- ►calvin.edu [PDF] Y Zhao, H Wang, T Mazzone - Experimental cell research, 2006 - Elsevier We identified stem cells from the umbilical cord blood, designated cord blood–stem cells
(CB–SC). CB–SC displayed important embryonic stem (ES) cell characteristics including expression
of ES-cell-specific molecular markers including transcription factors OCT-4 and Nanog, ... Cited by 60 - Related articles - All 7 versions
- ►diabetesjournals.org S Yatoh, R Dodge, T Akashi, A Omer, A Sharma, GC … - Diabetes, 2007 - Am Diabetes Assoc To test whether pancreatic duct cells are in vitro progenitors, they were purified from dispersed
islet-depleted human pancreatic tissue using CA19-9 antibody. The purified fraction was almost
entirely CK19 + with no insulin + cells, whereas the unpurified cells (crude duct) were ... Cited by 42 - Related articles - BL Direct - All 5 versions
- ►alphamedpress.org O Karnieli, Y Izhar-Prato, S Bulvik, S Efrat - Stem Cells, 2007 - AlphaMed Press We have recently shown that stable expression of pancreatic duodenal homeobox 1 (PDX1),
a transcription factor that plays key roles in pancreas development and β-cell gene
expression, in cultured human fetal liver cells activates a phenotype close to that of ... Cited by 46 - Related articles - BL Direct - All 6 versions
- ►jbc.org Z Liu, JF Habener - Journal of Biological Chemistry, 2008 - ASBMB The insulinotropic hormone GLP-1 (glucagon-like peptide-1) is a new therapeutic agent that
preserves or restores pancreatic beta cell mass. We report that GLP-1 and its agonist,
exendin-4 (Exd4), induce Wnt signaling in pancreatic beta cells, both isolated islets, and ... Cited by 34 - Related articles - All 4 versions
- ►jbc.org K Tateishi, J He, O Taranova, G Liang, AC D' … - Journal of Biological …, 2008 - ASBMB Increasing evidence suggests that islet cell transplantation for patients with type I diabetes holds
great promise for achieving insulin independence. However, the extreme shortage of matched
organ donors and the necessity for chronic immunosuppression has made it impossible ... Cited by 36 - Related articles - All 4 versions
- ►cell.com ST Gangaram-Panday, MM Faas, P de Vos - Trends in Molecular Medicine, 2007 - Elsevier Many approaches of stem-cell therapy for the treatment of diabetes have been described. One
is the application of stem cells for replacement of nonfunctional islet cells in the native endogenous
pancreas; another one is the use of stem cells as an inexhaustible source for islet-cell ... Cited by 31 - Related articles - All 6 versions
Y Li, R Zhang, H Qiao, H Zhang, Y Wang, … - Journal of cellular …, 2007 - interscience.wiley.com Islet cell replacement is considered as the optimal treatment for type I diabetes. However, the
availability of human pancreatic islets for transplantation is limited. Here, we show that human
bone marrow-derived mesenchymal stem cells (hMSCs) could be induced to differentiate ... Cited by 32 - Related articles - BL Direct - All 5 versions
- ►alphamedpress.org B Davani, L Ikonomou, BM Raaka, E Geras-Raaka, RA … - Stem Cells, 2007 - AlphaMed Press Islet transplantation offers improved glucose homeostasis in diabetic patients, but transplantation
of islets is limited by the supply of donor pancreases. Undifferentiated precursors hold promise
for cell therapy because they can expand before differentiation to produce a large supply ... Cited by 29 - Related articles - BL Direct - All 5 versions
OD Madsen - Apmis, 2005 - interscience.wiley.com Diabetes mellitus types 1 and 2 are characterized by absolute versus relative lack of insulin-producing
β cells, respectively. Reconstitution of a functional β-cell mass by cell therapy – using organ donor
islets of Langerhans – has been demonstrated to restore euglycaemia in the absence of ... Cited by 27 - Related articles - BL Direct - All 6 versions
