B Xue, BB Kahn - The Journal of physiology, 2006 - Physiological Soc The evolutionarily conserved serine/threonine kinase, AMP-activated protein kinase
(AMPK), functions as a cellular fuel gauge that regulates metabolic pathways in glucose and
fatty acid metabolism and protein synthesis. Recent data strongly implicate the ... Cited by 70 - Related articles - BL Direct - All 8 versions
- ►jbc.org TL Martin, T Alquier, K Asakura, N Furukawa, F … - Journal of Biological …, 2006 - ASBMB AMP-activated protein kinase (AMPK) is a key regulator of cellular energy balance and of the
effects of leptin on food intake and fatty acid oxidation. Obesity is usually associated with resistance
to the effects of leptin on food intake and body weight. To determine whether diet-induced ... Cited by 53 - Related articles - BL Direct - All 7 versions
- ►jlr.org S Fediuc, MP Gaidhu, RB Ceddia - The Journal of Lipid Research, 2006 - ASBMB The purpose of this study was to investigate the effects of long-chain fatty acids (LCFAs) on
AMP-activated protein kinase (AMPK) and acetyl-coenzyme A carboxylase (ACC) phosphorylation
and ß-oxidation in skeletal muscle. L6 rat skeletal muscle cells were exposed to various ... Cited by 34 - Related articles - BL Direct - All 7 versions
- ►jlr.org G Rizki, L Arnaboldi, B Gabrielli, J Yan, GS Lee, RK … - The Journal of Lipid …, 2006 - ASBMB Lipogenic diets that are completely devoid of methionine and choline (MCD) induce hepatic
steatosis. MCD feeding also provokes systemic weight loss, for unclear reasons. In this
study, we found that MCD feeding causes profound hepatic suppression of the gene ... Cited by 24 - Related articles - BL Direct - All 13 versions
H Makino, Y Miyamoto, K Sawai, K Mori, M … - DIABETES-NEW …, 2006 - Am Diabetes Assoc Glomerular injury plays a pivotal role in the development of diabetic nephropathy. To elucidate
molecular mecha- nisms underlying diabetic glomerulopathy, we compared glomerular gene
expression profiles of db/db mice with those of db/m control mice at a normoalbuminuric ... Cited by 20 - Related articles - BL Direct - All 5 versions
K Reue, J Phan - Current Opinion in Clinical Nutrition & Metabolic Care, 2006 - journals.lww.com Purpose of review: Adipose tissue is a key player in metabolic homeostasis through its role as
an energy depot and endocrine organ. The characterization of mouse models of
lipodystrophy, in which adipose tissue development and function are impaired, has shed ... Cited by 19 - Related articles - BL Direct - All 4 versions
M Barnea, A Shamay, AH Stark, Z Madar - Obesity, 2006 - nature.com Results: Mice fed the HF diet exhibited significantly greater weight gain, abnormal oral glucose
tolerance test curves, and elevated homeostasis model assessment of insulin resistance (5.3
0.89 vs. 2.8 0.39). A significant reduction of adiponectin RNA expression (51% ) and ... Cited by 14 - Related articles - All 3 versions
SL Gray, AJ Vidal-Puig - Nutrition reviews, 2007 - ingentaconnect.com Adipose tissue expands to accommodate increased lipid through hypertrophy of existing adipocytes
and by initiating differentiation of preadipocytes. The ca- pacity of adipose tissue to expand is
critical for accommodating changes in energy availability, but this capacity is not an ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►cell.com R Lage, C Diéguez, A Vidal-Puig, M López - Trends in Molecular Medicine, 2008 - Elsevier AMP-activated protein kinase (AMPK) is the downstream component of a kinase cascade that
acts as a gauge of cellular energy levels. Over the last few years, accumulating evidence has
demonstrated that AMPK is also involved in the regulation of energy balance at the whole- ... Cited by 14 - Related articles - All 7 versions
S Arora - Diabetes, Obesity and Metabolism, 2008 - ingentaconnect.com Obesity results from an abnormal accumulation of fat in the white adipose tissue. Recent research
utilizing genetic models of obesity in rodents has implicated a major role of leptin as a controller
of obesity. Leptin is a 167-amino acid peptide hormone encoded by the obesity gene ... Cited by 7 - Related articles
