- ►diabetesjournals.org K Susztak, AC Raff, M Schiffer, EP Böttinger - Diabetes, 2006 - Am Diabetes Assoc Diabetic nephropathy is the most common cause of end-stage renal disease in the
US Recent studies demonstrate that loss of podocytes is an early feature of
diabetic nephropathy that predicts its progressive course. Cause and ... Cited by 164 - Related articles - BL Direct - All 7 versions
PA Sarafidis, GL Bakris - Kidney international, 2006 - nature.com The global epidemic of diabetes mellitus has led to a continuous increase in the
prevalence of diabetic nephropathy over the past years. Thus, diabetic
nephropathy is currently the number one cause of end-stage renal disease in ... Cited by 72 - Related articles - BL Direct - All 4 versions
PA Sarafidis, LM Ruilope - Am J Nephrol, 2006 - content.karger.com Most of the basic components of the metabolic syndrome, namely type 2 diabetes
mellitus, hypertension, obesity, or low high-density lipoprotein cholesterol
levels, apart from being major risk factors for cardiovascular disease have ... Cited by 66 - Related articles - BL Direct - All 5 versions
- ►shouxi.net PJ Beisswenger, KS Drummond, RG Nelson, … - Diabetes, 2005 - Am Diabetes Assoc Dicarbonyl and oxidative stress may play important roles in the development of
diabetes complications, and their response to hyperglycemia could determine
individual susceptibility to diabetic nephropathy. This study examines the ... Cited by 44 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org C Szabó, A Biser, R Benkő, E Böttinger, K … - Diabetes, 2006 - Am Diabetes Assoc The activation of the poly(ADP-ribose) polymerase (PARP) plays an important role
in the pathophysiology of various diseases associated with oxidative stress. We
found increased amounts of poly(ADP) ribosylated proteins in diabetic ... Cited by 35 - Related articles - BL Direct - All 6 versions
- ►asnjournals.org ML Caramori, P Fioretto, M Mauer - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Diabetic nephropathy (DN) is a growing cause of ESRD despite widely known
recommendations for improved glycemic and BP control. Perhaps earlier
identification of patients who have diabetes and are at high risk for DN ... Cited by 30 - Related articles - BL Direct - All 5 versions
- ►nih.gov P Fioretto, M Mauer - Seminars in nephrology, 2007 - Elsevier The clinical manifestations of diabetic nephropathy, proteinuria, increased
blood pressure, and decreased glomerular filtration rate, are similar in type 1
and type 2 diabetes; however, the renal lesions underlying renal ... Cited by 21 - Related articles - All 9 versions
- ►asnjournals.org IH de Boer, SD Sibley, B Kestenbaum, JN … - Journal of the American Society of Nephrology, 2007 - Am Soc Nephrol Weight gain and central obesity are associated with insulin resistance,
hypertension, and dyslipidemia in type 1 diabetes. These metabolic abnormalities
are risk factors for kidney disease in the general population, but data ... Cited by 17 - Related articles - BL Direct - All 10 versions
P Palatini, P Mormino, F Dorigatti, M … - Kidney international, 2006 - nature.com Factors related to the development of microalbuminuria in hypertension are not
well known. We did a prospective study to investigate whether glomerular
hyperfiltration precedes the development of microalbuminuria in ... Cited by 16 - Related articles - BL Direct - All 4 versions
S Dronavalli, I Duka, GL Bakris… - Nat Clin Pract Endocrinol Metab, 2008 - mp.medscape.com Between 20% and 40% of patients with diabetes ultimately develop diabetic
nephropathy, which in the US is the most common cause of endstage renal disease
requiring dialysis. Diabetic nephropathy has several distinct phases of ... Cited by 16 - Related articles - Cached - All 6 versions
