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Scholar Results 1 - 10 of about 52 citing Gault: Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3).... (0.12 sec) 

Biology of incretins: GLP-1 and GIP

- rh.dk [PDF] 
LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier
This review focuses on the mechanisms regulating the synthesis, secretion,
biological actions, and therapeutic relevance of the incretin peptides
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like ...
Cited by 173 - Related articles - All 25 versions

The role of gut hormones in glucose homeostasis

- nih.gov
DJ Drucker - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig
The gastrointestinal tract has a crucial role in the control of energy
homeostasis through its role in the digestion, absorption, and assimilation of
ingested nutrients. Furthermore, signals from the gastrointestinal tract ...
Cited by 85 - Related articles - BL Direct - All 11 versions

Emerging therapies mimicking the effects of amylin and glucagon-like peptide 1

- glucagon.com [PDF]  - Free from Publisher
MC Riddle, DJ Drucker - Diabetes Care, 2006 - Am Diabetes Assoc
Current therapies for type 2 diabetes are frequently associated with inadequate
control of postprandial hyperglycemia, weight gain, and, in the case of oral
agents, loss of efficacy over time. A better understanding of physiological ...
Cited by 71 - Related articles - BL Direct - All 10 versions

Adipose tissue as source and target for novel therapies

- adipo-site.net [PDF] 
J Klein, N Perwitz, D Kraus, M Fasshauer - Trends in Endocrinology & Metabolism, 2006 - Elsevier
The physiology of adipose tissue has a key role in the pathogenesis of the
metabolic syndrome and related cardiovascular disorders. Three main functions of
adipocytes have been proposed to explain this role: the secretion of ...
Cited by 33 - Related articles - All 11 versions

GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic …

- physiology.org
PL McClean, N Irwin, RS Cassidy, JJ Holst, VA … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
The gut hormone gastric inhibitory polypeptide (GIP) plays a key role in glucose
homeostasis and lipid metabolism. This study investigated the effects of
administration of a stable and specific GIP receptor antagonist, (Pro 3 ...
Cited by 27 - Related articles - BL Direct - All 3 versions

Early administration of the glucose-dependent insulinotropic polypeptide receptor antagonist …


N Irwin, PL McClean, FPM O'Harte, VA Gault, P … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Ablation of gastric inhibitory polypeptide (GIP)
receptor action is reported to protect against obesity and associated metabolic
abnormalities. The aim of this study was to use prediabetic ob/ob mice to ...
Cited by 26 - Related articles - BL Direct - All 5 versions

Pancreatic and extrapancreatic effects of gastric inhibitory polypeptide

- shouxi.net
Y Yamada, K Miyawaki, K Tsukiyama, N … - Diabetes, 2006 - Am Diabetes Assoc
The hormonal factor(s) implicated as transmitters of signals from the gut to
pancreatic β-cells is referred to as incretin, and gastric inhibitory
polypeptide (GIP) is identified as one of the incretins. GIP is a ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Laparoscopic treatment of type 2 diabetes mellitus for patients with a body mass index less …

- diabetessurgeryindia.com [PDF] 
AL DePaula, ALV Macedo, N Rassi, CA … - Surgical Endoscopy, 2008 - Springer
Abstract Background Type 2 diabetes mellitus (T2DM) is a common disease with
numerous complications. Bariatric surgery is an efficient procedure for
controlling T2DM in morbidly obese patients. In T2DM, the incretin effect ...
Cited by 21 - Related articles - BL Direct - All 4 versions

Differential Antidiabetic Efficacy of Incretin Agonists Versus DPP-4 Inhibition in High Fat– …

- diabetesjournals.org
BJ Lamont, DJ Drucker - Diabetes, 2008 - Am Diabetes Assoc
RESULTS AND CONCLUSIONS— Mice treated with vehicle alone or DA-GIP exhibited
progressive weight gain, whereas treatment with Ex-4 or DPP-4i prevented weight
gain. Although Ex-4 improved oral glucose tolerance and insulin-to-glucose ...
Cited by 17 - Related articles - BL Direct - All 5 versions

Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin …


VA Gault, PL McClean, RS Cassidy, N Irwin, … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Gastric inhibitory polypeptide (GIP) re- ceptor
antagonism with (Pro 3 )GIP improves glucose toler- ance and ameliorates insulin
resistance and abnormalities of islet structure/function in ob/ob mice. ...
Cited by 16 - Related articles - BL Direct - All 4 versions


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