PA Sarafidis, GL Bakris - Kidney international, 2006 - nature.com The global epidemic of diabetes mellitus has led to a continuous increase in the prevalence
of diabetic nephropathy over the past years. Thus, diabetic nephropathy is currently the number
one cause of end-stage renal disease in the Western world. It represents a major public ... Cited by 72 - Related articles - BL Direct - All 4 versions
P Ruggenenti, G Remuzzi - Kidney international, 2006 - nature.com The term microalbuminuria – a urinary albumin excretion (UAE) between 20 and 200 g/min –
has been introduced to identify subjects at increased risk of renal and cardiovascular
disease. However, the relationship between albuminuria and risk is not restricted to the ... Cited by 54 - Related articles - BL Direct - All 7 versions
- ►nih.gov M Chakir, GE Plante - Prostaglandins, Leukotrienes & Essential Fatty Acids, 1996 - Elsevier In the present study, we examined the pattern of Evan's blue (EB) extravasation over time and
we verified the effect of two inhibitors of aldose reductase (sorbinil and ARI 509) as well as
aminoguanidine, which modulate nitric oxide (NO) production, on streptozotocin-induced ... Cited by 35 - Related articles - BL Direct - All 12 versions
- ►eje.org P Iglesias, JJ Diez - European Journal of Endocrinology, 2006 - eje.org Type 2 diabetes is a well recognised cause of chronic renal failure (CRF). Only few oral antidiabetic
drugs can be used for treating type 2 diabetes in patients with CRF. Among them are
repaglinide, a rapid-acting prandial insulin releaser, and peroxisome ... Cited by 25 - Related articles - BL Direct - All 7 versions
- ►critcaremed.org C Zoccali - Journal of hypertension, 2006 - journals.lww.com The endogenous inhibitor of the nitric oxide synthase, asymmetric dimethylarginine (ADMA),
by reducing nitric oxide (NO) availability, may trigger pro-atherogenic effects. A high plasma
concentration of this substance has been associated to intima-media thickening, left ... Cited by 24 - Related articles - BL Direct - All 10 versions
CV Rizos, EN Liberopoulos, DP … - Expert Opin. …, 2008 - informahealthcare.com Background: Insulin resistance and hyperglycemia characterize type 2 diabetes mellitus. Type
2 diabetes mellitus is usually accompanied by concomitant disorders, such as dyslipidemia,
hypertension and atherosclerosis. Thiazolidinediones are antidiabetic drugs that increase ... Cited by 18 - Related articles - BL Direct - All 6 versions
- ►oxfordjournals.org GJ Ko, YS Kang, SY Han, MH Lee, HK Song, KH … - Nephrology Dialysis …, 2008 - ERA-EDTA Results. Treatment of OLETF rats with pioglitazone improved insulin sensitivity and kidney/body
weight, but had a little effect on blood pressure. Pioglitazone treatment markedly reduced urinary
albumin and MCP-1 excretion, and ameliorated glomerulosclerosis. In cDNA microarray ... Cited by 14 - Related articles - All 4 versions
- ►asnjournals.org RE Gilbert, K Connelly, DJ Kelly, CA Pollock, … - Clinical Journal of the …, 2006 - Am Soc Nephrol Heart failure (HF) is a major contributor to poor quality of life, a leading cause of
hospitalization, and cause of premature death. Both kidney disease and diabetes are major and
independent risk factors for the development of heart failure, such that individuals with ... Cited by 15 - Related articles - BL Direct - All 5 versions
S Ohtomo, Y Izuhara, S Takizawa, N Yamada, T … - Kidney international, 2007 - nature.com Hyperinsulinemia has been implicated in the development of diabetic nephropathy. In the present
study we compared the renoprotective effects of the thiazolidinedione, pioglitazone (PGZ), to
that of insulin in a hypertensive, obese, type II diabetic rat model. PGZ aggravated obesity ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►critcaremed.org HA Pershadsingh - Treatments in Endocrinology, 2006 - pt.wkhealth.com Peroxisome proliferator-activated receptors (PPARs) are relatively recently discovered nuclear
transcription factors that are modulated by dietary fatty acids, including the essential polyunsaturated
fatty acids, arachidonic acid and its metabolites, and are essential to the control of energy ... Cited by 11 - Related articles - All 5 versions
