- ►rh.dk [PDF] LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier This review focuses on the mechanisms regulating the synthesis, secretion,
biological actions, and therapeutic relevance of the incretin peptides
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like ... Cited by 173 - Related articles - All 25 versions
- ►nih.gov DJ Drucker - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig The gastrointestinal tract has a crucial role in the control of energy
homeostasis through its role in the digestion, absorption, and assimilation of
ingested nutrients. Furthermore, signals from the gastrointestinal tract ... Cited by 85 - Related articles - BL Direct - All 11 versions
- ►glucagon.com [PDF] - Free from Publisher MC Riddle, DJ Drucker - Diabetes Care, 2006 - Am Diabetes Assoc Current therapies for type 2 diabetes are frequently associated with inadequate
control of postprandial hyperglycemia, weight gain, and, in the case of oral
agents, loss of efficacy over time. A better understanding of physiological ... Cited by 71 - Related articles - BL Direct - All 10 versions
- ►adipo-site.net [PDF] J Klein, N Perwitz, D Kraus, M Fasshauer - Trends in Endocrinology & Metabolism, 2006 - Elsevier The physiology of adipose tissue has a key role in the pathogenesis of the
metabolic syndrome and related cardiovascular disorders. Three main functions of
adipocytes have been proposed to explain this role: the secretion of ... Cited by 33 - Related articles - All 11 versions
- ►physiology.org PL McClean, N Irwin, RS Cassidy, JJ Holst, VA … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc The gut hormone gastric inhibitory polypeptide (GIP) plays a key role in glucose
homeostasis and lipid metabolism. This study investigated the effects of
administration of a stable and specific GIP receptor antagonist, (Pro 3 ... Cited by 27 - Related articles - BL Direct - All 3 versions
N Irwin, PL McClean, FPM O'Harte, VA Gault, P … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Ablation of gastric inhibitory polypeptide (GIP)
receptor action is reported to protect against obesity and associated metabolic
abnormalities. The aim of this study was to use prediabetic ob/ob mice to ... Cited by 26 - Related articles - BL Direct - All 5 versions
- ►shouxi.net Y Yamada, K Miyawaki, K Tsukiyama, N … - Diabetes, 2006 - Am Diabetes Assoc The hormonal factor(s) implicated as transmitters of signals from the gut to
pancreatic β-cells is referred to as incretin, and gastric inhibitory
polypeptide (GIP) is identified as one of the incretins. GIP is a ... Cited by 22 - Related articles - BL Direct - All 4 versions
- ►diabetessurgeryindia.com [PDF] AL DePaula, ALV Macedo, N Rassi, CA … - Surgical Endoscopy, 2008 - Springer Abstract Background Type 2 diabetes mellitus (T2DM) is a common disease with
numerous complications. Bariatric surgery is an efficient procedure for
controlling T2DM in morbidly obese patients. In T2DM, the incretin effect ... Cited by 21 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org BJ Lamont, DJ Drucker - Diabetes, 2008 - Am Diabetes Assoc RESULTS AND CONCLUSIONS— Mice treated with vehicle alone or DA-GIP exhibited
progressive weight gain, whereas treatment with Ex-4 or DPP-4i prevented weight
gain. Although Ex-4 improved oral glucose tolerance and insulin-to-glucose ... Cited by 17 - Related articles - BL Direct - All 5 versions