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Scholar Results 1 - 10 of about 14 citing Veluthakal: Essential Role for Membrane Lipid Rafts in Interleukin-1β− Induced Nitric.... (0.10 sec) 

Direct Effect of Cholesterol on Insulin Secretion

- diabetesjournals.org
M Hao, WS Head, SC Gunawardana, AH Hasty … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—Type 2 diabetes is often accompanied by abnormal blood lipid and
lipoprotein levels, but most studies on the link between hyperlipidemia and
diabetes have focused on free fatty acids (FFAs). In this study, we ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Caveolin-1 functions as a novel Cdc42 guanine nucleotide dissociation inhibitor in …

- jbc.org
AK Nevins, DC Thurmond - Journal of Biological Chemistry, 2006 - ASBMB
The cycling of the small Rho family GTPase Cdc42 is required for insulin granule
exocytosis, although the regulatory proteins involved in Cdc42 cycling in
pancreatic -cells are unknown. Here we demonstrate that the caveolar ...
Cited by 13 - Related articles - BL Direct - All 6 versions

Lack of cholesterol mobilization in islets of hormone-sensitive lipase deficient mice impairs …


S Larsson, N Wierup, F Sundler, L Eliasson, … - Biochemical and Biophysical Research …, 2008 - Elsevier
The observations that hormone-sensitive lipase (HSL) is located in close
association to insulin granules in β-cells and that cholesterol ester hydrolase
activity is completely blunted in islets of HSL null mice made us ...
Cited by 3 - Related articles - All 2 versions

Regulatory roles for histone deacetylation in IL-1β-induced nitric oxide release in pancreatic …


L Susick, R Veluthakal, MV Suresh, T Hadden … - Journal of Cellular and Molecular Medicine, 2008 - interscience.wiley.com
Histone (de)acetylases control gene transcription via modification of the
chromatin structure. Herein, we investigated potential roles for histone
deacetylation (or hypoacetylation) in interleukin-1β (IL-1β)-mediated ...
Cited by 2 - Related articles - All 2 versions

Localization of a nuclear serine/threonine protein phosphatase in insulin-secreting INS-1 cells …


R Veluthakal, BE Wadzinski, A Kowluru - Apoptosis, 2006 - Springer
Abstract Emerging evidence suggests critical roles for pro- tein phosphatase 2A
(PP2A) in islet β cell function, includ- ing survival and demise (Kowluru A:
Biochemical Pharma- col 69:1681–1691, 2005). Herein, we identified an ...
Cited by 2 - Related articles - BL Direct - All 4 versions

A novel histone deacetylase inhibitor prevents IL-1beta-induced metabolic dysfunction in …


L Susick, T Senanayake, R Veluthakal, PM … - Journal of cellular and molecular medicine, 2009 - interscience.wiley.com
The histone deacetylase [HDAC] inhibitor trichostatin A [TSA] has recently been
shown to inhibit deleterious effects of cytokines on β-cells, but it is unable
to protect β-cells from death due to its own cytotoxicity. Herein, we ...
Cited by 1 - Related articles - All 3 versions

[PDF] Increased phosphorylation of caveolin-1 in the spinal cord of irradiated rats


H Kim, C Moon, J Kim, M Ahn, JW Hyun, JW … - Journal of Veterinary Science, 2007 - vetsci.org
1Department of Veterinary Medicine, College of Applied Life Sciences, 2Applied
Radiological Science Research Institute, 3Research Institute for Subtropical
Agriculture and Biotechnology, 5Department of Biochemistry, College of ...
Cited by 1 - Related articles - View as HTML - BL Direct - All 5 versions

Small G Proteins in Islet {beta}-Cell Function


A Kowluru - Endocrine reviews, 2009 - Endocrine Soc
Glucose-stimulated insulin secretion from the islet -cell involves a sequence of
metabolic events and an in- terplay between a wide range of signaling pathways
leading to the generation of second messengers (e.g., cyclic nucleotides, ...

Mechanisms of Endotoxin-induced Suppression of Endothelial Nitric Oxide Synthase

- uncc.edu [PPT] 
W Kwok, 2009 - escholar.uncc.edu
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Related articles - View as HTML - All 3 versions

Caveolin-1 Functions as a Novel Cdc42 Guanine Nucleotide Dissociation Inhibitor in …


医学期刊, 医学会议, 医学教育, 医学书店, … - journal.shouxi.net
【摘要】 The cycling of the small Rho family GTPase Cdc42 is required for
insulin granule exocytosis, although the regulatory proteins involved in Cdc42
cycling in pancreatic -cells are unknown. Here we demonstrate that the ...
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