JM Weinberg - Kidney international, 2006 - nature.com Excess fatty acids accompanied by triglyceride accumulation in parenchymal cells
of multiple tissues including skeletal and cardiac myocytes, hepatocytes, and
pancreatic beta cells results in chronic cellular dysfunction and injury. ... Cited by 47 - Related articles - BL Direct - All 3 versions
G Proctor, T Jiang, M Iwahashi, Z Wang, J Li, … - Diabetes, 2006 - Am Diabetes Assoc In Akita and OVE26 mice, two genetic models of type 1 diabetes, diabetic
nephropathy is characterized by mesangial expansion and loss of podocytes,
resulting in glomerulosclerosis and proteinuria, and is associated with ... Cited by 29 - Related articles - BL Direct - All 5 versions
SM Kutz, CE Higgins, R Samarakoon, SP … - Experimental cell research, 2006 - Elsevier Transforming growth factor-β1 (TGF-β1) transcriptionally regulates the
expression of genes that encode specific proteins (eg, plasminogen activator
inhibitor-1; PAI-1) important in stromal remodeling and cellular invasion. ... Cited by 28 - Related articles - All 5 versions
SM Marshall - Current pharmaceutical design, 2007 - ingentaconnect.com Abstract: Over the last five years, much work has underlined the important role
of the podocyte in the development of diabetic neph- ropathy. The metabolic and
haemodynamic abnormalities of the diabetic milieu act in concert, perhaps ... Cited by 25 - Related articles - BL Direct - All 4 versions
M Tozawa, C Iseki, K Tokashiki, S Chinen, K … - Hypertension Research, 2007 - nature.com Metabolic syndrome is a risk factor for the development of cardiovascular
disease. Few prospective studies, however, have examined metabolic syndrome as a
risk factor for chronic kidney disease (CKD) in an Asian population. We ... Cited by 23 - Related articles - BL Direct - All 2 versions
- ►physiology.org [PDF] WE Rodriguez, N Tyagi, IG Joshua, JC … - American Journal of Physiology- Renal Physiology, 2006 - Am Physiological Soc Page 1. Piogiltazone Mitigates Renal Glomerular Vascular Changes in
High-Fat High- Calorie Induced Type 2 Diabetes Mellitus* Walter ... Cited by 19 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org T Jiang, XX Wang, P Scherzer, P Wilson, J … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Recent studies indicate an important role for nuclear receptors in
regulating lipid and carbohydrate metabolism, fibrosis, and inflammation.
Farnesoid X receptor (FXR) is a member of the nuclear hormone receptor ... Cited by 18 - Related articles - BL Direct - All 3 versions
- ►asnjournals.org S Kume, T Uzu, S Araki, T Sugimoto, K … - Journal of the American Society of Nephrology, 2007 - Am Soc Nephrol Metabolic syndrome is associated with increased risk of chronic kidney disease,
and the renal injury in patients with metabolic syndrome may be a result of
altered renal lipid metabolism. We fed wild-type or insulin-sensitive ... Cited by 14 - Related articles - All 6 versions
A Graziani, C Rosker, SD Kohlwein, MX Zhu, … - Biochemical Journal, 2006 - pubmedcentral.nih.gov TRPC3 (canonical transient receptor potential protein 3) has been suggested to
be a component of cation channel complexes that are targeted to cholesterol-rich
lipid membrane microdomains. In the present study, we investigated the ... Cited by 12 - Related articles - BL Direct - All 7 versions
- ►physiology.org [PDF] JH Dominguez, P Wu, CS Packer, CJ Temm, … - American Journal of Physiology- Renal Physiology, 2007 - Am Physiological Soc Page 1. 1 Lipotoxic and inflammatory phenotypes in rats with uncontrolled
metabolic syndrome and nephropathy By Jesus Dominguez, MD ... Cited by 9 - Related articles - BL Direct - All 4 versions
