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Scholar Results 1 - 10 of 10 citing Fauconnier: Insulin and inositol 1, 4, 5-trisphosphate trigger abnormal cytosolic Ca2+ transients.... (0.11 sec) 

IP3 receptor-dependent Ca2+ release modulates excitation-contraction coupling in …

- physiology.org
TL Domeier, AV Zima, JT Maxwell, S Huke … - American Journal of …, 2008 - Am Physiological Soc
Inositol 1,4,5-trisphosphate (IP 3 ) receptor (IP 3 R)-dependent Ca 2+ signaling exerts positive
inotropic, but also arrhythmogenic, effects on excitation-contraction coupling (ECC) in the atrial
myocardium. The role of IP 3 R-dependent sarcoplasmic reticulum (SR) Ca 2+ release in ...
Cited by 14 - Related articles - BL Direct - All 3 versions

Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic …


H Bugger - Clinical Science, 2008 - clinsci.org
The metabolic syndrome represents a cluster of abnormalities, including obesity, insulin
resistance, dyslipidaemia and Type 2 diabetes, that increases the risk of developing cardiovascular
diseases, such as coronary artery disease and heart failure. The heart failure risk is ...
Cited by 13 - Related articles - Cached - BL Direct - All 7 versions

Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin- …

- cardiovascres.org
J Fauconnier, JT Lanner, A Sultan, SJ Zhang, … - Cardiovascular …, 2007 - cardiovascres.org
Results: Application of the membrane permeable DAG analogue (OAG, 30 µM) induced an
NSCC, which was 40% smaller in ob/ob than in WT cardiomyocytes. Insulin induced a small
NSCC with similar amplitude in ob/ob and WT cells. Pretreatment with insulin (60 nM) ...
Cited by 13 - Related articles - All 8 versions

Effects of Palmitate on Ca2+ Handling in Adult Control and ob/ob Cardiomyocytes


J Fauconnier, DC Andersson, SJ Zhang, JT Lanner, R … - Diabetes, 2007 - Am Diabetes Assoc
Obesity and insulin resistance are associated with enhanced fatty acid utilization, which may
play a central role in diabetic cardiomyopathy. We now assess the effect of the saturated fatty
acid palmitate (1.2 mmol/l) on Ca 2+ handling, cell shortening, and mitochondrial ...
Cited by 12 - Related articles - BL Direct - All 5 versions

The role of Ca2+ influx for insulin-mediated glucose uptake in skeletal muscle


JT Lanner, A Katz, P Tavi, ME Sandström, SJ Zhang, C … - Diabetes, 2006 - Am Diabetes Assoc
The involvement of Ca 2+ in insulin-mediated glucose uptake is uncertain. We measured Ca
2+ influx (as Mn 2+ quenching or Ba 2+ influx) and 2-deoxyglucose (2-DG) uptake in single muscle
fibers isolated from limbs of adult mice; 2-DG uptake was also measured in isolated ...
Cited by 11 - Related articles - BL Direct - All 5 versions

Emerging roles of inositol 1, 4, 5-trisphosphate signaling in cardiac myocytes

- nih.gov
J Kockskämper, AV Zima, HL Roderick, B Pieske, … - Journal of molecular and …, 2008 - Elsevier
Inositol 1,4,5-trisphosphate (IP 3 ) is a ubiquitous intracellular messenger regulating diverse
functions in almost all mammalian cell types. It is generated by membrane receptors that couple
to phospholipase C (PLC), an enzyme which liberates IP 3 from phosphatidylinositol 4,5- ...
Cited by 5 - Related articles - All 16 versions

Animal models of catheter-induced intimal hyperplasia in type 1 and type 2 …


… , SN Murthy, AN Fonseca, CV Desouza, … - … of Physiology and …, 2009 - article.pubs.nrc-cnrc.gc.ca
Abstract: Diabetes is a complex disorder characterized by impaired insulin formation, release
or action (insulin resist- ance), elevated blood glucose, and multiple long-term
complications. It is a common endocrine disorder of humans and is associated with ...
Cited by 1 - Related articles - All 4 versions

Mice expressing L345P mutant desmin exhibit morphological and functional …


A Kostareva, G Sjöberg, J Bruton, SJ Zhang, J … - Journal of Muscle …, 2008 - Springer
Abstract Desmin mutations underlie inherited myopa- thies/cardiomyopathies with varying severity
and involvement of the skeletal and cardiac muscles. We developed a trans- genic mouse model
expressing low level of the L345P desmin mutation (DESMUT mice) in order to uncover ...
Related articles - All 2 versions

[PDF] Impact of Mitochondrial Reactive Oxygen Species


J Fauconnier, DC Andersson, SJ Zhang, JT Lanner, R … - DIABETES, 2007 - Am Diabetes Assoc
Jérémy Fauconnier, 1 Daniel C. Andersson, 1 Shi-Jin Zhang, 1 Johanna T. Lanner, 1 Rolf
Wibom, 2 ... Abram Katz, 1 Joseph D. Bruton, 1 and Håkan Westerblad 1 ... Obesity and insulin
resistance are associated with en- hanced fatty acid utilization, which may play a central ...
Related articles - All 2 versions

A New Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J Mice


JT Lanner, A Katz, P Tavi, ME Sandstrm, SJ Zhang, C … - 糖尿病学杂志, 2006 - journal.shouxi.net
The involvement of Ca2+ in insulin-mediated glucose uptake is uncertain. We measured Ca2+
influx (as Mn2+ quenching or Ba2+ influx) and 2-deoxyglucose (2-DG) uptake in single muscle
fibers isolated from limbs of adult mice; 2-DG uptake was also measured in isolated ...
Related articles - Cached


 


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