- ►nthu.edu.tw [PDF] S Cauchi, Y El Achhab, H Choquet, C Dina, F … - Journal of Molecular Medicine, 2007 - Springer Page 1. RAPID COMMUNICATION TCF7L2 is reproducibly associated with type
2 diabetes in various ethnic groups: a global meta-analysis ... Cited by 94 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org W Winckler, MN Weedon, RR Graham, SA … - Diabetes, 2007 - Am Diabetes Assoc An important question in human genetics is the extent to which genes causing
monogenic forms of disease harbor common variants that may contribute to the
more typical form of that disease. We aimed to comprehensively evaluate the ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org MN Weedon, B Shields, G Hitman, M Walker, … - Diabetes, 2006 - Am Diabetes Assoc Ectoenzyme nucleotide pyrophosphate phosphodiesterase 1 (ENPP1) is an inhibitor
of insulin-induced activation of the insulin receptor. There is strong evidence
from several previous studies that a common coding variant of ENPP1 (K121Q) ... Cited by 48 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org W Winckler, NP Burtt, J Holmkvist, C Cervin, … - Diabetes, 2005 - Am Diabetes Assoc It is currently unclear how often genes that are mutated to cause rare,
early-onset monogenic forms of disease also harbor common variants that
contribute to the more typical polygenic form of each disease. The gene for ... Cited by 46 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org CJ Willer, LL Bonnycastle, KN Conneely, WL … - Diabetes, 2007 - Am Diabetes Assoc More than 120 published reports have described associations between single
nucleotide polymorphisms (SNPs) and type 2 diabetes. However, multiple studies
of the same variant have often been discordant. From a literature search, ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►shouxi.net LL Bonnycastle, CJ Willer, KN Conneely, AU … - Diabetes, 2006 - Am Diabetes Assoc Prior reports have suggested that variants in the genes for maturity-onset
diabetes of the young (MODY) may confer susceptibility to type 2 diabetes, but
results have been conflicting and coverage of the MODY genes has been ... Cited by 40 - Related articles - BL Direct - All 10 versions
S Ellard, K Colclough - Human mutation, 2006 - interscience.wiley.com Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes
mellitus characterized by autosomal dominant inheritance, early age of onset
(often <25 years of age), and pancreatic -cell dysfunction. MODY is both ... Cited by 32 - Related articles - BL Direct - All 4 versions
- ►nih.gov MI McCarthy, E Zeggini - Current Diabetes Reports, 2006 - Springer Introduction The growing prevalence of type 2 diabetes and obesity in societies
worldwide is widely recognized as among the greatest threats to global health in
the coming century [1]. Nevertheless, we remain far from a comprehensive ... Cited by 31 - Related articles - BL Direct - All 8 versions
JC Florez - Diabetologia, 2008 - Springer Abstract Although type 2 diabetes has been traditionally understood as a
metabolic disorder initiated by insulin resistance, it has recently become
apparent that an impairment in insulin secretion contributes to its mani- ... Cited by 31 - Related articles - BL Direct - All 3 versions
J Holmkvist, C Cervin, V Lyssenko, W Winckler … - Diabetologia, 2006 - Springer Page 1. ARTICLE Common variants in HNF-1 α and risk of type 2 diabetes J.
Holmkvist & C. Cervin & V. Lyssenko & W. Winckler & D. Anevski ... Cited by 27 - Related articles - BL Direct - All 4 versions
