H Vlassara - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2005 - interscience.wiley.com Abstract: It is believed that intracellular and extracellular advanced glycation (AGEs) or lipoxidation
end products (ALEs), together with dysregulated glucose and lipid metabolism, are important
contributors to oxidant or carbonyl stress, enhanced cellular redox-sensitive transcription ... Cited by 58 - Related articles - BL Direct - All 5 versions
- ►cnfindpark.cn M Negrean, A Stirban, B Stratmann, T … - American Journal of …, 2007 - ajcn.cnfindpark.cn Design: Twenty inpatients with T2DM [ (±SEM) age: 55.4 ± 2.2 y; glycated hemoglobin: 8.8 ±
0.5%] were investigated. In a randomized crossover design, the effects of a low-AGE (LAGE)
and high-AGE (HAGE) meal on macrovascular [by flow-mediated dilatation (FMD)] and ... Cited by 50 - Related articles - BL Direct - All 7 versions
IA Leclercq, A Da Silva Morais, B Schroyen, N Van Hul, … - Journal of hepatology, 2007 - Elsevier Very few studies have addressed insulin resistance in sinusoidal liver cells. These cells are not
simply bystanders and passive witnesses of the changes affecting the hepatocytes. They are
target cells that will respond to the pathological alterations occurring in the insulin ... Cited by 40 - Related articles - All 6 versions
- ►nih.gov J Uribarri, W Cai, M Peppa, S Goodman, L … - … of Gerontology Series …, 2007 - Geron Soc America Background. Oxidative stress (OS) and inflammatory mediators increase with aging. The levels
of advanced glycation endproducts (AGEs), prooxidant factors linked to chronic diseases such
as diabetes, cardiovascular disease, and renal disease, also increase with aging. AGEs ... Cited by 36 - Related articles - BL Direct - All 5 versions
- ►amjpathol.org W Cai, JC He, L Zhu, X Chen, S Wallenstein, GE … - American Journal of …, 2007 - ASIP Aging is accompanied by increased oxidative stress (OS) and accumulation of advanced glycation
end products (AGEs). AGE formation in food is temperature-regulated, and ingestion of nutrients
prepared with excess heat promotes AGE formation, OS, and cardiovascular disease in ... Cited by 30 - Related articles - BL Direct - All 5 versions
S Yamagishi, S Ueda, S Okuda - Current Pharmaceutical Design, 2007 - ingentaconnect.com Abstract: Non-enzymatic modification of proteins by reducing sugars, a process that is also known
as Maillard reaction, leads to the formation of advanced glycation end products (AGEs) in
vivo. It is now well established that formation and accumulation of AGEs pro- gress during ... Cited by 21 - Related articles - BL Direct - All 2 versions
SM Sweitzer, SA Fann, TK Borg, JW Baynes, MJ … - The Diabetes …, 2006 - tde.sagepub.com From the Department of Surgery (Dr Fann, Dr Yost); the Department of Pharmacology,
Physiology, and Neuroscience (Dr Sweitzer); the Department of Cell and Developmental Biology
and Anatomy (Dr Borg); and the Department of Chemistry and Biochemistry (Dr Baynes), ... Cited by 18 - Related articles - BL Direct - All 3 versions
R Rao, CM Hao, R Redha, DH Wasserman, OP … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis In the current study, the effect of a highly specific peptide inhibitor of
glycogen synthase kinase 3 (GSK3) (L803-mts) on glucose metabolism and BP was examined
in a high-fat (HF) fed mouse model of diabetes. Methods C57/BL6J mice were placed on ... Cited by 17 - Related articles - BL Direct - All 6 versions
H Vlassara, G Striker - Current Diabetes Reports, 2007 - Springer Introduction Elevated advanced glycation end products (AGEs), or gly- cotoxins, have long been
associated with the progression and severity of diabetic complications. Findings from major studies
such as the DCCT (Diabetes Control and Complications Trial) have shown that intensive ... Cited by 14 - Related articles - BL Direct - All 2 versions
- ►amjpathol.org W Cai, JC He, L Zhu, X Chen, F Zheng, GE Striker, H … - American Journal of …, 2008 - ASIP We previously showed that the content of advanced glycation end products (AGEs) in the diet
correlates with serum AGE levels, oxidant stress (OS), organ dysfunction, and lifespan. We now
show that the addition of a chemically defined AGE (methyl-glyoxal-BSA) to low-AGE ... Cited by 13 - Related articles - All 6 versions
