- ►physiology.org JF Oram, JW Heinecke - Physiological reviews, 2005 - Am Physiological Soc Blood high-density lipoprotein (HDL) levels are inversely related to risk for cardiovascular
disease, implying that factors associated with HDL metabolism are atheroprotective. One of these
factors is ATP-binding cassette transporter A1 (ABCA1), a cell membrane protein that ... Cited by 156 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org JF Oram, AM Vaughan - Circulation research, 2006 - Am Heart Assoc A hallmark of atherosclerotic cardiovascular disease (CVD) is the accumulation of cholesterol
in arterial macrophages. Factors that modulate circulating and tissue cholesterol levels have
major impacts on initiation, progression, and regression of CVD. Four members of the ... Cited by 105 - Related articles - All 8 versions
- ►ahajournals.org JE Kanter, F Johansson, RC LeBoeuf, KE … - Circulation research, 2007 - Am Heart Assoc It is becoming increasingly clear that suboptimal blood glucose control results in adverse effects
on large blood vessels, thereby accelerating atherosclerosis and cardiovascular disease, manifested
as myocardial infarction, stroke, and peripheral vascular disease. Cardiovascular disease ... Cited by 33 - Related articles - All 8 versions
- ►jbc.org JP Mauldin, S Srinivasan, A Mulya, A Gebre, JS … - Journal of Biological …, 2006 - ASBMB Atherosclerosis development is accelerated severalfold in patients with Type 2 diabetes. In the
initial stages of disease, monocytes transmigrate into the subendothelial space and differentiate
into foam cells. Scavenger receptors and ATP binding cassette (ABC) Transporters play ... Cited by 22 - Related articles - BL Direct - All 6 versions
A Hoang, AJ Murphy, MT Coughlan, MC Thomas, JM … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis AGE contribute to the pathogenesis of diabetic complications, including
dyslipidaemia and athero- sclerosis. However, the precise mechanisms remain to be
established. In the present study, we examined whether AGE modification of ... Cited by 19 - Related articles - BL Direct - All 4 versions
- ►fasebj.org AV Cantero, M Portero-Otin, V Ayala, N Auge, M … - The FASEB Journal, 2007 - FASEB Purpose: Low molecular weight carbonyl compounds, such as the -ketoaldehydes methylglyoxal
(MGO) and glyoxal (GO), are formed under hyperglycemic conditions and behave as advanced
glycation end product (AGE) precursors. They form adducts on proteins, thereby inducing ... Cited by 15 - Related articles - BL Direct - All 3 versions
LR Brunham, JK Kruit, CB Verchere, MR … - The Journal of Clinical …, 2008 - pubmedcentral.nih.gov Type 2 diabetes (T2D) frequently occurs in the context of abnormalities of plasma
lipoproteins. However, a role for elevated levels of plasma cholesterol in the pathogenesis of
this disease is not well established. Recent evidence suggests that alterations of plasma ... Cited by 11 - Related articles - BL Direct - All 6 versions
I Goldiner, AE van der Velde, KE … - Biochemical …, 2006 - pubmedcentral.nih.gov FABACs (fatty acid–bile acid conjugates) are synthetic molecules that are designed to treat a
range of lipid disorders. The compounds prevent cholesterol gallstone formation and diet-induced
fatty liver, and increase reverse cholesterol transport in rodents. The aim of the present ... Cited by 9 - Related articles - BL Direct - All 11 versions
D Conklin, R Prough, A Bhatanagar - Molecular BioSystems, 2007 - rsc.org Daniel J. Conklin, PhD, was born in 1964 in Menomonie, Wisconsin. He received a BS in Biology
from the University of Wisconsin-Whitewater (1986), a MS in Biology (1989) from the University
of Wisconsin-LaCrosse, and a PhD in Biology from University of Notre Dame (1995). He ... Cited by 8 - Related articles - Cached - BL Direct - All 3 versions
GH Tomkin - Diabetes care, 2008 - Am Diabetes Assoc Treatment for dyslipidemia in diabetes reduces cardiovascular events. Diabetes is associated
with major abnormalities in fatty acid metabolism. The resulting disturbance results in an abnormal
lipoprotein cascade from the large chylomicron through to the small HDL particle. This ... Cited by 6 - Related articles - BL Direct - All 6 versions
