp.rupress.org The release of -aminobutyric acid (GABA) and ATP from rat ß cells was monitored using an electrophysiological
assay based on overexpression GABA A or P 2 X 2 receptor ion channels. Exocytosis of
LDCVs, detected by carbon fiber amperometry of serotonin, correlated strongly ( 80%) ... Cited by 15 - Related articles - BL Direct - All 8 versions
PE MacDonald, P Rorsman - Physiology (Bethesda, Md.), 2007 - ncbi.nlm.nih.gov Exocytosis of insulin-containing secretory vesicles in pancreatic beta-cells is crucial to maintenance
of plasma glucose levels. They fuse with the plasma membrane in a regulated manner to release
their contents and are subsequently recaptured either intact or through conventional ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►endojournals.org E Grapengiesser, A Salehi, SS Qader, B Hellman - Endocrinology, 2006 - Endocrine Soc Both increase of the glucose concentration and activation of purinoceptors are known to affect
pancreatic -cells. Effects obtained with various purino derivatives at 2.8 and 8.3 mmol/liter glucose
have been taken to indicate that external ATP is less potent than adenosine as a ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►nih.gov I Novak - Purinergic Signalling, 2008 - Springer Abstract The pancreas is a complex gland performing both endocrine and exocrine
functions. In recent years there has been increasing evidence that both endocrine and exocrine
cells possess purinergic receptors, which influence processes such as insulin secretion ... Cited by 8 - Related articles - All 4 versions
A Salehi, SS Qader, E Grapengiesser, B Hellman - Regulatory Peptides, 2007 - Elsevier It was early proposed that somatostatin-producing δ-cells in pancreatic islets have local inhibitory
effects on the release of insulin and glucagon. Recent observations that pulses of insulin and
glucagon are antisynchronous make it important to examine the temporal characteristics ... Cited by 4 - Related articles - All 3 versions
- ►physiology.org E Tuduri, E Filiputti, EM Carneiro, I … - American Journal of …, 2008 - Am Physiological Soc Glucagon secreted from pancreatic -cells plays a critical role in glycemia, mainly by hepatic glucose
mobilization. In diabetic patients, an impaired control of glucagon release can worsen glucose
homeostasis. Despite its importance, the mechanisms that regulate its secretion are still ... Cited by 2 - Related articles - BL Direct - All 3 versions
- ►cell.com M Zhang, B Fendler, B Peercy, P Goel, R Bertram, A … - Biophysical Journal, 2008 - Elsevier Individual mouse pancreatic islets exhibit oscillations in [Ca 2+ ] i and insulin secretion in response
to glucose in vitro, but how the oscillations of a million islets are coordinated within the human
pancreas in vivo is unclear. Islet to islet synchronization is necessary, however, for the ... Cited by 1 - Related articles - All 8 versions
F Parandeh, SM Abaraviciene, S Amisten, D … - … and Biophysical Research …, 2008 - Elsevier Functional in vitro experiments revealed that the P2Y 6 agonist UDPβS dose-dependently enhanced
insulin and glucagon release during short-term incubation (1 h), while P2Y 6 activation during
a longer period (24 h), selectively increased insulin release, especially at high glucose ... Cited by 1 - Related articles - All 3 versions
