- ►jlr.org S Cinti, G Mitchell, G Barbatelli, I Murano, E Ceresi, … - The Journal of Lipid …, 2005 - ASBMB Macrophage infiltration of white adipose tissue (WAT) is implicated in the metabolic complications
of obesity. The precipitating event(s) and function(s) of macrophage infiltration into WAT are
unknown. We demonstrate that >90% ... Cited by 288 - Related articles - BL Direct - All 8 versions
- ►nih.gov CN Lumeng, JL Bodzin, AR Saltiel - Journal of Clinical …, 2007 - Am Soc Clin Investig Adipose tissue macrophages (ATMs) infiltrate adipose tissue during obesity and contribute to insulin
resistance. We hypothesized that macrophages migrating to adipose tissue upon high-fat feeding may
differ from those that reside there ... Cited by 241 - Related articles - BL Direct - All 9 versions
- ►sio-obesita.org [PDF] S Cinti - Prostaglandins, Leukotrienes & Essential Fatty Acids, 2005 - Elsevier In mammals, the adipose tissues are contained in a multi-depot organ: the adipose organ. It consists
of several subcutaneous and visceral depots. Some areas of these depots are brown and correspond to
brown adipose tissue, while many ... Cited by 155 - Related articles - All 16 versions
- ►nih.gov JG Neels, JM Olefsky - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Obesity is associated with increased macrophage infiltration of adipose tissue, and these
macrophages may be an important component of the chronic inflammatory response playing a crucial
role in the development of insulin ... Cited by 119 - Related articles - BL Direct - All 10 versions
- ►endojournals.org ME Trujillo, PE Scherer - Endocrine reviews, 2006 - Endocrine Soc The endocrine functions of the adipose organ are widely studied at this stage. The adipose organ,
and in particular adipocytes, communicate with almost all other organs. Although some adipose tissue
pads assume the functions as ... Cited by 119 - Related articles - BL Direct - All 9 versions
R Cancello, J Tordjman, C Poitou, G Guilhem, JL … - Diabetes, 2006 - Am Diabetes Assoc In human obesity, white adipose tissue (WAT) is enriched in macrophages. How macrophage infiltration
in WAT contributes to the complications of obesity is unknown. This study tested the hypothesis that
recruitment of macrophages in ... Cited by 112 - Related articles - BL Direct - All 5 versions
MC Alessi, I Juhan-Vague - Arteriosclerosis, thrombosis, and vascular …, 2006 - Am Heart Assoc The link between plasminogen activator inhibitor (PAI)-1 and the metabolic syndrome with obesity was
established many years ago. Increased PAI-1 level can be now considered a true component of the
syndrome. The metabolic syndrome is ... Cited by 106 - Related articles - All 9 versions
- ►physiology.org DB Savage, KF Petersen, GI Shulman - Physiological reviews, 2007 - Am Physiological Soc Although abnormal glucose metabolism defines type 2 diabetes mellitus (T2DM) and accounts for many
of its symptoms and complications, efforts to understand the pathogenesis of T2DM are increasingly
focused on disordered lipid ... Cited by 113 - Related articles - BL Direct - All 5 versions
PA Permana, C Menge, PD Reaven - Biochemical and biophysical research …, 2006 - Elsevier Macrophage infiltration into adipose tissue increases with obesity, a condition associated with
low-grade inflammation and insulin resistance. We investigated the direct effects of
macrophage-secreted factors on ... Cited by 106 - Related articles - All 5 versions