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Scholar Results 1 - 10 of about 46 citing Detaille: Metformin prevents high-glucose–induced endothelial cell death through a mitochondria.... (0.10 sec) 

Mitochondrial membrane permeabilization in cell death

- physiology.org
G Kroemer, L Galluzzi, C Brenner - Physiological reviews, 2007 - Am Physiological Soc
Irrespective of the morphological features of end-stage cell death (that may be
apoptotic, necrotic, autophagic, or mitotic), mitochondrial membrane
permeabilization (MMP) is frequently the decisive event that delimits the ...
Cited by 337 - Related articles - BL Direct - All 5 versions

Pharmacological and clinical aspects of heme oxygenase

- aspetjournals.org
NG Abraham, A Kappas - Pharmacological reviews, 2008 - ASPET
This review is intended to stimulate interest in the effect of increased
expression of heme oxygenase-1 (HO-1) protein and increased levels of HO
activity on normal and pathological states. The HO system includes the heme ...
Cited by 89 - Related articles - All 6 versions

Endothelial mitochondria: contributing to vascular function and disease

- ahajournals.org
SM Davidson, MR Duchen - Circulation research, 2007 - Am Heart Assoc
Disturbances in vascular function contribute to the development of several
diseases of increasing prevalence and thereby contribute significantly to human
mortality and morbidity. Atherosclerosis, diabetes, heart failure, and ...
Cited by 44 - Related articles - All 7 versions

Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C …

- jbc.org
MA Di Noia, S Van Driesche, F Palmieri, LM … - Journal of Biological Chemistry, 2006 - ASBMB
Up-regulation of heme oxygenase (HO-1) by either cobalt protoporphyrin (CoPP) or
human gene transfer improves vascular and renal function by several mechanisms,
including increases in antioxidant levels and decreases in reactive oxygen ...
Cited by 34 - Related articles - BL Direct - All 4 versions

AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin- …

- physiology.org
L Bertrand, A Ginion, C Beauloye, AD Hebert … - American Journal of Physiology- Heart and Circulatory …, 2006 - Am Physiological Soc
Diabetic hearts are known to be more susceptible to ischemic disease.
Biguanides, like metformin, are known antidiabetic drugs that lower blood
glucose concentrations by decreasing hepatic glucose production and ...
Cited by 31 - Related articles - BL Direct - All 3 versions

Neuronal apoptosis in neurodegeneration


M Okouchi, O Ekshyyan, M Maracine, TY Aw - Antioxidants & Redox Signaling, 2007 - liebertonline.com
Page 1. ANTIOXIDANTS & REDOX SIGNALING Volume 9, Number 8, 2007 © Mary Ann Liebert,
Inc. DOI: 10.1089/ars.2007.1511 Comprehensive Invited Review ...
Cited by 31 - Related articles - BL Direct - All 4 versions

The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is …


C Batandier, B Guigas, D Detaille, M El-Mir, … - Journal of bioenergetics and biomembranes, 2006 - Springer
Page 1. J Bioenerg Biomembr (2006) 38:33–42 DOI 10.1007/s10863-006-9003-8 ORIGINAL
PAPER The ROS production induced by a reverse-electron flux at ...
Cited by 26 - Related articles - BL Direct - All 3 versions

Effects of NO on mitochondrial function in cardiomyocytes: pathophysiological relevance

- cardiovascres.org
SM Davidson, MR Duchen - Cardiovascular research, 2006 - cardiovascres.org
Although the specific roles of nitric oxide (NO) in the heart in general and on
cardiac mitochondria in particular remain controversial, it is now clear that
both endogenous and exogenous sources of NO exert important modulatory ...
Cited by 26 - Related articles - All 6 versions

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a …


IB Sahra, K Laurent, A Loubat, S Giorgetti- … - Oncogene, 2008 - nature.com
Metformin is a widely used antidiabetic agent, which regulates glucose
homeostasis through inhibition of liver glucose production and an increase in
muscle glucose uptake. Recent studies suggest that metformin may reduce the ...
Cited by 25 - Related articles - BL Direct - All 4 versions

AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative …


B Guigas, N Taleux, M Foretz, D Detaille, F … - The Biochemical journal, 2007 - pubmedcentral.nih.gov
AICA riboside (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) has been
extensively used in cells to activate the AMPK (AMP-activated protein kinase), a
metabolic sensor involved in cell energy homoeostasis. In the present ...
Cited by 20 - Related articles - BL Direct - All 7 versions


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