AM Lincoff, K Wolski, SJ Nicholls, SE Nissen - Jama, 2007 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. ... Context Pioglitazone is widely used for glycemic ... Cited by 331 - Related articles - BL Direct - All 7 versions
- ►jhsph.edu [PDF] SE Nissen, K Wolski, EJ Topol - Jama, 2005 - Am Med Assoc Context Peroxisome proliferator–activated receptors (PPARs) are nuclear transcription factors
that modulate gene expression. Therapeutic agents targeting 2 distinct families of PPARs ( and
) have been introduced in the United States. The first dual-PPAR agonist, muraglitazar, ... Cited by 261 - Related articles - BL Direct - All 9 versions
- ►shouxi.net M Schupp, M Clemenz, R Gineste, H Witt, J Janke, S … - Diabetes, 2005 - Am Diabetes Assoc Selective peroxisome proliferator–activated receptor (PPAR) γ modulation is a new pharmacological
approach that, based on selective receptor-cofactor interactions and target gene regulation, should
result in potent insulin sensitization in the absence of PPARγ-mediated adverse effects. ... Cited by 142 - Related articles - BL Direct - All 6 versions
- ►aspetjournals.org [PDF] L Michalik, J Auwerx, JP Berger, VK Chatterjee, CK … - Pharmacological reviews, 2006 - ASPET Center for Integrative Genomics, National Research Centre “Frontiers in Genetics,” University
of Lausanne, Lausanne, Switzerland (LM, WW); Institut de Génétique et de Biologie Moléculaire
et Cellulaire, Illkirch, France (JA); Merck Research Laboratories, Rahway, New Jersey ... Cited by 134 - Related articles - BL Direct - All 7 versions
- ►endojournals.org A Grey, M Bolland, G Gamble, D Wattie, A … - Journal of Clinical …, 2007 - Endocrine Soc Context: Thiazolidinediones, which are peroxisome proliferator-activated receptor- agonists,
are widely prescribed to patients with disorders characterized by insulin resistance. Preclinical
studies suggest that peroxisome proliferator-activated receptor- signaling negatively ... Cited by 116 - Related articles - BL Direct - All 5 versions
- ►icor.com.br [PDF] JR Crouse III, JS Raichlen, WA Riley, GW Evans, MK … - Jama, 2007 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. ... Context Vasopressin mediates fluid retention in ... Cited by 107 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org JD Brown, J Plutzky - Circulation, 2007 - Am Heart Assoc Peroxisome proliferator–activated receptors (PPARs) are ligand-activated transcription factors
involved in the transcriptional regulation of key metabolic pathways such as lipid
metabolism, adipogenesis, and insulin sensitivity. More recent work implicates all 3 PPAR ... Cited by 105 - Related articles - All 8 versions
- ►nursing2008.com SE Nissen, SJ Nicholls, K Wolski, J Rodes-Cabau, CP … - Jama, 2008 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. ... Context Abdominal obesity is associated with ... Cited by 99 - Related articles - BL Direct - All 5 versions
- ►endojournals.org BL Wajchenberg - Endocrine reviews, 2007 - Endocrine Soc There is a progressive deterioration in ß-cell function and mass in type 2 diabetics. It was found
that islet function was about 50% of normal at the time of diagnosis, and a reduction in ß-cell
mass of about 60% was shown at necropsy. The reduction of ß-cell mass is attributable to ... Cited by 105 - Related articles - BL Direct - All 7 versions
A Tenenbaum, M Motro, EZ Fisman - Cardiovascular Diabetology, 2005 - biomedcentral.com There are three peroxisome proliferator-activated receptors (PPARs) subtypes which are commonly
designated PPAR alpha, PPAR gamma and PPAR beta/delta. PPAR alpha activation increases
high density lipoprotein (HDL) cholesterol synthesis, stimulates "reverse" cholesterol ... Cited by 94 - Related articles - Cached - All 13 versions
